SMAD6 and MAPK6

  • Number of citations of the paper that reports this interaction (PMID 21900206)
  • 27
  • Data Source:
  • BioGRID (two hybrid)

SMAD6

MAPK6

Gene Name SMAD family member 6 mitogen-activated protein kinase 6
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions 16 interactors: BMPR1B HOXC8 MAP3K7 MAPK6 RNF111 RPS6KA5 RUNX2 SMAD1 SMAD7 SMURF1 SMURF2 STAMBP STRAP TAB1 TGFBR1 TOB1 167 interactors: ACTG1 ACTR1B AMPH ANAPC5 ANK3 APBA2 APOA1 APOA1BP ARHGDIA ARPC3 ATG9A ATP5J BAG6 BARX1 BBS10 C21orf59 CA1 CA12 CALR CASP6 CCND3 CCT3 CDH13 CERS1 CFL1 CNTN1 CNTRL COPS6 CSE1L CYTH2 DBN1 DCTN2 DDOST DDR1 DGKZ DKC1 DNAJC28 DPPA4 DSCR3 DST EDF1 EEF1A2 EGLN3 EIF1 EIF3C EIF4A1 ELOF1 EMD FAM49B FBXL16 FOXO3 FXYD3 GALNT7 GATA1 GLRX3 GNB2L1 GORASP1 GPX1 HACL1 HAUS2 HDAC11 HIP1 HNRNPA0 HNRNPD HNRNPH3 HSP90AB1 HSP90B1 HSPD1 IDH3B INS ITGB3BP ITSN1 JUNB KDSR KLC1 KNSTRN LPXN MAP3K12 MAP3K7 MAPKAPK5 MASP1 MBIP MBOAT7 MCM3 MDK METTL17 METTL2A MGAT1 MIPEP MOK MON1A MTG2 MYBL2 MYOZ3 MZB1 NAT9 NDUFS6 NELFB NOL4 NRXN2 NUDT5 OSTF1 PDCD6IP PDLIM1 PHACTR3 PHC2 PHGDH PIH1D1 PLEKHM1 PLK1 PLSCR1 PPBP PPP1R7 PPP2R1A PRKAB1 PRKAR1A PRKCB PRPF38A PSAT1 PSIP1 PTPMT1 PVRL2 RAB2A RAB31 RANBP9 RAP1GAP RARA RBL1 RGS19 RPL10 RRP7A SEPT3 SEPT5 SERPINA4 SHC1 SLC20A1 SLC41A3 SMAD6 SMS SNAPC4 SNW1 SOCS3 SPG7 SPRR2D SPTAN1 SRSF5 STX7 TDP2 THAP4 TPI1 TTK TUBA1A UBA52 UBE2L3 URB1 WDR26 WDR34 WFS1 WWC1 XPO1 ZNF133 ZNF205 ZNF331 ZNF579 ZNF600 ZNF671 ZNF775
Entrez ID 4091 5597
HPRD ID 04240 04213
Ensembl ID ENSG00000137834 ENSG00000069956
Uniprot IDs O43541 Q16659
PDB IDs 2I6L
Enriched GO Terms of Interacting Partners?
Tagcloud ?
5fu  annotation  anticancer  array  chemoresistance  concluded  consequently  deacetylases  deacetylation  downregulate  fluorouracil  fu  hdac4  hdac4mediated  hdac4oe  hdacs  mb  mcf7  mda  morphogenetic  overexpressing  remodeling  restored  smad4  stably  summary  tgfbeta2  transforming  verify 
astragalus  barbata  bcm  berry  bioflavonoid  coptis  coriolus  dandelion  diinodolymethane  eleuthero  ganoderma  knotweed  linteus  lucidum  mycelium  nettle  nr2f1  palmetto  phellinus  plau  pomegranate  prostacaid  pumpkin  pygeum  sarsaparilla  scutellaria  sitosterolzinc  skullcap  stinging 
Tagcloud (Difference) ?
5fu  annotation  anticancer  array  chemoresistance  concluded  consequently  deacetylases  deacetylation  downregulate  fluorouracil  fu  hdac4  hdac4mediated  hdac4oe  hdacs  mb  mcf7  mda  morphogenetic  overexpressing  remodeling  restored  smad4  stably  summary  tgfbeta2  transforming  verify 
astragalus  barbata  bcm  berry  bioflavonoid  coptis  coriolus  dandelion  diinodolymethane  eleuthero  ganoderma  knotweed  linteus  lucidum  mycelium  nettle  nr2f1  palmetto  phellinus  plau  pomegranate  prostacaid  pumpkin  pygeum  sarsaparilla  scutellaria  sitosterolzinc  skullcap  stinging 
Tagcloud (Intersection) ?