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INPP5K
Gene Name
inositol polyphosphate-5-phosphatase K
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Ruffle
Nucleus
Cytoplasm
Endoplasmic Reticulum
Trans-Golgi Network
Cytosol
Plasma Membrane
Membrane
Ruffle Membrane
Neuron Projection
Perinuclear Region Of Cytoplasm
Molecular Function
Inositol-polyphosphate 5-phosphatase Activity
Vasopressin Receptor Activity
Protein Binding
Inositol Bisphosphate Phosphatase Activity
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Phosphatidylinositol Trisphosphate Phosphatase Activity
Phosphatidylinositol Phosphate 5-phosphatase Activity
Lipid Phosphatase Activity
Inositol Trisphosphate Phosphatase Activity
Inositol-1,4,5-trisphosphate 5-phosphatase Activity
Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
Biological Process
In Utero Embryonic Development
Negative Regulation Of Protein Phosphorylation
Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Protein Kinase Activity
Phospholipid Metabolic Process
Phosphatidylinositol Biosynthetic Process
G-protein Coupled Receptor Signaling Pathway
Negative Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Glucose Transport
Dephosphorylation
Actin Cytoskeleton Organization
Cellular Response To Insulin Stimulus
Cellular Response To Hormone Stimulus
Negative Regulation Of Peptidyl-serine Phosphorylation
Negative Regulation Of Dephosphorylation
Positive Regulation Of Urine Volume
Glucose Homeostasis
Negative Regulation Of MAP Kinase Activity
Negative Regulation By Host Of Viral Transcription
Small Molecule Metabolic Process
Negative Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Insulin Receptor Signaling Pathway
Inositol Phosphate Dephosphorylation
Phosphatidylinositol Dephosphorylation
Negative Regulation Of Stress Fiber Assembly
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Calcium Ion Transport
Cellular Response To CAMP
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Protein Targeting To Plasma Membrane
Negative Regulation Of Protein Targeting To Membrane
Ruffle Assembly
Negative Regulation Of Glycogen (starch) Synthase Activity
Positive Regulation Of Renal Water Transport
Pathways
Synthesis of PIPs at the plasma membrane
Metabolism of lipids and lipoproteins
Phospholipid metabolism
PI Metabolism
Drugs
Diseases
GWAS
Protein-protein Interactions
15 interactors:
ANXA7
ARL6IP1
BDNF
CDKN1A
CPTP
FATE1
HMOX2
KRT31
MAD2L1BP
NCOR2
PFDN1
SMN1
TANK
TK1
TTR
Entrez ID
51763
HPRD ID
08489
Ensembl ID
ENSG00000132376
Uniprot IDs
B7Z4V9
F5GXZ0
Q9BT40
PDB IDs
Enriched GO Terms of Interacting Partners
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Response To Organic Cyclic Compound
Response To Hyperoxia
Epithelium Development
Response To Abiotic Stimulus
Tube Development
Response To Anesthetic
Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter
Ceramide 1-phosphate Transport
Fetal Process Involved In Parturition
Response To Fluoxetine
Response To L-glutamate
Response To Metal Ion
Response To Light Stimulus
Response To Lipid
Skeletal Muscle Cell Proliferation
Response To Hormone
Taste Bud Development
Dendrite Extension
Heme Oxidation
Cellular Response To Norepinephrine Stimulus
Regulation Of Retinal Cell Programmed Cell Death
Response To Radiation
Tissue Development
Response To Extracellular Stimulus
Ceramide Transport
Response To Inorganic Substance
Response To Steroid Hormone
Anatomical Structure Development
Thyroid Hormone Transport
Intestinal Epithelial Cell Maturation
Axon Target Recognition
Digestive Tract Development
Response To Norepinephrine
Response To Ether
Response To Cortisol
Thymidine Metabolic Process
Epithelial Cell Differentiation
Digestive System Development
Response To Glucocorticoid
Mitotic Cell Cycle Checkpoint
Cellular Response To Growth Factor Stimulus
Response To Corticosteroid
Deoxyribonucleoside Monophosphate Biosynthetic Process
Negative Regulation Of Synaptic Transmission, GABAergic
Cellular Response To UV-B
Positive Regulation Of Long-term Neuronal Synaptic Plasticity
Heme Catabolic Process
Response To Growth Factor
Response To Toxic Substance
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