PRMT7 and DIO3

Number of citations of the paper that reports this interaction (PMID 17709427)
33

Data Source:
BioGRID (pull down)

		PRMT7	DIO3
Gene Name		protein arginine methyltransferase 7	deiodinase, iodothyronine, type III
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane	Plasma Membrane Endosome Membrane Integral Component Of Membrane
	Molecular Function	Histone-arginine N-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity [myelin Basic Protein]-arginine N-methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Histone Binding Ribonucleoprotein Complex Binding Histone Methyltransferase Activity (H4-R3 Specific)	Thyroxine 5'-deiodinase Activity Thyroxine 5-deiodinase Activity
	Biological Process	Spliceosomal SnRNP Assembly Chromatin Organization Regulation Of Gene Expression By Genetic Imprinting Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Cell Differentiation Histone Arginine Methylation DNA Methylation Involved In Gamete Generation Regulation Of Protein Binding Histone H4-R3 Methylation	Thyroid Hormone Generation Biological_process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Multicellular Organism Growth Thyroid Hormone Catabolic Process Hormone Biosynthetic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines	Amine-derived hormones Regulation of thyroid hormone activity Thyroxine biosynthesis Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS		Magnesium levels ( 20700443)	Type 1 diabetes ( 19966805)
Protein-Protein Interactions		10 interactors: CTCFL DIO3 H3F3C HIST1H3A HIST1H4A HIST2H2AC MNDA POT1 SNRPB ZBTB24	3 interactors: APP PRMT5 PRMT7
Entrez ID		54496	1735
HPRD ID		15174	11867
Ensembl ID		ENSG00000132600	ENSG00000197406
Uniprot IDs		Q9NVM4	P55073 Q86TU3
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Methylation DNA Modification DNA Replication-dependent Nucleosome Assembly DNA Methylation On Cytosine Chromatin Silencing At RDNA Regulation Of Gene Expression, Epigenetic Cellular Aromatic Compound Metabolic Process Chromatin Silencing Cellular Nitrogen Compound Metabolic Process DNA Conformation Change Nitrogen Compound Metabolic Process Telomere Maintenance Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of DNA Strand Elongation Chromosome Organization Methylation DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Silencing Thyroid Hormone Catabolic Process Heterocycle Metabolic Process Nucleosome Assembly Gene Expression Telomere Formation Via Telomerase Histone H4-K20 Demethylation Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Cellular Macromolecular Complex Assembly Negative Regulation Of Megakaryocyte Differentiation Protein-DNA Complex Assembly Positive Regulation Of Helicase Activity Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase DNA Packaging Chromatin Organization Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Hormone Catabolic Process Regulation Of Chromosome Organization Positive Regulation Of Growth Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Cellular Component Assembly Regulation Of Telomerase Activity	Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Histone H4-R3 Methylation Peptidyl-arginine N-methylation Histone Arginine Methylation Peptidyl-arginine Methylation MRNA Processing Spliceosomal SnRNP Assembly MRNA Metabolic Process RNA Processing Histone Methylation Regulation Of Protein Binding Protein Methylation Ribonucleoprotein Complex Assembly Synaptic Growth At Neuromuscular Junction MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Collateral Sprouting In Absence Of Injury Regulation Of Binding Cellular Component Assembly Ribonucleoprotein Complex Biogenesis Collateral Sprouting Axon Midline Choice Point Recognition RNA Splicing Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Histone Modification Axon Choice Point Recognition Methylation Regulation Of Mitotic Cell Cycle Neuron Remodeling Regulation Of Cell Cycle Process Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Endothelial Cell Activation Chromatin Modification Cellular Macromolecular Complex Assembly Cellular Copper Ion Homeostasis DNA Methylation Involved In Gamete Generation Cell Activation RNA Metabolic Process Cellular Protein Modification Process Chromatin Organization Copper Ion Homeostasis Suckling Behavior Regulation Of Gene Expression By Genetic Imprinting Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Gene Expression Sexual Reproduction Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Genetic Imprinting
Tagcloud ?			capsule deleting distal dlk1 dysregulation e6 embryos encoded encodes engrafting gtl2 harbors hypertrophic maternally microarray mirnas ncrnas noncoding paternally reflects repression rnas scid suppressors teratoma teratomas tumorigenesis wildtype works
Tagcloud (Difference) ?			capsule deleting distal dlk1 dysregulation e6 embryos encoded encodes engrafting gtl2 harbors hypertrophic maternally microarray mirnas ncrnas noncoding paternally reflects repression rnas scid suppressors teratoma teratomas tumorigenesis wildtype works
Tagcloud (Intersection) ?