TEKT4 and TFAP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TEKT4	TFAP4
Description		tektin 4	transcription factor AP-4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Axonemal Microtubule Cilium Microtubule Cytoskeleton Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath	Chromatin Nucleus Nucleoplasm Mitochondrion Transcription Repressor Complex
	Molecular Function	Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Sequence-specific DNA Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cell Projection Organization Flagellated Sperm Motility Cilium Assembly Cilium Movement Involved In Cell Motility	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Apoptotic Process Negative Regulation Of DNA Binding Host-mediated Suppression Of Viral Transcription Host-mediated Activation Of Viral Transcription Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly Cellular Response To Dexamethasone Stimulus Regulation Of Mitotic Cell Cycle Phase Transition
Pathways
Drugs
Diseases
GWAS		Parkinson's disease ( 34064523)	Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Lung function (FEV1/FVC) ( 26635082) Platelet count ( 32888494) Prostate-specific antigen levels ( 28139693) Serum alkaline phosphatase levels ( 33547301) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		105 interacting genes: ACBD4 AIRIM AKAP8L ALAS1 AMMECR1 ANKRD55 ARID5A ATG5 BCL6 BLZF1 BORCS8-MEF2B CFAP68 CTDSP1 DDIT4L EFHC2 EYA2 FAM220A GATA1 GPSM1 GRB10 GSE1 HCK HDAC6 HNRNPH1 HNRNPM HOXA1 HOXB5 HOXC8 IKZF3 INCA1 KPRP KRT15 KRT18 KRT34 KRT35 KRT75 KRT86 KRTAP11-1 KRTAP13-1 KRTAP13-3 KRTAP19-1 KRTAP19-2 KRTAP19-6 KRTAP26-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 LASP1 LMCD1 LNX1 MAGEA4 MIIP MORN3 MYOZ3 NANOS3 NFKBID NR5A1 PCSK5 PHF11 PKP2 PLAGL2 POLDIP3 PPP1R13B PRDM14 PRDM6 PROP1 PSMA1 PTH1R RAMAC RARA RBM48 RECK RFX6 RUSC1 SAXO4 SCN5A SLC25A6 SMAD3 SOCS4 SPATA8 SPATC1L SPG21 SPMIP6 SUV39H1 TADA2A TEKT1 TFAP4 TOX2 TRIB3 TRIP6 TSPAN4 UBASH3A USP2 VGLL1 ZFP90 ZIM2 ZMYND12 ZNF20 ZNF417 ZNF426 ZNF474 ZNF552 ZNF581 ZNF655 ZNF688	12 interacting genes: AJUBA EXOSC8 GOLGA2 INCA1 MCRS1 PDE9A PTPN3 SFMBT2 TEKT4 TRAF1 TRAF4 VMAC
Entrez ID		150483	7023
HPRD ID		14518	11795
Ensembl ID		ENSG00000163060	ENSG00000090447
Uniprot IDs		A0A384MEB7 Q8WW24	Q01664
PDB IDs		7UNG
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Keratin Filament Nucleus Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Axonemal A Tubule Inner Sheath Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Intermediate Filament Organization Zinc Ion Binding Regulation Of RNA Metabolic Process DNA Binding DNA-binding Transcription Factor Activity Chromatin DNA Binding Structural Molecule Activity Histone Deacetylase Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Structural Constituent Of Skin Epidermis Regulation Of Nucleobase-containing Compound Metabolic Process Flagellated Sperm Motility Sperm Motility DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cilium-dependent Cell Motility Sperm Flagellum Regulation Of Primary Metabolic Process Cilium Movement Involved In Cell Motility Nucleoplasm Sequence-specific Double-stranded DNA Binding Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Sequence-specific DNA Binding Cilium Movement Negative Regulation Of RNA Metabolic Process Keratinization Erythrocyte Development	Thioesterase Binding Cytoskeleton Tumor Necrosis Factor Receptor Binding
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