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MAPK6 and PDCD6IP
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
0
Data Source:
BioGRID
(two hybrid)
MAPK6
PDCD6IP
Description
mitogen-activated protein kinase 6
programmed cell death 6 interacting protein
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Septin Cytoskeleton
Protein-containing Complex
Immunological Synapse
Extracellular Region
Cytoplasm
Endosome
Centrosome
Cytosol
Cytoskeleton
Bicellular Tight Junction
Focal Adhesion
Membrane
Melanosome
Actomyosin
Extracellular Exosome
Anchoring Junction
Endoplasmic Reticulum Exit Site
Flemming Body
Extracellular Vesicle
Molecular Function
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
MAP Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Protein Kinase Binding
Protein Heterodimerization Activity
Protein Serine Kinase Activity
Protein Binding
Proteinase Activated Receptor Binding
Protein Homodimerization Activity
Calcium-dependent Protein Binding
Biological Process
MAPK Cascade
Protein Phosphorylation
Signal Transduction
Intracellular Signal Transduction
Positive Regulation Of Dendritic Spine Development
Mitotic Cytokinesis
Actomyosin Contractile Ring Assembly
Apoptotic Process
Nucleus Organization
Mitotic Metaphase Chromosome Alignment
Regulation Of Centrosome Duplication
Protein Transport
Macroautophagy
Multivesicular Body Assembly
Viral Budding Via Host ESCRT Complex
Maintenance Of Epithelial Cell Apical/basal Polarity
Viral Budding
Protein Homooligomerization
Cell Division
Midbody Abscission
Bicellular Tight Junction Assembly
Regulation Of Membrane Permeability
Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Extracellular Exosome Biogenesis
Regulation Of Mitotic Spindle Assembly
Positive Regulation Of Exosomal Secretion
Regulation Of Extracellular Exosome Assembly
Positive Regulation Of Extracellular Exosome Assembly
Pathways
MAPK6/MAPK4 signaling
Budding and maturation of HIV virion
Uptake and function of anthrax toxins
RIPK1-mediated regulated necrosis
Regulation of necroptotic cell death
Drugs
Acetylsalicylic acid
Minocycline
Colforsin
Diseases
GWAS
Frailty index (
34431594
)
Serum uric acid levels in response to allopurinol in gout (
25676789
)
Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) (
28090653
)
Neuroticism (
27089181
)
Periodontitis (Mean PAL) (
24024966
)
Rosacea symptom severity (
29771307
)
Severe influenza A (H1N1) infection (
26379185
)
Smoking status (ever vs never smokers) (
30643258
)
Visceral adipose tissue adjusted for BMI (
22589738
)
White coat effect (clinic diastolic blood pressure minus ambulatory diastolic blood pressure) (
31044621
)
Interacting Genes
167 interacting genes:
ACTG1
ACTR1B
AMPH
ANAPC5
ANK3
ANKRD2
APBA2
ARHGDIA
ARPC3
ATG9A
ATP5PF
BAG6
BARX1
BBS10
BTRC
CA1
CA12
CALR
CASP6
CCND3
CCT3
CDH13
CERS1
CFAP298
CFL1
CNTN1
CNTRL
COPS6
CSE1L
CYRIB
CYTH2
DBN1
DCTN2
DDOST
DDR1
DGKZ
DKC1
