INPP5K and FATE1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		INPP5K	FATE1
Gene Name		inositol polyphosphate-5-phosphatase K	fetal and adult testis expressed 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Cytoplasm Endoplasmic Reticulum Trans-Golgi Network Cytosol Plasma Membrane Membrane Ruffle Membrane Neuron Projection Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Integral Component Of Membrane
	Molecular Function	Inositol-polyphosphate 5-phosphatase Activity Vasopressin Receptor Activity Protein Binding Inositol Bisphosphate Phosphatase Activity Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Phosphatidylinositol Trisphosphate Phosphatase Activity Phosphatidylinositol Phosphate 5-phosphatase Activity Lipid Phosphatase Activity Inositol Trisphosphate Phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity	Protein Binding
	Biological Process	In Utero Embryonic Development Negative Regulation Of Protein Phosphorylation Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Protein Kinase Activity Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Glucose Transport Dephosphorylation Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Cellular Response To Hormone Stimulus Negative Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Dephosphorylation Positive Regulation Of Urine Volume Glucose Homeostasis Negative Regulation Of MAP Kinase Activity Negative Regulation By Host Of Viral Transcription Small Molecule Metabolic Process Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Insulin Receptor Signaling Pathway Inositol Phosphate Dephosphorylation Phosphatidylinositol Dephosphorylation Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Calcium Ion Transport Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Targeting To Plasma Membrane Negative Regulation Of Protein Targeting To Membrane Ruffle Assembly Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Renal Water Transport
Pathways		Synthesis of PIPs at the plasma membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: ANXA7 ARL6IP1 BDNF CDKN1A CPTP FATE1 HMOX2 KRT31 MAD2L1BP NCOR2 PFDN1 SMN1 TANK TK1 TTR	49 interactors: AGTRAP AQP9 BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 CCDC155 CCDC70 CD302 CD79A CSF2RA DCTN5 EMD GPR25 INPP5K KCNS2 LNPEP MARCH2 MARCH5 MR1 NDUFB11 NRG4 NRSN1 PIN4 PRRG2 RNF183 RPRM SEC22A SEC22C SEC23B SLC38A1 SLC7A1 SNAP47 SYNDIG1 SYNE4 SYNGR1 SYNPR TBP TIMMDC1 TM4SF4 TMEM74 TRAF2 TRAF3IP3 USHBP1 USP20 YIPF4
Entrez ID		51763	89885
HPRD ID		08489	02346
Ensembl ID		ENSG00000132376	ENSG00000147378
Uniprot IDs		B7Z4V9 F5GXZ0 Q9BT40	Q969F0
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Organic Cyclic Compound Response To Hyperoxia Epithelium Development Response To Abiotic Stimulus Tube Development Response To Anesthetic Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Ceramide 1-phosphate Transport Fetal Process Involved In Parturition Response To Fluoxetine Response To L-glutamate Response To Metal Ion Response To Light Stimulus Response To Lipid Skeletal Muscle Cell Proliferation Response To Hormone Taste Bud Development Dendrite Extension Heme Oxidation Cellular Response To Norepinephrine Stimulus Regulation Of Retinal Cell Programmed Cell Death Response To Radiation Tissue Development Response To Extracellular Stimulus Ceramide Transport Response To Inorganic Substance Response To Steroid Hormone Anatomical Structure Development Thyroid Hormone Transport Intestinal Epithelial Cell Maturation Axon Target Recognition Digestive Tract Development Response To Norepinephrine Response To Ether Response To Cortisol Thymidine Metabolic Process Epithelial Cell Differentiation Digestive System Development Response To Glucocorticoid Mitotic Cell Cycle Checkpoint Cellular Response To Growth Factor Stimulus Response To Corticosteroid Deoxyribonucleoside Monophosphate Biosynthetic Process Negative Regulation Of Synaptic Transmission, GABAergic Cellular Response To UV-B Positive Regulation Of Long-term Neuronal Synaptic Plasticity Heme Catabolic Process Response To Growth Factor Response To Toxic Substance	Mitochondrial Protein Catabolic Process Membrane Organization Vesicle Fusion With Golgi Apparatus Vesicle Fusion Positive Regulation Of Mitochondrial Fission Mitochondrial Outer Membrane Permeabilization Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Fission Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Apoptotic Mitochondrial Changes Organelle Fusion Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Mitochondrion Organization ER To Golgi Vesicle-mediated Transport Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Transport Positive Regulation Of Release Of Cytochrome C From Mitochondria Membrane Fusion Establishment Of Localization In Cell Regulation Of Mitochondrial Membrane Permeability Chromosome Localization To Nuclear Envelope Involved In Synapsis Positive Regulation Of Renal Water Transport Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Cellular Localization Regulation Of Membrane Permeability Protein Autoubiquitination
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