ZSCAN4 and FAM110A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZSCAN4	FAM110A
Description		zinc finger and SCAN domain containing 4	family with sequence similarity 110 member A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Chromosome	Spindle Pole Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Spindle Microtubule Cell Cortex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Mitotic Recombination	Mitotic Spindle Organization
Pathways		Zygotic genome activation (ZGA)
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Prostate cancer ( 31562322)
Interacting Genes		13 interacting genes: CIB3 CTBP2 EXOC8 FAM110A HAT1 HCK KAT5 LAMTOR3 PARD6B SMAD1 SMAD9 TBC1D22B TRAF3	52 interacting genes: AGR2 BICD2 CCNDBP1 CDR2 COG4 COG6 CSNK1E CTDSP1 CTNNA3 DYNC1I1 EFEMP1 EFEMP2 FHL3 FSD2 GOLGA2 GOLGA6L9 HOOK2 HSF2BP KRT15 KRT27 KRT31 KRT34 KRT37 KRT38 KRT39 KRTAP10-8 LDOC1 LIX1 MEIS3 MIF4GD MKRN3 MTUS2 MYOG PFDN5 PNMA1 PYGM RASSF10 RASSF3 RCN1 RINT1 ROPN1 STX11 TCF4 TRIM23 TRIM27 TRIM54 TRIM69 TSC1 TSG101 USHBP1 VPS52 ZSCAN4
Entrez ID		201516	83541
HPRD ID		15899	12775
Ensembl ID		ENSG00000180532	ENSG00000125898
Uniprot IDs		Q8NAM6	Q9BQ89
PDB IDs
Enriched GO Terms of Interacting Partners?		Heteromeric SMAD Protein Complex SMAD Protein Complex Histone H4 Acetyltransferase Activity I-SMAD Binding SMAD Protein Signal Transduction Protein-lysine-acetyltransferase Activity Innate Immune Response-activating Signaling Pathway Histone Acetyltransferase Activity Protein Acetylation Activation Of Innate Immune Response Transcription Regulator Complex Histone H2AK5 Acetyltransferase Activity	Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Structural Molecule Activity Supramolecular Fiber Organization Epithelial Cell Differentiation Protein Binding Tissue Morphogenesis Morphogenesis Of An Epithelium Vesicle-mediated Transport Cytoskeleton Organization Golgi Vesicle Transport Organelle Organization Retrograde Transport, Vesicle Recycling Within Golgi Golgi Transport Complex Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule
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