DNAJC28
DPPA4
DST
DYNC2I2
EDF1
EEF1A2
EIF1
EIF3C
EIF4A1
ELOF1
EMD
FBXL16
FOXO3
FXYD3
GALNT7
GATA1
GLRX3
GORASP1
GPX1
HACL1
HAUS2
HDAC11
HIP1
HNRNPA0
HNRNPD
HNRNPH3
HSP90AB1
HSP90B1
HSPD1
IDH3B
INS
ITGB3BP
ITSN1
JUNB
KDSR
KLC1
KNSTRN
LPXN
MAP3K12
MAP3K7
MAPKAPK5
MASP1
MBIP
MBOAT7
MCM3
MDK
METTL17
METTL2A
MGAT1
MIPEP
MOK
MON1A
MTG2
MYBL2
MYOZ3
MZB1
NAT9
NAXE
NDUFS6
NECTIN2
NELFB
NOL4
NRXN2
NUDT5
OSTF1
PDCD6IP
PDLIM1
PHACTR3
PHC2
PHGDH
PIH1D1
PLEKHM1
PLSCR1
PPBP
PPP1R7
PPP2R1A
PRKAB1
PRKAR1A
PRKCB
PRPF38A
PSAT1
PSIP1
PTPMT1
RAB2A
RAB31
RACK1
RANBP9
RAP1GAP
RARA
RBL1
RGS19
RPL10
RRP7A
SEPTIN3
SEPTIN5
SERPINA4
SHC1
SLC20A1
SLC41A3
SMAD6
SMS
SNAPC4
SNW1
SOCS3
SPG7
SPRR2D
SPTAN1
SRSF5
STX7
TDP2
THAP4
TPI1
TTK
TUBA1A
UBA52
UBE2L3
URB1
USP20
VPS26C
WDR26
WFS1
WWC1
XPO1
ZNF133
ZNF205
ZNF331
ZNF579
ZNF600
ZNF671
ZNF775
43 interacting genes:
ARRDC1
ARRDC3
ATN1
CD2AP
CEP55
CHMP4A
CHMP4B
CHMP4C
CXCR1
DRD1
EGFR
F2R
GRB2
ITSN1
ITSN2
KEAP1
LRRN1
MAPK6
NEDD4L
NEURL2
NUP155
PDCD6
PTK2B
RAMP3
RNF10
RNF11
SDCBP
SDCBP2
SH3GL1
SH3GL2
SH3GL3
SH3KBP1
SH3RF1
SNCA
SRC
SUMO2
TAB1
TSG101
TTF2
VPS28
VPS37C
WWP2
YES1
Entrez ID
5597
10015
HPRD ID
04213
06425
Ensembl ID
ENSG00000069956
ENSG00000170248
Uniprot IDs
Q16659
Q8WUM4
PDB IDs
6YKY
6YLC
6YLL
7AQB
2OEV
2OEW
2OEX
2OJQ
2R02
2R03
2R05
2XS1
2XS8
2ZNE
3C3O
3C3Q
3C3R
3E1R
3WUV
4JJY
5V3R
5WA1
6KP3
Enriched GO Terms of Interacting Partners
?
Cytosol
Cytoplasm
Nucleus
Protein Binding
Extracellular Exosome
Ubiquitin Protein Ligase Binding
Endosome
Viral Budding Via Host ESCRT Complex
Viral Budding
Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Vesicle-mediated Transport
Multivesicular Body Assembly
Multivesicular Body Organization
Establishment Of Protein Localization
Late Endosome To Vacuole Transport
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Endosome Transport Via Multivesicular Body Sorting Pathway
Membrane Fission
Multivesicular Body Sorting Pathway
Proteolysis Involved In Protein Catabolic Process
Endocytosis
Protein Transport
Endosome Organization
Cytoplasm
Regulation Of Endocytosis
Multivesicular Body
Macromolecule Catabolic Process
Biological Process Involved In Interaction With Host
Macroautophagy
Endosomal Transport
Receptor-mediated Endocytosis
Import Into Cell
Midbody Abscission
Cellular Localization
Establishment Of Localization In Cell
Regulation Of MAPK Cascade
Regulation Of Caveolin-mediated Endocytosis
Mitotic Cytokinetic Process
Intracellular Transport
Viral Release From Host Cell
Receptor Internalization
Vesicle Organization
Protein Metabolic Process
Positive Regulation Of MAPK Cascade
Viral Process
Late Endosome Membrane
ESCRT I Complex
ESCRT III Complex
Amphisome Membrane
Vesicle Fusion With Vacuole
Plasma Membrane
Synaptic Vesicle Endocytosis
Cytokinetic Process
Regulation Of Organelle Assembly
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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