MAPK6 and GALNT7

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		MAPK6	GALNT7
Description		mitogen-activated protein kinase 6	polypeptide N-acetylgalactosaminyltransferase 7
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Septin Cytoskeleton Protein-containing Complex	Golgi Membrane Golgi Apparatus Membrane Extracellular Exosome
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Kinase Binding Protein Heterodimerization Activity Protein Serine Kinase Activity	Polypeptide N-acetylgalactosaminyltransferase Activity Transferase Activity Glycosyltransferase Activity Carbohydrate Binding Metal Ion Binding
	Biological Process	MAPK Cascade Protein Phosphorylation Signal Transduction Intracellular Signal Transduction Positive Regulation Of Dendritic Spine Development	Carbohydrate Metabolic Process Protein Glycosylation Protein O-linked Glycosylation Protein O-linked Glycosylation Via N-acetyl-galactosamine
Pathways		MAPK6/MAPK4 signaling	O-linked glycosylation of mucins
Drugs		Acetylsalicylic acid Minocycline Colforsin
Diseases
GWAS		Frailty index ( 34431594) Serum uric acid levels in response to allopurinol in gout ( 25676789)	Metabolite levels ( 23823483) Neuritic plaque ( 25188341) Refractive error ( 32231278)
Interacting Genes		167 interacting genes: ACTG1 ACTR1B AMPH ANAPC5 ANK3 ANKRD2 APBA2 ARHGDIA ARPC3 ATG9A ATP5PF BAG6 BARX1 BBS10 BTRC CA1 CA12 CALR CASP6 CCND3 CCT3 CDH13 CERS1 CFAP298 CFL1 CNTN1 CNTRL COPS6 CSE1L CYRIB CYTH2 DBN1 DCTN2 DDOST DDR1 DGKZ DKC1 DNAJC28 DPPA4 DST DYNC2I2 EDF1 EEF1A2 EIF1 EIF3C EIF4A1 ELOF1 EMD FBXL16 FOXO3 FXYD3 GALNT7 GATA1 GLRX3 GORASP1 GPX1 HACL1 HAUS2 HDAC11 HIP1 HNRNPA0 HNRNPD HNRNPH3 HSP90AB1 HSP90B1 HSPD1 IDH3B INS ITGB3BP ITSN1 JUNB KDSR KLC1 KNSTRN LPXN MAP3K12 MAP3K7 MAPKAPK5 MASP1 MBIP MBOAT7 MCM3 MDK METTL17 METTL2A MGAT1 MIPEP MOK MON1A MTG2 MYBL2 MYOZ3 MZB1 NAT9 NAXE NDUFS6 NECTIN2 NELFB NOL4 NRXN2 NUDT5 OSTF1 PDCD6IP PDLIM1 PHACTR3 PHC2 PHGDH PIH1D1 PLEKHM1 PLSCR1 PPBP PPP1R7 PPP2R1A PRKAB1 PRKAR1A PRKCB PRPF38A PSAT1 PSIP1 PTPMT1 RAB2A RAB31 RACK1 RANBP9 RAP1GAP RARA RBL1 RGS19 RPL10 RRP7A SEPTIN3 SEPTIN5 SERPINA4 SHC1 SLC20A1 SLC41A3 SMAD6 SMS SNAPC4 SNW1 SOCS3 SPG7 SPRR2D SPTAN1 SRSF5 STX7 TDP2 THAP4 TPI1 TTK TUBA1A UBA52 UBE2L3 URB1 USP20 VPS26C WDR26 WFS1 WWC1 XPO1 ZNF133 ZNF205 ZNF331 ZNF579 ZNF600 ZNF671 ZNF775	3 interacting genes: GOLPH3 GOLPH3L MAPK6
Entrez ID		5597	51809
HPRD ID		04213	10386
Ensembl ID		ENSG00000069956	ENSG00000109586
Uniprot IDs		Q16659	H0YAH3 Q86SF2
PDB IDs		6YKY 6YLC 6YLL 7AQB	6IWQ 6IWR
Enriched GO Terms of Interacting Partners?		Cytosol Cytoplasm Nucleus Protein Binding Extracellular Exosome Ubiquitin Protein Ligase Binding	Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Golgi Cisterna Phosphatidylinositol-4-phosphate Binding Golgi To Plasma Membrane Protein Transport Vesicle Budding From Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Golgi Cisterna Membrane Post-Golgi Vesicle-mediated Transport Golgi Organization Vesicle-mediated Transport To The Plasma Membrane Positive Regulation Of Protein Secretion Septin Cytoskeleton Protein Localization To Plasma Membrane Trans-Golgi Network Asymmetric Golgi Ribbon Formation Protein Targeting Establishment Of Protein Localization To Membrane Protein Localization To Cell Periphery Cell Adhesion Molecule Production Cellular Response To Rapamycin Positive Regulation Of Protein Transport Regulation Of Protein Secretion Protein Retention In Golgi Apparatus Golgi Vesicle Transport Positive Regulation Of Secretion By Cell Vesicle Organization Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Protein Localization To Membrane Response To Rapamycin Lipid Binding Establishment Of Protein Localization To Organelle Golgi Ribbon Formation Regulation Of Protein Transport Positive Regulation Of Protein Localization Cellular Response To Ether MAP Kinase Activity Localization Within Membrane Regulation Of Establishment Of Protein Localization Regulation Of Secretion By Cell Leukocyte Tethering Or Rolling Regulation Of Secretion Response To Ether Golgi Membrane Leukocyte Adhesion To Vascular Endothelial Cell Membrane Organization
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