ALAS1 and ZMAT1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		ALAS1	ZMAT1
Description		5'-aminolevulinate synthase 1	zinc finger matrin-type 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytosol Membrane	Nucleus
	Molecular Function	5-aminolevulinate Synthase Activity Protein Binding Transferase Activity Acyltransferase Activity Pyridoxal Phosphate Binding Identical Protein Binding	Nucleic Acid Binding DNA Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Response To Hypoxia Porphyrin-containing Compound Metabolic Process Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process Heme A Biosynthetic Process Heme B Biosynthetic Process Response To Xenobiotic Stimulus Response To Herbicide Response To Nickel Cation Response To Nutrient Levels Response To Cobalt Ion Cellular Response To Insulin Stimulus Tetrapyrrole Biosynthetic Process Response To Gonadotropin Hemoglobin Biosynthetic Process Response To Ethanol Heme O Biosynthetic Process Erythrocyte Development Response To CAMP Response To Platinum Ion Response To Bile Acid
Pathways		Heme biosynthesis PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Mitochondrial protein degradation
Drugs		Pyridoxal phosphate Pyridoxal phosphate Glycine
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Parkinson's disease ( 28892059) Schizophrenia ( 23974872)
Interacting Genes		54 interacting genes: BCL7A C2orf42 C8orf33 CAP2 CCHCR1 CDC73 CDK5 CDKN1A CERK COBL EP400 FBXL8 FXR1 GNL3L GRXCR1 HSBP1L1 JRK KIF9 KLHL35 LONRF1 LRRC45 MTFR2 MTSS2 NUDT3 OXTR PIBF1 PIK3CB PLAU POLDIP2 PPL RAP1B RNF168 RTL8B SH2D4A SNRPB2 SNX20 STAMBP SUMO2 TCEA2 TEKT4 TK1 TMSB10 TMSB4X TMSB4XP1 TMSB4XP2 TMSB4XP6 TTC23 USP20 UTP14C WIPF1 ZFYVE26 ZMAT1 ZNF175 ZNF564	23 interacting genes: ABL2 AIRIM ALAS1 BLK BLZF1 CDC23 DUSP21 EXOSC5 GOLGA2 GORASP2 GRB2 HOXA1 LZTS2 MYO15B OIP5 PIK3R3 QRICH1 RFC5 RUNX1T1 SAXO1 SCNM1 STK16 ZNF124
Entrez ID		211	84460
HPRD ID		00505	10029
Ensembl ID		ENSG00000023330	ENSG00000166432
Uniprot IDs		B4DVA0 P13196 Q5JAM2	A7MD47 Q5H9K5
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin Monomer Binding	Phosphotyrosine Residue Binding Non-membrane Spanning Protein Tyrosine Kinase Activity Cis-Golgi Network
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?