MDC1 and TP53BP1

  • Number of citations of the paper that reports this interaction (PMID 12607005)
  • 193
  • Data Source:
  • HPRD (in vivo)

MDC1

TP53BP1

Gene Name mediator of DNA-damage checkpoint 1 tumor protein p53 binding protein 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 37 interactors: ANAPC1 ATM BARD1 BRCA1 CASP3 CENPC CHEK2 COPS5 CREBBP CSNK2A1 DTX2 EP300 GATA4 H2AFX HDAC10 HDAC8 HINFP LOC729324 NBN NCL PIAS1 PIAS4 PRIM1 RAD50 RAD51 RNF8 SMC1A SUMO1 SUMO2 TP53 TP53BP1 UIMC1 USP28 VAMP5 WHSC1 WRN ZNF251 34 interactors: ARAP1 ATM BLM BRCA1 CCNB1 CDK1 CRB2 DCLRE1A DCLRE1C DYNLL1 E2F1 EP300 GALNTL5 H2AFX HIST1H4A HIST2H4A HIST4H4 IFI16 LIG4 MDC1 MEOX2 NCOA3 NEK1 NFKB1 PAXIP1 PCNT PLK1 RAD18 RELA SPAG9 TFDP1 TP53 USP28 VAC14
Entrez ID 9656 7158
HPRD ID 16252 05569
Ensembl ID ENSG00000137337 ENSG00000067369
Uniprot IDs A1Z5I9 Q14676 F8VY86 Q12888
PDB IDs 2ADO 2AZM 2ETX 3K05 3UEO 3UMZ 3UN0 3UNM 3UNN 3UOT 1GZH 1KZY 1XNI 2G3R 2IG0 2LVM 3LGF 3LGL 3LH0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  rad51  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
abstract  adenocarcinoma  bonferroni  carcinogenesis  cardia  cc  confirm  correction  ga  gc  gca  genotype  genotypes  ldr  ligation  needed  nucleotide  p21  p73  polymorphisms  remained  remaining  replication  rs1059234  rs3176352  rs560191  rs762623  snps  tt 
Tagcloud (Difference) ?
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  rad51  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
abstract  adenocarcinoma  bonferroni  carcinogenesis  cardia  cc  confirm  correction  ga  gc  gca  genotype  genotypes  ldr  ligation  needed  nucleotide  p21  p73  polymorphisms  remained  remaining  replication  rs1059234  rs3176352  rs560191  rs762623  snps  tt 
Tagcloud (Intersection) ?