PIAS4 and MDC1

  • Number of citations of the paper that reports this interaction (PMID 22661230)
  • 32
  • Data Source:
  • BioGRID (enzymatic study)

PIAS4

MDC1

Gene Name protein inhibitor of activated STAT, 4 mediator of DNA-damage checkpoint 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 75 interactors: ACTN1 ALDOA AR BARD1 BRCA1 BTAF1 CALCOCO2 CEBPD CHD3 CLK1 COIL ESRRA FTH1 GADD45G HDAC1 HDAC2 HNF4A HNRNPUL1 HTT IL15RA IMMT IMPDH2 IRF3 IRF7 KPNB1 KRT18 LAMP2 LEF1 LRIF1 MAGEH1 MAP1LC3A MDC1 MPRIP NEFL NR4A2 OAZ1 OPTN PARP1 PDE4A PDE4D PDE4DIP PHF11 PHGDH PIAS1 PIAS2 PLAG1 PRPF40A PTN RIF1 SATB1 SERBP1 SERPINA5 SETDB1 SH3GL3 SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 SNIP1 SUMO1 SUMO2 SUMO3 TADA3 TCERG1 TICAM1 TP53 TRIM27 TRIM32 UBE2I UBE2K VIM ZHX1 ZNF512B 37 interactors: ANAPC1 ATM BARD1 BRCA1 CASP3 CENPC CHEK2 COPS5 CREBBP CSNK2A1 DTX2 EP300 GATA4 H2AFX HDAC10 HDAC8 HINFP LOC729324 NBN NCL PIAS1 PIAS4 PRIM1 RAD50 RAD51 RNF8 SMC1A SUMO1 SUMO2 TP53 TP53BP1 UIMC1 USP28 VAMP5 WHSC1 WRN ZNF251
Entrez ID 51588 9656
HPRD ID 06910 16252
Ensembl ID ENSG00000137337
Uniprot IDs Q8N2W9 A1Z5I9 Q14676
PDB IDs 2ADO 2AZM 2ETX 3K05 3UEO 3UMZ 3UN0 3UNM 3UNN 3UOT
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acceptor  acetyltransferase  alignment  consensus  consequently  deacetylase  dgcr8  e195a  e3  ing  ing1  ing1b  ing2  ing3  ings  isg15  k193  ligase  marks  mislocalized  pdsm  phosphomimic  preferred  reveals  s199d  stoichiometric  sumo  sumoylation  suppressors 
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  rad51  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
Tagcloud (Difference) ?
acceptor  acetyltransferase  alignment  consensus  consequently  deacetylase  dgcr8  e195a  e3  ing  ing1  ing1b  ing2  ing3  ings  isg15  k193  ligase  marks  mislocalized  pdsm  phosphomimic  preferred  reveals  s199d  stoichiometric  sumo  sumoylation  suppressors 
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  rad51  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
Tagcloud (Intersection) ?