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INPP5K and TTR
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
INPP5K
TTR
Gene Name
inositol polyphosphate-5-phosphatase K
transthyretin
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Ruffle
Nucleus
Cytoplasm
Endoplasmic Reticulum
Trans-Golgi Network
Cytosol
Plasma Membrane
Membrane
Ruffle Membrane
Neuron Projection
Perinuclear Region Of Cytoplasm
Extracellular Region
Extracellular Space
Cytoplasm
Protein Complex
Extracellular Vesicular Exosome
Molecular Function
Inositol-polyphosphate 5-phosphatase Activity
Vasopressin Receptor Activity
Protein Binding
Inositol Bisphosphate Phosphatase Activity
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Phosphatidylinositol Trisphosphate Phosphatase Activity
Phosphatidylinositol Phosphate 5-phosphatase Activity
Lipid Phosphatase Activity
Inositol Trisphosphate Phosphatase Activity
Inositol-1,4,5-trisphosphate 5-phosphatase Activity
Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
Hormone Activity
Protein Binding
Identical Protein Binding
Protein Heterodimerization Activity
Thyroid Hormone Binding
Biological Process
In Utero Embryonic Development
Negative Regulation Of Protein Phosphorylation
Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Protein Kinase Activity
Phospholipid Metabolic Process
Phosphatidylinositol Biosynthetic Process
G-protein Coupled Receptor Signaling Pathway
Negative Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Glucose Transport
Dephosphorylation
Actin Cytoskeleton Organization
Cellular Response To Insulin Stimulus
Cellular Response To Hormone Stimulus
Negative Regulation Of Peptidyl-serine Phosphorylation
Negative Regulation Of Dephosphorylation
Positive Regulation Of Urine Volume
Glucose Homeostasis
Negative Regulation Of MAP Kinase Activity
Negative Regulation By Host Of Viral Transcription
Small Molecule Metabolic Process
Negative Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Insulin Receptor Signaling Pathway
Inositol Phosphate Dephosphorylation
Phosphatidylinositol Dephosphorylation
Negative Regulation Of Stress Fiber Assembly
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Calcium Ion Transport
Cellular Response To CAMP
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Protein Targeting To Plasma Membrane
Negative Regulation Of Protein Targeting To Membrane
Ruffle Assembly
Negative Regulation Of Glycogen (starch) Synthase Activity
Positive Regulation Of Renal Water Transport
Retinoid Metabolic Process
Transport
Phototransduction, Visible Light
Extracellular Matrix Organization
Retinol Metabolic Process
Thyroid Hormone Transport
Pathways
Synthesis of PIPs at the plasma membrane
Metabolism of lipids and lipoproteins
Phospholipid metabolism
PI Metabolism
Amyloids
Visual phototransduction
The canonical retinoid cycle in rods (twilight vision)
Retinoid cycle disease events
Non-integrin membrane-ECM interactions
Diseases associated with visual transduction
Retinoid metabolism and transport
Drugs
Diseases
GWAS
Retinol levels (
21878437
)
Protein-Protein Interactions
15 interactors:
ANXA7
ARL6IP1
BDNF
CDKN1A
CPTP
FATE1
HMOX2
KRT31
MAD2L1BP
NCOR2
PFDN1
SMN1
TANK
TK1
TTR
46 interactors:
A2M
ACTB
AGER
APOA1
ASNA1
ATF4
BAG6
C14orf1
CDR2
CHD3
CLU
CPNE6
CTNND2
DDR1
EEF1A1
FEZ1
GET4
HNRNPH3
HSPG2
IKBKAP
INPP5K
KIAA1377
LRP2
MARK3
MT3
NECAB2
NGFR
OTUB1
PHYHIP
PIK3R1
PRKCI
QARS
RAI1
RBP4
RNF115
SDF4
SETDB1
SP110
ST13
ST3GAL3
SUMO3
TAF1C
TAF5L
TUBA1A
VIM
ZBED1
Entrez ID
51763
7276
HPRD ID
08489
01447
Ensembl ID
ENSG00000132376
ENSG00000118271
Uniprot IDs
B7Z4V9
F5GXZ0
Q9BT40
E9KL36
P02766
PDB IDs
1BM7
1BMZ
1BZ8
1BZD
1BZE
1DVQ
1DVS
1DVT
1DVU
1DVX
1DVY
1DVZ
1E3F
1E4H
1E5A
1ETA
1ETB
1F41
1F64
1F86
1FH2
1FHN
1G1O
1GKO
1ICT
1III
1IIK
1IJN
1QAB
1QWH
1RLB
1SOK
1SOQ
1THA
1THC
1TLM
1TSH
1TT6
1TTA
1TTB
1TTC
1TTR
1TYR
1TZ8
1U21
1X7S
1X7T
1Y1D
1Z7J
1ZCR
1ZD6
2B14
2B15
2B16
2B77
2B9A
2F7I
2F8I
2FBR
2FLM
2G3X
2G3Z
2G4E
2G4G
2G5U
2G9K
2GAB
2H4E
2M5N
2NOY
2PAB
2QEL
2QGB
2QGC
2QGD
2QGE
2ROX
2ROY
2TRH
2TRY
2WQA
3A4D
3A4E
3A4F
3B56
3BSZ
3BT0
3CBR
3CFM
3CFN
3CFQ
3CFT
3CN0
3CN1
3CN2
3CN3
3CN4
3CXF
3D2T
3D7P
3DGD
3DID
3DJR
3DJS
3DJT
3DJZ
3DK0
3DK2
3DO4
3ESN
3ESO
3ESP
3FC8
3FCB
3GLZ
3GPS
3GRB
3GRG
3GS0
3GS4
3GS7
3HJ0
3I9A
3I9I
3I9P
3IMR
3IMS
3IMT
3IMU
3IMV
3IMW
3IPB
3IPE
3KGS
3KGT
3KGU
3M1O
3NEE
3NEO
3NES
3NEX
3NG5
3OZK
3OZL
3P3R
3P3S
3P3T
3P3U
3SSG
3TCT
3TFB
3U2I
3U2J
3W3B
4ABQ
4ABU
4ABV
4ABW
4AC2
4AC4
4ACT
4ANK
4DER
4DES
4DET
4DEU
4DEW
4FI6
4FI7
4FI8
4HIQ
4HIS
4I85
4I87
4I89
4IIZ
4IK6
4IK7
4IKI
4IKJ
4IKK
4IKL
4KY2
4L1S
4L1T
4MAS
5TTR
Enriched GO Terms of Interacting Partners
?
