ALAS1 and BCL7A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ALAS1	BCL7A
Gene Name		5-aminolevulinate synthase 1	B-cell CLL/lymphoma 7A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix	Cellular_component
	Molecular Function	5-aminolevulinate Synthase Activity Pyridoxal Phosphate Binding	Molecular_function
	Biological Process	Porphyrin-containing Compound Metabolic Process Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process Organelle Organization Mitochondrion Organization Cellular Lipid Metabolic Process Small Molecule Metabolic Process	Negative Regulation Of Transcription, DNA-templated
Pathways		PPARA activates gene expression Heme biosynthesis Organelle biogenesis and maintenance Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Metabolism of porphyrins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs		Pyridoxal Phosphate Glycine
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		40 interactors: BCL7A C2orf42 C8orf33 CCHCR1 CDC73 CDK5 CDKN1A CERK DUSP19 EP400 FAM127C GNL3L KLHL35 LONRF1 MTFR2 NUDT3 PIK3CB PLAU POLDIP2 PPL RAP1B SH2D4A SNX20 STAMBP SUMO2 TCEA2 TEKT4 TK1 TMSB10 TMSB4X TMSB4XP1 TMSB4XP2 TMSB4XP6 TTC23 USP20 WIPF1 ZFYVE26 ZMAT1 ZNF175 ZNF564	2 interactors: ALAS1 RELB
Entrez ID		211	605
HPRD ID		00505	03243
Ensembl ID		ENSG00000023330
Uniprot IDs		P13196 Q5JAM2	Q4VC05
PDB IDs
Enriched GO Terms of Interacting Partners?		Sequestering Of Actin Monomers Blood Coagulation Hemostasis Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity	Protoporphyrinogen IX Biosynthetic Process Protoporphyrinogen IX Metabolic Process T-helper 1 Cell Differentiation Myeloid Dendritic Cell Differentiation Myeloid Dendritic Cell Activation T-helper 1 Type Immune Response Heme Biosynthetic Process T-helper Cell Differentiation Cellular Response To Osmotic Stress Porphyrin-containing Compound Biosynthetic Process Dendritic Cell Differentiation CD4-positive, Alpha-beta T Cell Differentiation NIK/NF-kappaB Signaling Heme Metabolic Process CD4-positive, Alpha-beta T Cell Activation Porphyrin-containing Compound Metabolic Process I-kappaB Kinase/NF-kappaB Signaling Pigment Biosynthetic Process Alpha-beta T Cell Differentiation Alpha-beta T Cell Activation T Cell Activation Involved In Immune Response Circadian Regulation Of Gene Expression Tetrapyrrole Metabolic Process Response To Osmotic Stress Myeloid Leukocyte Differentiation
Tagcloud ?		adequate arf1 candidate eif2b1 fbxw2 genorm gusb housekeeping hprt1 hysterectomy ideal leiomyoma menopausal menstrual mrpl19 myometrial myometrium normalization normfinder phases proliferative pum1 regardless secretory softwares standards taqman trim27 ube2d2	baf bcl11a bcl11b bcl7b bcl7c brd9 broad complexes constitute crc dedicated exhibiting exome functioning heterozygosity incorporating mswi mutated notably polymorphic prevalent proper protect proteomic snf ss18 subunits suppressors swi
Tagcloud (Difference) ?		adequate arf1 candidate eif2b1 fbxw2 genorm gusb housekeeping hprt1 hysterectomy ideal leiomyoma menopausal menstrual mrpl19 myometrial myometrium normalization normfinder phases proliferative pum1 regardless secretory softwares standards taqman trim27 ube2d2	baf bcl11a bcl11b bcl7b bcl7c brd9 broad complexes constitute crc dedicated exhibiting exome functioning heterozygosity incorporating mswi mutated notably polymorphic prevalent proper protect proteomic snf ss18 subunits suppressors swi
Tagcloud (Intersection) ?