PIAS4 and PHF11

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PIAS4	PHF11
Gene Name		protein inhibitor of activated STAT, 4	PHD finger protein 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix PML Body	Nucleus
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Ligase Activity SUMO Transferase Activity Ubiquitin Protein Ligase Binding SUMO Ligase Activity	Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Wnt Signaling Pathway Protein Sumoylation Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Protein Sumoylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Keratinocyte Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Cardiac hypertrophy ( 21348951)
Protein-Protein Interactions		75 interactors: ACTN1 ALDOA AR BARD1 BRCA1 BTAF1 CALCOCO2 CEBPD CHD3 CLK1 COIL ESRRA FTH1 GADD45G HDAC1 HDAC2 HNF4A HNRNPUL1 HTT IL15RA IMMT IMPDH2 IRF3 IRF7 KPNB1 KRT18 LAMP2 LEF1 LRIF1 MAGEH1 MAP1LC3A MDC1 MPRIP NEFL NR4A2 OAZ1 OPTN PARP1 PDE4A PDE4D PDE4DIP PHF11 PHGDH PIAS1 PIAS2 PLAG1 PRPF40A PTN RIF1 SATB1 SERBP1 SERPINA5 SETDB1 SH3GL3 SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 SNIP1 SUMO1 SUMO2 SUMO3 TADA3 TCERG1 TICAM1 TP53 TRIM27 TRIM32 UBE2I UBE2K VIM ZHX1 ZNF512B	5 interactors: AGPAT2 CSNK2B LSM8 MCPH1 PIAS4
Entrez ID		51588	51131
HPRD ID		06910	08480
Ensembl ID			ENSG00000136147
Uniprot IDs		Q8N2W9	Q9UIL8
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Cellular Response To Organic Substance Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription, DNA-templated Response To Organic Substance Regulation Of Cellular Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Gene Expression Response To Stimulus Positive Regulation Of Gene Expression Protein Sumoylation DNA-templated Transcription, Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Cellular Response To Organic Cyclic Compound Positive Regulation Of Transcription, DNA-templated Transforming Growth Factor Beta Receptor Signaling Pathway Response To Stress Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Cellular Metabolic Process Response To Transforming Growth Factor Beta Regulation Of Cell Death	Positive Regulation Of Keratinocyte Apoptotic Process Regulation Of Chromosome Condensation Wnt Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Activin Receptor Signaling Pathway Adiponectin-activated Signaling Pathway Endothelial Tube Morphogenesis CDP-diacylglycerol Biosynthetic Process CDP-diacylglycerol Metabolic Process Protein Localization To Centrosome Positive Regulation Of Protein Sumoylation
Tagcloud ?		acceptor acetyltransferase alignment consensus consequently deacetylase dgcr8 e195a e3 ing ing1 ing1b ing2 ing3 ings isg15 k193 ligase marks mislocalized pdsm phosphomimic preferred reveals s199d stoichiometric sumo sumoylation suppressors	aeroallergen allergen asthma asthmatic asthmatics atopy bronchodilator call caucasian eczema genotyped hardy helper homeodomain ige multiplex nineteen positional prick schools sensitization snapshot snps spirometric spirometry tagging weakly weinberg wheal
Tagcloud (Difference) ?		acceptor acetyltransferase alignment consensus consequently deacetylase dgcr8 e195a e3 ing ing1 ing1b ing2 ing3 ings isg15 k193 ligase marks mislocalized pdsm phosphomimic preferred reveals s199d stoichiometric sumo sumoylation suppressors	aeroallergen allergen asthma asthmatic asthmatics atopy bronchodilator call caucasian eczema genotyped hardy helper homeodomain ige multiplex nineteen positional prick schools sensitization snapshot snps spirometric spirometry tagging weakly weinberg wheal
Tagcloud (Intersection) ?