MDC1 and RAD51

  • Number of citations of the paper that reports this interaction (PMID 16186822)
  • 29

MDC1

RAD51

Gene Name mediator of DNA-damage checkpoint 1 RAD51 recombinase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 37 interactors: ANAPC1 ATM BARD1 BRCA1 CASP3 CENPC CHEK2 COPS5 CREBBP CSNK2A1 DTX2 EP300 GATA4 H2AFX HDAC10 HDAC8 HINFP LOC729324 NBN NCL PIAS1 PIAS4 PRIM1 RAD50 RAD51 RNF8 SMC1A SUMO1 SUMO2 TP53 TP53BP1 UIMC1 USP28 VAMP5 WHSC1 WRN ZNF251 42 interactors: ABL1 ATM ATRX BCCIP BLM BRCA1 BRCA2 CASP3 CASP7 CHD3 CHEK1 DMC1 DNAJA3 ERCC2 FANCD2 FBXO18 HID1 HNRNPC IRS1 MDC1 NXF1 PFN1 RAD18 RAD51AP1 RAD51AP2 RAD51C RAD52 RAD54B RAD54L RPA1 RPA3 SFR1 SUMO1 SWI5 SWSAP1 TP53 UBE2I UGDH UHRF2 VIM WRN ZDHHC17
Entrez ID 9656 5888
HPRD ID 16252 01557
Ensembl ID ENSG00000137337 ENSG00000051180
Uniprot IDs A1Z5I9 Q14676 Q06609
PDB IDs 2ADO 2AZM 2ETX 3K05 3UEO 3UMZ 3UN0 3UNM 3UNN 3UOT 1B22 1N0W
Enriched GO Terms of Interacting Partners?
Tagcloud ?
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  rad51  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
boundary  box  cerevisiae  consisting  damaging  declined  delta  dosage  dsc1  elements  enhances  fluctuate  fluctuation  frequency  mbf1  mbp1  mcb  meiosis  meiotic  mitotic  mlu  rad54  recombination  saccharomyces  spore  sporulation  swi6  transcript  viability 
Tagcloud (Difference) ?
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
boundary  box  cerevisiae  consisting  damaging  declined  delta  dosage  dsc1  elements  enhances  fluctuate  fluctuation  frequency  mbf1  mbp1  mcb  meiosis  meiotic  mitotic  mlu  rad54  recombination  saccharomyces  spore  sporulation  swi6  transcript  viability 
Tagcloud (Intersection) ?
rad51