ALAS1 and TEKT4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ALAS1	TEKT4
Gene Name		5-aminolevulinate synthase 1	tektin 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix	Nucleus Cytoplasm Microtubule Motile Cilium
	Molecular Function	5-aminolevulinate Synthase Activity Pyridoxal Phosphate Binding
	Biological Process	Porphyrin-containing Compound Metabolic Process Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process Organelle Organization Mitochondrion Organization Cellular Lipid Metabolic Process Small Molecule Metabolic Process	Cell Projection Organization
Pathways		PPARA activates gene expression Heme biosynthesis Organelle biogenesis and maintenance Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Metabolism of porphyrins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs		Pyridoxal Phosphate Glycine
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		40 interactors: BCL7A C2orf42 C8orf33 CCHCR1 CDC73 CDK5 CDKN1A CERK DUSP19 EP400 FAM127C GNL3L KLHL35 LONRF1 MTFR2 NUDT3 PIK3CB PLAU POLDIP2 PPL RAP1B SH2D4A SNX20 STAMBP SUMO2 TCEA2 TEKT4 TK1 TMSB10 TMSB4X TMSB4XP1 TMSB4XP2 TMSB4XP6 TTC23 USP20 WIPF1 ZFYVE26 ZMAT1 ZNF175 ZNF564	15 interactors: ALAS1 ATG5 GSE1 HNRNPM IKZF3 KRT15 KRTAP26-1 MAGEA4 PRDM14 RARA RECK SLC25A6 SMAD3 TADA2A TRIP6
Entrez ID		211	150483
HPRD ID		00505	14518
Ensembl ID		ENSG00000023330	ENSG00000163060
Uniprot IDs		P13196 Q5JAM2	E7EVC1 Q8WW24
PDB IDs
Enriched GO Terms of Interacting Partners?		Sequestering Of Actin Monomers Blood Coagulation Hemostasis Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity	Modulation By Virus Of Host Morphology Or Physiology RNA Metabolic Process RNA Biosynthetic Process Ventricular Cardiac Muscle Cell Differentiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription Factor Import Into Nucleus Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Regulation Of Immune System Process Response To Other Organism Nitrogen Compound Metabolic Process Response To Biotic Stimulus Histone H3-R26 Methylation Positive Regulation Of Transforming Growth Factor Beta3 Production Sertoli Cell Fate Commitment Inner Cell Mass Cell Fate Commitment Regulation Of Protein Localization Negative Regulation Of Cellular Protein Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Regulation Of Immune Response Cardiovascular System Development Regulation Of Cartilage Development Gene Expression Negative Regulation Of Protein Metabolic Process Regulation Of Transcription Factor Import Into Nucleus Active Induction Of Host Immune Response By Virus Mitochondrion Organization Positive Regulation Of Protein Import Into Nucleus Cellular Macromolecule Biosynthetic Process Biosynthetic Process Interaction With Host Macromolecule Biosynthetic Process Tissue Development Regulation Of Intracellular Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport ADP Transport Evasion Or Tolerance Of Host Defenses By Virus Cardiac Muscle Cell Differentiation Posttranscriptional Regulation Of Gene Expression Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Regulation Of Cellular Localization Mesonephros Development Regulation Of Histone Modification
Tagcloud ?		adequate arf1 candidate eif2b1 fbxw2 genorm gusb housekeeping hprt1 hysterectomy ideal leiomyoma menopausal menstrual mrpl19 myometrial myometrium normalization normfinder phases proliferative pum1 regardless secretory softwares standards taqman trim27 ube2d2
Tagcloud (Difference) ?		adequate arf1 candidate eif2b1 fbxw2 genorm gusb housekeeping hprt1 hysterectomy ideal leiomyoma menopausal menstrual mrpl19 myometrial myometrium normalization normfinder phases proliferative pum1 regardless secretory softwares standards taqman trim27 ube2d2
Tagcloud (Intersection) ?