CCDC33 and ING5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		CCDC33	ING5
Description		coiled-coil domain containing 33	inhibitor of growth family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Protein Binding	Chromatin Binding Protein Binding Zinc Ion Binding Metal Ion Binding Histone H3K4me3 Reader Activity
	Biological Process		Regulation Of Cell Growth Regulation Of DNA Replication Chromatin Organization Regulation Of DNA-templated Transcription Protein Acetylation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Negative Regulation Of Growth Fibroblast Proliferation Negative Regulation Of Fibroblast Proliferation Regulation Of Developmental Process Regulation Of Cell Cycle Apoptotic Signaling Pathway DNA Replication-dependent Chromatin Disassembly Regulation Of Hemopoiesis Regulation Of DNA Biosynthetic Process Positive Regulation Of Apoptotic Signaling Pathway
Pathways			HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS		Bacterial meningitis ( 31092817) Coffee consumption (cups per day) ( 31837886) Craniofacial microsomia ( 26853712) Diastolic blood pressure ( 30224653) Diisocyanate-induced asthma ( 25918132) Hip circumference adjusted for BMI ( 34021172) Obesity-related traits ( 23251661) Systolic blood pressure ( 30578418)	Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494)
Interacting Genes		159 interacting genes: ABCF3 ABLIM3 AIRIM ANKS1A AP1M1 APP ARHGEF6 ARIH2 ARMC7 ARNT2 ATOSB BCCIP BLK BLZF1 BYSL CABP2 CALCOCO2 CCDC102B CCDC57 CCDC6 CCDC85B CCHCR1 CCNH CDC23 CDCA7L CDKN2B CENPP CFAP206 CHCHD3 CINP CIRSR CRYBA2 CRYBA4 CTNNA3 DGCR6 DIP2A DVL2 DVL3 EAF1 EFEMP2 EHMT2 EMC2 EMD ESRRG EXOC8 FAM124A FAM161A FRS3 FXR2 GCC1 GPANK1 GPATCH2L GRN GYS1 HEXIM2 HGS HNRNPF HNRNPK HOOK2 HOXA1 HSF2BP IL16 ING5 ITGB1BP1 KANK2 KCTD19 KCTD9 KDM1A KHDRBS3 KIFC3 KLHL38 KXD1 L3MBTL2 LDOC1 LMO1 LMO2 LMO3 LNX1 MAGED1 MAGOHB MAPK9 MDFI MFAP1 MID2 MIPOL1 MISP MKRN3 MLH1 MOS NAB2 NCK2 NDOR1 NECAB2 NEFL NINL NME7 OSGIN1 OSTF1 PCSK5 PID1 PIK3R3 PIN1 PLA2G6 PLSCR1 PNMA1 PNMA2 POLR1C PPP2R3C PRKAA2 PRKAB2 PRPF31 PTGER3 PTK6 QARS1 RAD51D RAD54B RBMX RHOXF2 RNF6 SCNM1 SMAD3 SMARCB1 SMARCD1 SMYD1 SPAG5 SPG21 STK16 STX11 SYT17 TASOR2 TCEANC TGFB1 TMCC2 TNS2 TRAF2 TRIM23 TRIM37 TRIM42 TRIM59 TSC22D4 TSEN15 TSGA10 TTC19 TUFT1 TXK TXLNA UBASH3A UBQLN4 USHBP1 VPS52 WT1 YES1 ZBTB8A ZGPAT ZNF330 ZNF572 ZNF688 ZNF76 ZNRD2	45 interacting genes: APC APLP1 ARFIP2 BARD1 BEX3 C3orf62 CBY2 CCDC33 CCHCR1 CDCA7L CDK2 CDKN1A CEP126 CEP44 DEUP1 EP300 FAM118B GCSH GGA1 GRIPAP1 HAP1 HGS HTT ICA1 IKZF3 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 ODF2 PCM1 PRMT5 RCOR3 SMARCE1 SUOX TADA3 TAF1D THAP6 TP53 TRIML2 VIM WASF1
Entrez ID		80125	84289
HPRD ID		09959	16348
Ensembl ID		ENSG00000140481	ENSG00000168395
Uniprot IDs		A0A1B0GV97 Q8N5R6	A0A1B0GW41 Q8WYH8
PDB IDs			3C6W 5ME8 5MTO
Enriched GO Terms of Interacting Partners?		Protein Binding Identical Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleoplasm Cytoplasm Non-membrane Spanning Protein Tyrosine Kinase Activity Regulation Of Macromolecule Biosynthetic Process CD4 Receptor Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of Primary Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Neuron Maturation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Speck Spliceosomal Complex Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Enzyme Binding	Identical Protein Binding Centriole Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Mitotic G1 DNA Damage Checkpoint Signaling Mitotic G1/S Transition Checkpoint Signaling Protein Binding Cytosol Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Protein Domain Specific Binding Negative Regulation Of Cell Cycle G1/S Phase Transition Centriole Replication P53 Binding Membrane Curvature Sensor Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Microtubule Organizing Center Organization Centriole Assembly Organelle Transport Along Microtubule Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Transport Along Microtubule Regulation Of Cell Cycle G1/S Phase Transition Stress-induced Premature Senescence Protein-containing Complex Cytoskeleton-dependent Intracellular Transport Intracellular Transport Regulation Of Organelle Organization Microtubule-based Process Negative Regulation Of Mitotic Cell Cycle Nuclear Receptor Binding Neurogenesis Regulation Of Mitotic Cell Cycle Phase Transition Centrosome Regulation Of DNA Metabolic Process Regulation Of Cell Cycle G2/M Phase Transition Regulation Of DNA Replication Microtubule-based Transport Negative Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Negative Regulation Of Cyclin-dependent Protein Kinase Activity Nucleoplasm Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Centriole-centriole Cohesion Regulation Of Intracellular Protein Transport ATAC Complex Cellular Senescence Regulation Of Intracellular Transport Small GTPase-mediated Signal Transduction Establishment Of Organelle Localization Replicative Senescence
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