PIR

Description		pirin
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body
	Molecular Function	Transcription Coregulator Activity Protein Binding Quercetin 2,3-dioxygenase Activity Oxidoreductase Activity Metal Ion Binding Dioxygenase Activity
	Biological Process	Transcription By RNA Polymerase II Digestion Myeloid Cell Differentiation Monocyte Differentiation
Pathways		Digestion
Drugs
Diseases
GWAS
Interacting Genes		4 interacting genes: BCL3 NFIX NFKBIA SMAD9
Entrez ID		8544
HPRD ID		04510
Ensembl ID		ENSG00000087842
Uniprot IDs		O00625
PDB IDs		1J1L 3ACL 4ERO 4EWA 4EWD 4EWE 4GUL 4HLT 5JCT 6H1H 6H1I 6N0J 6N0K
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Canonical NF-kappaB Signal Transduction Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Bcl3-Bcl10 Complex Protein Import Into Nucleus Import Into Nucleus Bcl3/NF-kappaB2 Complex Intracellular Signaling Cassette Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Follicular Dendritic Cell Differentiation Positive Regulation Of Biosynthetic Process Regulation Of DNA-binding Transcription Factor Activity Protein Localization To Nucleus Follicular Dendritic Cell Activation I-kappaB/NF-kappaB Complex Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of RNA Biosynthetic Process Nuclear Transport Nucleocytoplasmic Transport Positive Regulation Of Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process SMAD Protein Complex Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Heteromeric SMAD Protein Complex Germinal Center Formation Regulation Of Nucleobase-containing Compound Metabolic Process T-helper 2 Cell Differentiation Negative Regulation Of RNA Metabolic Process Marginal Zone B Cell Differentiation Negative Regulation Of Cytokine Production T-helper 1 Type Immune Response Establishment Of Protein Localization To Organelle Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Negative Regulation Of Macrophage Derived Foam Cell Differentiation Response To UV-C Cellular Response To Cold I-SMAD Binding Intracellular Signal Transduction Negative Regulation Of Protein Import Into Nucleus
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