INPP5K and GOLT1B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		INPP5K	GOLT1B
Description		inositol polyphosphate-5-phosphatase K	golgi transport 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleus Cytoplasm Endoplasmic Reticulum Trans-Golgi Network Cytosol Plasma Membrane Membrane Ruffle Membrane Neuron Projection Perinuclear Region Of Cytoplasm	Golgi Membrane Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Endomembrane System Membrane Protein-containing Complex
	Molecular Function	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Inositol-polyphosphate 5-phosphatase Activity Vasopressin Receptor Activity Protein Binding Inositol Bisphosphate Phosphatase Activity Hydrolase Activity Phosphatase Activity Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Phosphatidylinositol Trisphosphate Phosphatase Activity Phosphatidylinositol Phosphate 5-phosphatase Activity Lipid Phosphatase Activity Inositol Trisphosphate Phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity	Protein Binding
	Biological Process	In Utero Embryonic Development Regulation Of Glycogen Biosynthetic Process Lipid Metabolic Process Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process G Protein-coupled Receptor Signaling Pathway Negative Regulation Of D-glucose Transmembrane Transport Actin Cytoskeleton Organization Response To Insulin Cellular Response To Insulin Stimulus Cellular Response To Hormone Stimulus Negative Regulation Of Dephosphorylation Positive Regulation Of Urine Volume Glucose Homeostasis Host-mediated Suppression Of Viral Transcription Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Glycerolipid Metabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol Dephosphorylation Regulation Of Transport Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Calcium Ion Transport Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Negative Regulation Of Protein Targeting To Membrane Ruffle Assembly Cellular Response To Oxygen-containing Compound Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Renal Water Transport	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Canonical NF-kappaB Signal Transduction
Pathways		Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Mean platelet volume ( 27863252)
Interacting Genes		23 interacting genes: ANXA7 ARL6IP1 ATP5PF BDNF CDKN1A CPTP FADS6 FATE1 FBXO7 GOLT1B HMOX2 HSPB1 KRT31 NCOR2 PBX3 PFDN1 SFT2D2 SMN1 TANK TK1 TNFRSF10D TNKS TTR	12 interacting genes: CREB3L1 FNDC3B GPR152 INPP5K LMNA MUC1 SAR1A SDCBP SH3GL3 SHISAL2A SLC10A6 SPG21
Entrez ID		51763	51026
HPRD ID		08489	13035
Ensembl ID		ENSG00000132376	ENSG00000111711
Uniprot IDs		B7Z4V9 Q9BT40	Q9Y3E0
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Apoptotic Signaling Pathway Membrane Interleukin-5 Receptor Complex Negative Regulation Of Receptor-mediated Endocytosis Response To Epidermal Growth Factor Positive Regulation Of Renal Water Transport Phosphatidylinositol Trisphosphate Phosphatase Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport
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