Response To Organic Cyclic Compound
Response To Hyperoxia
Epithelium Development
Response To Abiotic Stimulus
Tube Development
Response To Anesthetic
Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter
Ceramide 1-phosphate Transport
Fetal Process Involved In Parturition
Response To Fluoxetine
Response To L-glutamate
Response To Metal Ion
Response To Light Stimulus
Response To Lipid
Skeletal Muscle Cell Proliferation
Response To Hormone
Taste Bud Development
Dendrite Extension
Heme Oxidation
Cellular Response To Norepinephrine Stimulus
Regulation Of Retinal Cell Programmed Cell Death
Response To Radiation
Tissue Development
Response To Extracellular Stimulus
Ceramide Transport
Response To Inorganic Substance
Response To Steroid Hormone
Anatomical Structure Development
Thyroid Hormone Transport
Intestinal Epithelial Cell Maturation
Axon Target Recognition
Digestive Tract Development
Response To Norepinephrine
Response To Ether
Response To Cortisol
Thymidine Metabolic Process
Epithelial Cell Differentiation
Digestive System Development
Response To Glucocorticoid
Mitotic Cell Cycle Checkpoint
Cellular Response To Growth Factor Stimulus
Response To Corticosteroid
Deoxyribonucleoside Monophosphate Biosynthetic Process
Negative Regulation Of Synaptic Transmission, GABAergic
Cellular Response To UV-B
Positive Regulation Of Long-term Neuronal Synaptic Plasticity
Heme Catabolic Process
Response To Growth Factor
Response To Toxic Substance
Protein Insertion Into ER Membrane
Anatomical Structure Development
Developmental Process
Protein Stabilization
Protein Metabolic Process
Cellular Protein Metabolic Process
Multicellular Organismal Development
Regulation Of Protein Stability
Nervous System Development
Central Nervous System Development
Regulation Of Gene Expression
Protein Insertion Into Membrane
System Development
Cellular Localization
Phototransduction, Visible Light
Retinoid Metabolic Process
Detection Of Abiotic Stimulus
Diterpenoid Metabolic Process
Detection Of Visible Light
Cellular Response To Stimulus
Platelet Activation
Phototransduction
Response To Light Stimulus
Chromatin Organization
Regulation Of Glucose Transport
Alcohol Metabolic Process
Detection Of Light Stimulus
Organelle Organization
Establishment Of Protein Localization To Membrane
Metabolic Process
Lipid Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress
Tail-anchored Membrane Protein Insertion Into ER Membrane
Regulation Of Metabolic Process
Regulation Of Body Fluid Levels
Regulation Of Protein Metabolic Process
Cellular Metabolic Process
Isoprenoid Metabolic Process
Response To Organic Substance
Endoplasmic Reticulum Organization
Chromatin Modification
Regulation Of Cellular Protein Metabolic Process
Membrane Organization
Response To Radiation
Negative Regulation Of Protein Metabolic Process
Posttranscriptional Regulation Of Gene Expression
Response To Wounding
Signaling
Regulation Of Glucose Import
Cellular Protein Modification Process
Tagcloud
?
arteriovenous
carotid
clamped
conscious
constant
cooled
cooling
degree
depend
destined
driving
extrahypothalamic
gain
goats
hypothalamic
hypothalamus
loops
manipulate
passage
rete
sbc
shunt
tbr
temperatures
termed
texh
thermodes
thyp
trunk
Tagcloud (Difference)
?
arteriovenous
carotid
clamped
conscious
constant
cooled
cooling
degree
depend
destined
driving
extrahypothalamic
gain
goats
hypothalamic
hypothalamus
loops
manipulate
passage
rete
sbc
shunt
tbr
temperatures
termed
texh
thermodes
thyp
trunk
Tagcloud (Intersection)
?