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PIAS4 and PDE4DIP
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
PIAS4
PDE4DIP
Gene Name
protein inhibitor of activated STAT, 4
phosphodiesterase 4D interacting protein
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Matrix
PML Body
Nucleus
Cytoplasm
Golgi Apparatus
Centrosome
Myofibril
Molecular Function
DNA Binding
Protein Binding
Zinc Ion Binding
Ligase Activity
SUMO Transferase Activity
Ubiquitin Protein Ligase Binding
SUMO Ligase Activity
Protein Binding
Enzyme Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Wnt Signaling Pathway
Protein Sumoylation
Negative Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Protein Sumoylation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Keratinocyte Apoptotic Process
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Cellular Protein Complex Assembly
Pathways
Drugs
Diseases
GWAS
Capecitabine sensitivity (
22864933
)
Protein-Protein Interactions
75 interactors:
ACTN1
ALDOA
AR
BARD1
BRCA1
BTAF1
CALCOCO2
CEBPD
CHD3
CLK1
COIL
ESRRA
FTH1
GADD45G
HDAC1
HDAC2
HNF4A
HNRNPUL1
HTT
IL15RA
IMMT
IMPDH2
IRF3
IRF7
KPNB1
KRT18
LAMP2
LEF1
LRIF1
MAGEH1
MAP1LC3A
MDC1
MPRIP
NEFL
NR4A2
OAZ1
OPTN
PARP1
PDE4A
PDE4D
PDE4DIP
PHF11
PHGDH
PIAS1
PIAS2
PLAG1
PRPF40A
PTN
RIF1
SATB1
SERBP1
SERPINA5
SETDB1
SH3GL3
SKIL
SMAD1
SMAD2
SMAD3
SMAD4
SMAD7
SNIP1
SUMO1
SUMO2
SUMO3
TADA3
TCERG1
TICAM1
TP53
TRIM27
TRIM32
UBE2I
UBE2K
VIM
ZHX1
ZNF512B
64 interactors:
ADH1B
AEN
ANKRD11
ARNT2
BYSL
C14orf105
C19orf66
C1orf109
CCDC146
CDC5L
CDKN1A
CHCHD3
FAM161A
FAM74A4
FCHSD2
FES
FHL1
GADD45G
GFI1B
GOLGA8EP
GOLGA8F
HAUS1
IMMT
ITSN2
KDM1A
KLC3
KLC4
KRAS
KRT18
KRT31
LAMTOR3
LENG1
LMO4
MAPRE1
MIF4GD
MTUS2
NAA10
NEFL
NEK2
OSGEP
PDE4D
PFDN1
PIAS4
PPP1R18
PRNP
PRPF31
RTP5
SCNM1
SDCBP
SH2D4A
SMN1
SNCA
TFIP11
TK1
TNIK
TRAF4
UTP14C
VAC14
ZBTB38
ZFYVE21
ZNF408
ZNF512B
ZNF581
ZSCAN26
Entrez ID
51588
9659
HPRD ID
06910
10482
Ensembl ID
ENSG00000178104
Uniprot IDs
Q8N2W9
F8WAP3
Q5VU43
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Gene Expression
Regulation Of Metabolic Process
Regulation Of Gene Expression
Cellular Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Biosynthetic Process
Heterocycle Metabolic Process
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Nucleic Acid-templated Transcription
Cellular Response To Organic Substance
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Transcription From RNA Polymerase II Promoter
RNA Metabolic Process
Regulation Of Transcription, DNA-templated
Response To Organic Substance
Regulation Of Cellular Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Response To Stimulus
Positive Regulation Of Gene Expression
Protein Sumoylation
DNA-templated Transcription, Initiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Macromolecule Biosynthetic Process
Cellular Response To Organic Cyclic Compound
Positive Regulation Of Transcription, DNA-templated
Transforming Growth Factor Beta Receptor Signaling Pathway
Response To Stress
Macromolecule Biosynthetic Process
Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Intracellular Receptor Signaling Pathway
Positive Regulation Of Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Cellular Response To Transforming Growth Factor Beta Stimulus
Positive Regulation Of Cellular Metabolic Process
Response To Transforming Growth Factor Beta
Regulation Of Cell Death
Developmental Process
Response To Copper Ion
RNA Metabolic Process
Anatomical Structure Development
Nucleobase-containing Compound Metabolic Process
Regulation Of Microtubule Polymerization
Multicellular Organismal Development
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Response To Copper Ion
Response To Mineralocorticoid
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of JNK Cascade
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Regulation Of Apoptotic Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Microtubule Cytoskeleton Organization
Regulation Of Cell Death
Regulation Of Phosphorylation
Response To Glucocorticoid
Regulation Of JNK Cascade
Activation Of MAPKK Activity
Positive Regulation Of Protein Kinase Activity
Nitrogen Compound Metabolic Process
Response To Corticosteroid
Regulation Of Metabolic Process
Regulation Of Microtubule-based Process
Negative Regulation Of Microtubule Polymerization
Negative Regulation Of Protein Phosphorylation
Positive Regulation Of Kinase Activity
Regulation Of Microtubule Polymerization Or Depolymerization
Cellular Response To Epinephrine Stimulus
Regulation Of Cellular Component Organization
System Development
Regulation Of Stress-activated MAPK Cascade
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Regulation Of Cellular Protein Metabolic Process
Response To Epinephrine
RNA Splicing
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Cell Death
Positive Regulation Of Transferase Activity
Regulation Of Histone H3-K4 Methylation
Regulation Of Kinase Activity
Embryo Development Ending In Birth Or Egg Hatching
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Positive Regulation Of Intracellular Signal Transduction
Tagcloud
?
acceptor
acetyltransferase
alignment
consensus
consequently
deacetylase
dgcr8
e195a
e3
ing
ing1
ing1b
ing2
ing3
ings
isg15
k193
ligase
marks
mislocalized
pdsm
phosphomimic
preferred
reveals
s199d
stoichiometric
sumo
sumoylation
suppressors
Tagcloud (Difference)
?
acceptor
acetyltransferase
alignment
consensus
consequently
deacetylase
dgcr8
e195a
e3
ing
ing1
ing1b
ing2
ing3
ings
isg15
k193
ligase
marks
mislocalized
pdsm
phosphomimic
preferred
reveals
s199d
stoichiometric
sumo
sumoylation
suppressors
Tagcloud (Intersection)
?