PRMT7 and MNDA

Number of citations of the paper that reports this interaction (PubMedID 23455924)
0

Data Source:
BioGRID (two hybrid)

		PRMT7	MNDA
Description		protein arginine methyltransferase 7	myeloid cell nuclear differentiation antigen
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Azurophil Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Protein-arginine N-methyltransferase Activity Transferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Histone Methyltransferase Activity Histone Binding Ribonucleoprotein Complex Binding Histone H4R3 Methyltransferase Activity Histone H4 Methyltransferase Activity	DNA Binding Double-stranded DNA Binding Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Peptidyl-arginine Methylation Cell Differentiation Methylation Genomic Imprinting	Activation Of Innate Immune Response Cellular Defense Response DNA Damage Response Negative Regulation Of B Cell Proliferation Cellular Response To Interferon-beta Positive Regulation Of Apoptotic Process B Cell Receptor Signaling Pathway
Pathways		RMTs methylate histone arginines	Neutrophil degranulation
Drugs
Diseases
GWAS		A body shape index ( 34021172) Birth weight ( 31043758) Body mass index ( 25673413 28892062) Lipoprotein (a) levels ( 33730874) Magnesium levels ( 20700443) Offspring birth weight ( 31043758) Refractive error ( 32231278) Schizophrenia ( 31579629) Serum metabolite levels ( 23093944) Weight ( 28552196)	Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Perceived intensity of aspartame ( 31005972)
Interacting Genes		14 interacting genes: CTCFL DIO3 EIF2S1 H2AC20 H3-5 H3C1 H4C1 MNDA NFKBID POT1 SNRPB UBC ZBTB24 ZNF438	14 interacting genes: CDK1 CDK2 CEBPA CRK FBXO7 HOXB2 MAPK8IP2 NSD3 PRMT6 PRMT7 RB1 RBL2 STAT3 TP53
Entrez ID		54496	4332
HPRD ID		15174	15932
Ensembl ID		ENSG00000132600	ENSG00000163563
Uniprot IDs		A0A8I5KPP4 A0A8I5KXS9 A0A8I5KYD6 A0A8I5KZ05 A0A8I5KZ92 H3BNC0 Q9NVM4	P41218 Q5VUU6
PDB IDs			2DBG 5H7Q 5WPZ 8I6K
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Chromatin Nucleosome DNA Binding Chromosome Nucleus Protein Heterodimerization Activity Telomere Organization Translation Initiation Ternary Complex Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Retinal Cone Cell Apoptotic Process Thyroxine 5'-deiodinase Activity Thyroxine 5-deiodinase Activity Thyroid Hormone Catabolic Process Brown Fat Cell Proliferation Response To Manganese-induced Endoplasmic Reticulum Stress Glial Limiting End-foot Nucleoplasm SnRNP Binding U2 SnRNP Binding Chromatin Remodeling Epigenetic Regulation Of Gene Expression Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding	Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Transcription Regulator Complex Negative Regulation Of Cell Cycle Process Chromatin Organization Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cell Cycle G1/S Phase Transition Chromatin Remodeling Regulation Of Cell Cycle Regulation Of RNA Metabolic Process Regulation Of Cell Cycle Phase Transition Cyclin-dependent Protein Kinase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Mitotic Cell Cycle Intracellular Signaling Cassette Histone Methyltransferase Activity Regulation Of Lipid Kinase Activity Nucleoplasm Regulation Of Transcription By RNA Polymerase II Rb-E2F Complex Glial Cell Apoptotic Process Histone H4R3 Methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Nucleus Histone Kinase Activity Chromatin Cell Population Proliferation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of MiRNA Processing Regulation Of Cell Cycle Process Cellular Senescence DNA-templated Transcription Cellular Response To Xenobiotic Stimulus Regulation Of Hemopoiesis Protein-arginine N-methyltransferase Activity Mitotic DNA Damage Checkpoint Signaling Protein-containing Complex Mitotic DNA Integrity Checkpoint Signaling Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Ras Protein Signal Transduction Regulation Of Cell Development G1/S Transition Of Mitotic Cell Cycle
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