PRMT7

Description		protein arginine methyltransferase 7
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Protein-arginine N-methyltransferase Activity Transferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Histone Methyltransferase Activity Histone Binding Ribonucleoprotein Complex Binding Histone H4R3 Methyltransferase Activity Histone H4 Methyltransferase Activity
	Biological Process	Spliceosomal SnRNP Assembly Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Peptidyl-arginine Methylation Cell Differentiation Methylation Genomic Imprinting
Pathways		RMTs methylate histone arginines
Drugs
Diseases
GWAS		A body shape index ( 34021172) Birth weight ( 31043758) Body mass index ( 25673413 28892062) Lipoprotein (a) levels ( 33730874) Magnesium levels ( 20700443) Offspring birth weight ( 31043758) Refractive error ( 32231278) Schizophrenia ( 31579629) Serum metabolite levels ( 23093944) Weight ( 28552196)
Novel Interacting Genes		1 novel interacting genes: TRIO
Interacting Genes		14 interacting genes: CTCFL DIO3 EIF2S1 H2AC20 H3-5 H3C1 H4C1 MNDA NFKBID POT1 SNRPB UBC ZBTB24 ZNF438
Entrez ID		54496
HPRD ID		15174
Ensembl ID		ENSG00000132600
Uniprot IDs		A0A8I5KPP4 A0A8I5KXS9 A0A8I5KYD6 A0A8I5KZ05 A0A8I5KZ92 H3BNC0 Q9NVM4
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Chromatin Nucleosome DNA Binding Chromosome Nucleus Protein Heterodimerization Activity Telomere Organization Translation Initiation Ternary Complex Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Retinal Cone Cell Apoptotic Process Thyroxine 5'-deiodinase Activity Thyroxine 5-deiodinase Activity Thyroid Hormone Catabolic Process Brown Fat Cell Proliferation Response To Manganese-induced Endoplasmic Reticulum Stress Glial Limiting End-foot Nucleoplasm SnRNP Binding U2 SnRNP Binding Chromatin Remodeling Epigenetic Regulation Of Gene Expression Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding
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