MDC1 and SUMO2

  • Number of citations of the paper that reports this interaction (PMID 19471022)
  • 89
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study)

MDC1

SUMO2

Gene Name mediator of DNA-damage checkpoint 1 small ubiquitin-like modifier 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 37 interactors: ANAPC1 ATM BARD1 BRCA1 CASP3 CENPC CHEK2 COPS5 CREBBP CSNK2A1 DTX2 EP300 GATA4 H2AFX HDAC10 HDAC8 HINFP LOC729324 NBN NCL PIAS1 PIAS4 PRIM1 RAD50 RAD51 RNF8 SMC1A SUMO1 SUMO2 TP53 TP53BP1 UIMC1 USP28 VAMP5 WHSC1 WRN ZNF251 91 interactors: ALAS1 ARL13A ARNTL ATXN1 ATXN7 AURKB BAD BCL11A BLM BRCC3 BRE C18orf25 CCNE2 CDCA8 CENPC CHAF1A CHD3 CMTM6 CORO2A CSNK2B CUL3 FAM175A FOS HDAC4 HDAC9 HIF1A HIPK2 HNF4A HOMEZ HSF2 JUN KALRN KDM1A KRT14 KRT5 KRT8 LEF1 MAF1 MAST2 MDC1 MSX1 MYB NFKBIA PARP1 PIAS1 PIAS2 PIAS3 PIAS4 PML RAC1 RANGAP1 RB1 RNF111 RNF4 SAE1 SENP1 SENP2 SENP3 SENP5 SENP6 SENP7 SETDB1 SETX SH3KBP1 SLC22A2 SNCA SOX10 SOX6 SP100 STK24 SUMO1 TDG TDP2 TEAD3 TNIP1 TOPORS TP53BP2 TRIM63 UBA2 UBE2I USP25 USPL1 VIM WRN XPC ZBTB1 ZCCHC12 ZCCHC7 ZHX1 ZMYM2 ZMYM5
Entrez ID 9656 6613
HPRD ID 16252 04332
Ensembl ID ENSG00000137337 ENSG00000188612
Uniprot IDs A1Z5I9 Q14676 P61956
PDB IDs 2ADO 2AZM 2ETX 3K05 3UEO 3UMZ 3UN0 3UNM 3UNN 3UOT 1WM2 1WM3 1WZ0 1Z5Q 2AWT 2CKH 2D07 2IO0 2IO3 2IYD 2RPQ 3UIN 3UIO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  rad51  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
augment  consequent  delaying  elusive  emerged  enhance  enhancing  facilitates  fasting  fate  linking  maintenance  melanoma  modifications  modified  node  nutrient  partner  promising  relief  rev1  sensing  short  specialized  starvation  suppressor  therapies  toxic  turn 
Tagcloud (Difference) ?
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  premature  rad51  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
augment  consequent  delaying  elusive  emerged  enhance  enhancing  fasting  fate  linking  maintenance  melanoma  modifications  modified  node  nutrient  promising  relief  rev1  sensing  short  specialized  starvation  suppressor  therapies  toxic  turn 
Tagcloud (Intersection) ?
facilitates  partner