ARHGAP9

Description		Rho GTPase activating protein 9
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Plasma Membrane Secretory Granule Lumen
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Lipid Binding
	Biological Process	Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Neutrophil degranulation RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494)
Interacting Genes		17 interacting genes: ABI3 AKT1 APP CYSRT1 FASLG FHL2 GOLGA6A GOLGA6L9 HOMEZ MRPL38 NME7 RAC1 RBPMS RUNX1T1 SMAD9 SNRPC TSC22D4
Entrez ID		64333
HPRD ID		06449
Ensembl ID		ENSG00000123329
Uniprot IDs		B3KQ74 Q9BRR9
PDB IDs		2P0D 2P0F 2P0H
Enriched GO Terms of Interacting Partners?		Regulation Of Postsynapse Organization Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Postsynapse Sphingosine-1-phosphate Receptor Signaling Pathway Sphingolipid Mediated Signaling Pathway Regulation Of Synapse Organization Osteoblast Differentiation Response To Growth Factor SMAD Protein Signal Transduction Regulation Of Extrinsic Apoptotic Signaling Pathway Lymphocyte Apoptotic Process T Cell Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Toll-like Receptor Signaling Pathway Lamellipodium Regulation Of Fibroblast Migration Response To Nerve Growth Factor Regulation Of Protein Localization To Membrane Regulation Of TRNA Methylation Positive Regulation Of Nitric Oxide Metabolic Process Cellular Response To Nerve Growth Factor Stimulus Amyloid-beta Complex Dendritic Shaft Regulation Of Synapse Assembly Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Dendrite Development Regulation Of Ruffle Assembly Regulation Of Lamellipodium Assembly Leukocyte Apoptotic Process Homeostatic Process Chemical Homeostasis Intracellular Signaling Cassette Negative Regulation Of Protein Localization Regulation Of Lamellipodium Organization Regulation Of Neuron Apoptotic Process Regulation Of Leukocyte Migration Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cell Projection Assembly Negative Regulation Of RNA Metabolic Process Response To Peptide Response To Cytokine Negative Regulation Of Protein Localization To Lysosome Acetylcholine Receptor Activator Activity Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
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