TEKT4 and IKZF3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TEKT4	IKZF3
Gene Name		tektin 4	IKAROS family zinc finger 3 (Aiolos)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Motile Cilium	Nucleus Cytoplasm Plasma Membrane
	Molecular Function		Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Cell Projection Organization	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Mesoderm Development Regulation Of B Cell Proliferation B Cell Activation Regulation Of Apoptotic Process Regulation Of B Cell Differentiation Regulation Of Lymphocyte Differentiation
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Primary biliary cirrhosis ( 19458352 23000144 20639880) Rheumatoid arthritis ( 20453842) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		15 interactors: ALAS1 ATG5 GSE1 HNRNPM IKZF3 KRT15 KRTAP26-1 MAGEA4 PRDM14 RARA RECK SLC25A6 SMAD3 TADA2A TRIP6	71 interactors: ABLIM3 AES AKAP9 AQP1 ARMC7 ARNT2 ATPAF2 BCAS2 BCL2L1 C1orf109 CABP5 CDKN1A CDKN2D CHCHD2 CHD3 DGCR6 EFHC1 EMC2 EXOC8 EXOSC5 FANCL FARS2 FBF1 GEM GRB2 HNRNPF HRAS IKZF1 IKZF4 IKZF5 ING5 KAT5 KRT19 LGALS14 LMO1 LMO2 MAGOHB MORN3 MRPL28 MRPL53 NATD1 NEK6 OAZ3 OSGIN1 PCID2 PFDN5 PIK3R2 PIN1 POLM POLR1C PPP1R16B PRKAA1 PRKAB2 PSMA1 RAD51D RBBP8 RCOR3 RHOA SPG21 STAMBPL1 STK16 STX11 TBC1D22B TCAF1 TEKT4 TRAPPC6A TRIM42 TSSK3 TSTD2 UBE2I ZGPAT
Entrez ID		150483	22806
HPRD ID		14518	05869
Ensembl ID		ENSG00000163060
Uniprot IDs		E7EVC1 Q8WW24	Q9UKT9
PDB IDs
Enriched GO Terms of Interacting Partners?		Modulation By Virus Of Host Morphology Or Physiology RNA Metabolic Process RNA Biosynthetic Process Ventricular Cardiac Muscle Cell Differentiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription Factor Import Into Nucleus Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Regulation Of Immune System Process Response To Other Organism Nitrogen Compound Metabolic Process Response To Biotic Stimulus Histone H3-R26 Methylation Positive Regulation Of Transforming Growth Factor Beta3 Production Sertoli Cell Fate Commitment Inner Cell Mass Cell Fate Commitment Regulation Of Protein Localization Negative Regulation Of Cellular Protein Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Regulation Of Immune Response Cardiovascular System Development Regulation Of Cartilage Development Gene Expression Negative Regulation Of Protein Metabolic Process Regulation Of Transcription Factor Import Into Nucleus Active Induction Of Host Immune Response By Virus Mitochondrion Organization Positive Regulation Of Protein Import Into Nucleus Cellular Macromolecule Biosynthetic Process Biosynthetic Process Interaction With Host Macromolecule Biosynthetic Process Tissue Development Regulation Of Intracellular Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport ADP Transport Evasion Or Tolerance Of Host Defenses By Virus Cardiac Muscle Cell Differentiation Posttranscriptional Regulation Of Gene Expression Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Regulation Of Cellular Localization Mesonephros Development Regulation Of Histone Modification	Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Organelle Organization Gene Expression Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Radiation Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Cellular Response To Organonitrogen Compound Response To Hormone Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint RNA Metabolic Process Response To Ionizing Radiation Cell Cycle Arrest Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Immune System Process Response To Stress Nitrogen Compound Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Signaling Ammonium Transmembrane Transport Biosynthetic Process Macromolecule Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cellular Response To Organic Substance Response To Organonitrogen Compound
Tagcloud ?			17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Difference) ?			17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Intersection) ?