FLI1 and SOX30

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FLI1	SOX30
Gene Name		Fli-1 proto-oncogene, ETS transcription factor	SRY (sex determining region Y)-box 30
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Hemostasis Blood Circulation Organ Morphogenesis Cell Differentiation Megakaryocyte Development Positive Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Spermatogenesis Response To Corticosteroid
Pathways
Drugs
Diseases
GWAS		Height ( 20881960) Myopia (pathological) ( 23049088) Rheumatoid arthritis ( 22446963)
Protein-Protein Interactions		19 interactors: BRCA1 CTBP2 ELK1 ERG ETV6 EWSR1 GATA1 KLF1 PIAS1 PIAS2 PRKCD SIAH1 SMAD3 SMAD9 SOX30 SRF SUMO1 TDP2 UBE2I	16 interactors: AHCYL1 BAMBI BRCA1 C6orf165 CUL5 DCAF4 DDX56 FBXO38 FLI1 GNAI3 GP2 KIFC3 NME1 NUDT3 PAXIP1 TRAF2
Entrez ID		2313	11063
HPRD ID		01901	09461
Ensembl ID		ENSG00000151702	ENSG00000039600
Uniprot IDs		Q01543	B4DXW7 O94993
PDB IDs		1FLI 1X66 2YTU
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Heterocycle Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Protein Sumoylation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Response To Organic Substance Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Organic Substance Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Binding Regulation Of Cellular Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Androgen Receptor Signaling Pathway Regulation Of Signaling Erythrocyte Development Protein Modification By Small Protein Conjugation Regulation Of Signal Transduction Intracellular Steroid Hormone Receptor Signaling Pathway Developmental Process Metabolic Process Peptidyl-lysine Modification Peptidyl-amino Acid Modification	Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Binding Positive Regulation Of Histone Acetylation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Positive Regulation Of Histone Methylation Protein Ubiquitination Protein Autoubiquitination Regulation Of Histone Acetylation Protein Modification By Small Protein Conjugation Regulation Of Histone Methylation Regulation Of Binding Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H3-K36 Methylation Antigen Transcytosis By M Cells In Mucosal-associated Lymphoid Tissue Positive Regulation Of Histone H4-K16 Acetylation Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Positive Regulation Of Protein Binding Positive Regulation Of Histone Modification DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Histone H3-K9 Acetylation Signal Transduction In Response To DNA Damage Cellular Response To Tumor Necrosis Factor Zonula Adherens Maintenance Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Signal Transduction By P53 Class Mediator Regulation Of Histone Modification Response To Tumor Necrosis Factor Positive Regulation Of Protein Ubiquitination S-adenosylmethionine Cycle Cellular Response To Indole-3-methanol Response To Ionizing Radiation Regulation Of Protein Binding Positive Regulation Of DNA Metabolic Process Negative Regulation Of Centriole Replication Positive Regulation Of Adaptive Immune Response Dosage Compensation By Inactivation Of X Chromosome Negative Regulation Of Glial Cell Apoptotic Process Protein Polyubiquitination Protein K6-linked Ubiquitination Chorion Development Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Intrinsic Apoptotic Signaling Pathway Nucleobase-containing Small Molecule Metabolic Process
Tagcloud ?		antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed	activating advance antitumorigenic attenuates blockade box cactttg doi ectopic harboring hypermethylated hypermethylation indeed lung methylated onc oncogene online peri preferentially publication represses silence silenced sry tumoral unexplored unmethylated
Tagcloud (Difference) ?		antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed	activating advance antitumorigenic attenuates blockade box cactttg doi ectopic harboring hypermethylated hypermethylation indeed lung methylated onc oncogene online peri preferentially publication represses silence silenced sry tumoral unexplored unmethylated
Tagcloud (Intersection) ?