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INPP5K and HMOX2
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
INPP5K
HMOX2
Gene Name
inositol polyphosphate-5-phosphatase K
heme oxygenase (decycling) 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Ruffle
Nucleus
Cytoplasm
Endoplasmic Reticulum
Trans-Golgi Network
Cytosol
Plasma Membrane
Membrane
Ruffle Membrane
Neuron Projection
Perinuclear Region Of Cytoplasm
Endoplasmic Reticulum Membrane
Plasma Membrane
Membrane
Molecular Function
Inositol-polyphosphate 5-phosphatase Activity
Vasopressin Receptor Activity
Protein Binding
Inositol Bisphosphate Phosphatase Activity
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Phosphatidylinositol Trisphosphate Phosphatase Activity
Phosphatidylinositol Phosphate 5-phosphatase Activity
Lipid Phosphatase Activity
Inositol Trisphosphate Phosphatase Activity
Inositol-1,4,5-trisphosphate 5-phosphatase Activity
Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
Heme Oxygenase (decyclizing) Activity
Protein Binding
Metal Ion Binding
Biological Process
In Utero Embryonic Development
Negative Regulation Of Protein Phosphorylation
Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Protein Kinase Activity
Phospholipid Metabolic Process
Phosphatidylinositol Biosynthetic Process
G-protein Coupled Receptor Signaling Pathway
Negative Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Glucose Transport
Dephosphorylation
Actin Cytoskeleton Organization
Cellular Response To Insulin Stimulus
Cellular Response To Hormone Stimulus
Negative Regulation Of Peptidyl-serine Phosphorylation
Negative Regulation Of Dephosphorylation
Positive Regulation Of Urine Volume
Glucose Homeostasis
Negative Regulation Of MAP Kinase Activity
Negative Regulation By Host Of Viral Transcription
Small Molecule Metabolic Process
Negative Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Insulin Receptor Signaling Pathway
Inositol Phosphate Dephosphorylation
Phosphatidylinositol Dephosphorylation
Negative Regulation Of Stress Fiber Assembly
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Calcium Ion Transport
Cellular Response To CAMP
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Protein Targeting To Plasma Membrane
Negative Regulation Of Protein Targeting To Membrane
Ruffle Assembly
Negative Regulation Of Glycogen (starch) Synthase Activity
Positive Regulation Of Renal Water Transport
Response To Hypoxia
Porphyrin-containing Compound Metabolic Process
Heme Oxidation
Cellular Iron Ion Homeostasis
Heme Catabolic Process
Small Molecule Metabolic Process
Transmembrane Transport
Pathways
Synthesis of PIPs at the plasma membrane
Metabolism of lipids and lipoproteins
Phospholipid metabolism
PI Metabolism
Iron uptake and transport
Metabolism of porphyrins
Heme degradation
Drugs
NADH
Diseases
GWAS
Protein-Protein Interactions
15 interactors:
ANXA7
ARL6IP1
BDNF
CDKN1A
CPTP
FATE1
HMOX2
KRT31
MAD2L1BP
NCOR2
PFDN1
SMN1
TANK
TK1
TTR
32 interactors:
A2M
APP
ATP5B
BLOC1S2
CEBPZ
COPS6
CSNK2A1
EEF1G
EIF3C
GIT1
GPRASP1
HAP1
IMMT
INPP5K
ITFG1
JADE1
KCNMA1
KIAA1377
LRIF1
MED31
NDUFS2
NKRF
NR3C1
PLXNB2
RBBP4
SETDB1
SHC1
SKA2
SNX5
SNX7
ZFP28
ZNF746
Entrez ID
51763
3163
HPRD ID
08489
00783
Ensembl ID
ENSG00000132376
ENSG00000103415
Uniprot IDs
B7Z4V9
F5GXZ0
Q9BT40
I3L430
P30519
PDB IDs
2Q32
2QPP
2RGZ
Enriched GO Terms of Interacting Partners
?
Response To Organic Cyclic Compound
Response To Hyperoxia
Epithelium Development
Response To Abiotic Stimulus
Tube Development
Response To Anesthetic
Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter
Ceramide 1-phosphate Transport
Fetal Process Involved In Parturition
Response To Fluoxetine
Response To L-glutamate
Response To Metal Ion
Response To Light Stimulus
Response To Lipid
Skeletal Muscle Cell Proliferation
Response To Hormone
Taste Bud Development
Dendrite Extension
Heme Oxidation
Cellular Response To Norepinephrine Stimulus
Regulation Of Retinal Cell Programmed Cell Death
Response To Radiation
Tissue Development
Response To Extracellular Stimulus
Ceramide Transport
Response To Inorganic Substance
Response To Steroid Hormone
Anatomical Structure Development
Thyroid Hormone Transport
Intestinal Epithelial Cell Maturation
Axon Target Recognition
Digestive Tract Development
Response To Norepinephrine
Response To Ether
Response To Cortisol
Thymidine Metabolic Process
Epithelial Cell Differentiation
Digestive System Development
Response To Glucocorticoid
Mitotic Cell Cycle Checkpoint
Cellular Response To Growth Factor Stimulus
Response To Corticosteroid
Deoxyribonucleoside Monophosphate Biosynthetic Process
Negative Regulation Of Synaptic Transmission, GABAergic
Cellular Response To UV-B
Positive Regulation Of Long-term Neuronal Synaptic Plasticity
Heme Catabolic Process
Response To Growth Factor
Response To Toxic Substance
Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Axon Cargo Transport
Cellular Macromolecule Biosynthetic Process
Organelle Organization
Macromolecule Biosynthetic Process
RNA Metabolic Process
Biosynthetic Process
Regulation Of Transcription, DNA-templated
Cellular Process
Regulation Of Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of ERBB Signaling Pathway
Regulation Of Mitotic Cell Cycle Phase Transition
Nucleobase-containing Compound Metabolic Process
Regulation Of Cell Cycle Phase Transition
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Cell Cycle Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Receptor Activity
Cell Projection Organization
Cellular Nitrogen Compound Metabolic Process
Anterograde Axon Cargo Transport
Microtubule-based Transport
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Regulation Of Body Fluid Levels
Cytoskeleton-dependent Intracellular Transport
Regulation Of Cell Cycle
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Neurotrophin Production
Positive Regulation Of Nonmotile Primary Cilium Assembly
Glucocorticoid Mediated Signaling Pathway
Positive Regulation Of Renal Water Transport
Regulation Of Cellular Process
Nitrogen Compound Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Signal Transduction
Cellular Response To CAMP
Cellular Homeostasis
Regulation Of Mitotic Cell Cycle
Platelet Activation
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