PIAS4 and MAGEH1

Number of citations of the paper that reports this interaction (PMID 15383276)
99

Data Source:
HPRD (two hybrid)

		PIAS4	MAGEH1
Gene Name		protein inhibitor of activated STAT, 4	melanoma antigen family H, 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix PML Body	Cytoplasm
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Ligase Activity SUMO Transferase Activity Ubiquitin Protein Ligase Binding SUMO Ligase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Wnt Signaling Pathway Protein Sumoylation Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Protein Sumoylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Keratinocyte Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		75 interactors: ACTN1 ALDOA AR BARD1 BRCA1 BTAF1 CALCOCO2 CEBPD CHD3 CLK1 COIL ESRRA FTH1 GADD45G HDAC1 HDAC2 HNF4A HNRNPUL1 HTT IL15RA IMMT IMPDH2 IRF3 IRF7 KPNB1 KRT18 LAMP2 LEF1 LRIF1 MAGEH1 MAP1LC3A MDC1 MPRIP NEFL NR4A2 OAZ1 OPTN PARP1 PDE4A PDE4D PDE4DIP PHF11 PHGDH PIAS1 PIAS2 PLAG1 PRPF40A PTN RIF1 SATB1 SERBP1 SERPINA5 SETDB1 SH3GL3 SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 SNIP1 SUMO1 SUMO2 SUMO3 TADA3 TCERG1 TICAM1 TP53 TRIM27 TRIM32 UBE2I UBE2K VIM ZHX1 ZNF512B	14 interactors: APP CDK5RAP2 ELN HMBOX1 KPNA2 MOAP1 NAP1L5 NGFR PIAS4 TADA3 TNFRSF1A TNIP1 TRIM41 ZSCAN9
Entrez ID		51588	28986
HPRD ID		06910	06633
Ensembl ID			ENSG00000187601
Uniprot IDs		Q8N2W9	Q9H213
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Cellular Response To Organic Substance Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription, DNA-templated Response To Organic Substance Regulation Of Cellular Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Gene Expression Response To Stimulus Positive Regulation Of Gene Expression Protein Sumoylation DNA-templated Transcription, Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Cellular Response To Organic Cyclic Compound Positive Regulation Of Transcription, DNA-templated Transforming Growth Factor Beta Receptor Signaling Pathway Response To Stress Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Cellular Metabolic Process Response To Transforming Growth Factor Beta Regulation Of Cell Death	Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Neuron Differentiation Positive Regulation Of Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Neurogenesis Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Negative Regulation Of Cell Development Apoptotic Signaling Pathway Regulation Of Transcription, DNA-templated Synaptic Growth At Neuromuscular Junction Positive Regulation Of Keratinocyte Apoptotic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Inflammatory Response Regulation Of RNA Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Organelle Organization Positive Regulation Of Metabolic Process Extrinsic Apoptotic Signaling Pathway Collateral Sprouting In Absence Of Injury Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Hair Follicle Development Apoptotic Process Programmed Cell Death Regulation Of Tubulin Deacetylation Negative Regulation Of Centriole Replication Protein Insertion Into Mitochondrial Membrane Negative Regulation Of Hair Cycle Positive Regulation Of Odontogenesis Of Dentin-containing Tooth Regulation Of Metabolic Process Cell Death Death Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Neuron Differentiation Regulation Of Cellular Component Organization Axon Choice Point Recognition Establishment Of Localization In Cell
Tagcloud ?		acceptor acetyltransferase alignment consensus consequently deacetylase dgcr8 e195a e3 ing ing1 ing1b ing2 ing3 ings isg15 k193 ligase marks mislocalized pdsm phosphomimic preferred reveals s199d stoichiometric sumo sumoylation suppressors
Tagcloud (Difference) ?		acceptor acetyltransferase alignment consensus consequently deacetylase dgcr8 e195a e3 ing ing1 ing1b ing2 ing3 ings isg15 k193 ligase marks mislocalized pdsm phosphomimic preferred reveals s199d stoichiometric sumo sumoylation suppressors
Tagcloud (Intersection) ?