PIAS4 and SATB1

Number of citations of the paper that reports this interaction (PMID 18408014)
14

Data Source:
BioGRID (two hybrid, two hybrid)

		PIAS4	SATB1
Gene Name		protein inhibitor of activated STAT, 4	SATB homeobox 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix PML Body	Nucleus Nucleoplasm Nuclear Heterochromatin Nuclear Matrix PML Body
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Ligase Activity SUMO Transferase Activity Ubiquitin Protein Ligase Binding SUMO Ligase Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Chromatin Binding Double-stranded DNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Wnt Signaling Pathway Protein Sumoylation Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Protein Sumoylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Keratinocyte Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Epidermis Development Viral Process Histone Methylation CD4-positive, Alpha-beta T Cell Differentiation CD8-positive, Alpha-beta T Cell Differentiation Activated T Cell Proliferation Reflex
Pathways			Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS			Platelet counts ( 22139419)
Protein-Protein Interactions		75 interactors: ACTN1 ALDOA AR BARD1 BRCA1 BTAF1 CALCOCO2 CEBPD CHD3 CLK1 COIL ESRRA FTH1 GADD45G HDAC1 HDAC2 HNF4A HNRNPUL1 HTT IL15RA IMMT IMPDH2 IRF3 IRF7 KPNB1 KRT18 LAMP2 LEF1 LRIF1 MAGEH1 MAP1LC3A MDC1 MPRIP NEFL NR4A2 OAZ1 OPTN PARP1 PDE4A PDE4D PDE4DIP PHF11 PHGDH PIAS1 PIAS2 PLAG1 PRPF40A PTN RIF1 SATB1 SERBP1 SERPINA5 SETDB1 SH3GL3 SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 SNIP1 SUMO1 SUMO2 SUMO3 TADA3 TCERG1 TICAM1 TP53 TRIM27 TRIM32 UBE2I UBE2K VIM ZHX1 ZNF512B	23 interactors: BAZ1A CASP6 CBX4 CHD3 CUX1 DYT10 EP300 GATA3 HDAC1 KAT2B MTA2 PIAS1 PIAS3 PIAS4 POLR2J SIRT1 SMARCA5 SUMO1 SUMO1P1 SUMO3 TOPORS UBE2I UBR5
Entrez ID		51588	6304
HPRD ID		06910	03647
Ensembl ID			ENSG00000182568
Uniprot IDs		Q8N2W9	Q01826
PDB IDs			1YSE 2L1P 2O49 2O4A 3NZL 3TUO
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Cellular Response To Organic Substance Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription, DNA-templated Response To Organic Substance Regulation Of Cellular Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Gene Expression Response To Stimulus Positive Regulation Of Gene Expression Protein Sumoylation DNA-templated Transcription, Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Cellular Response To Organic Cyclic Compound Positive Regulation Of Transcription, DNA-templated Transforming Growth Factor Beta Receptor Signaling Pathway Response To Stress Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Cellular Metabolic Process Response To Transforming Growth Factor Beta Regulation Of Cell Death	Protein Sumoylation Peptidyl-lysine Modification Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Modification By Small Protein Conjugation RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Peptidyl-amino Acid Modification Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Chromatin Modification Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Chromatin Organization Positive Regulation Of Metabolic Process Gene Expression Chromatin Remodeling Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Protein Modification Process Chromosome Organization Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Sumoylation Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process Biosynthetic Process Regulation Of Protein Sumoylation Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway Cellular Protein Metabolic Process
Tagcloud ?		acceptor acetyltransferase alignment consensus consequently deacetylase dgcr8 e195a e3 ing ing1 ing1b ing2 ing3 ings isg15 k193 ligase marks mislocalized pdsm phosphomimic preferred reveals s199d stoichiometric sumo sumoylation suppressors	biomarker clinicopathologic confidence depth endometrial federation gynecology hazards histological international interval invasion lymphatic metastasis myometrial node obstetrics organizer overexpressed parameter predicting prognostic rich serve serves special treating untreated worse
Tagcloud (Difference) ?		acceptor acetyltransferase alignment consensus consequently deacetylase dgcr8 e195a e3 ing ing1 ing1b ing2 ing3 ings isg15 k193 ligase marks mislocalized pdsm phosphomimic preferred reveals s199d stoichiometric sumo sumoylation suppressors	biomarker clinicopathologic confidence depth endometrial federation gynecology hazards histological international interval invasion lymphatic metastasis myometrial node obstetrics organizer overexpressed parameter predicting prognostic rich serve serves special treating untreated worse
Tagcloud (Intersection) ?