TEKT4 and FAM220A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TEKT4	FAM220A
Description		tektin 4	family with sequence similarity 220 member A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Axonemal Microtubule Cilium Microtubule Cytoskeleton Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath	Acrosomal Vesicle Nucleus Cytoplasm Cytoplasmic Vesicle
	Molecular Function	Protein Binding	Protein Binding STAT Family Protein Binding
	Biological Process	Cell Projection Organization Flagellated Sperm Motility Cilium Assembly Cilium Movement Involved In Cell Motility	Negative Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Parkinson's disease ( 34064523)	Body mass index ( 26426971) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		105 interacting genes: ACBD4 AIRIM AKAP8L ALAS1 AMMECR1 ANKRD55 ARID5A ATG5 BCL6 BLZF1 BORCS8-MEF2B CFAP68 CTDSP1 DDIT4L EFHC2 EYA2 FAM220A GATA1 GPSM1 GRB10 GSE1 HCK HDAC6 HNRNPH1 HNRNPM HOXA1 HOXB5 HOXC8 IKZF3 INCA1 KPRP KRT15 KRT18 KRT34 KRT35 KRT75 KRT86 KRTAP11-1 KRTAP13-1 KRTAP13-3 KRTAP19-1 KRTAP19-2 KRTAP19-6 KRTAP26-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 LASP1 LMCD1 LNX1 MAGEA4 MIIP MORN3 MYOZ3 NANOS3 NFKBID NR5A1 PCSK5 PHF11 PKP2 PLAGL2 POLDIP3 PPP1R13B PRDM14 PRDM6 PROP1 PSMA1 PTH1R RAMAC RARA RBM48 RECK RFX6 RUSC1 SAXO4 SCN5A SLC25A6 SMAD3 SOCS4 SPATA8 SPATC1L SPG21 SPMIP6 SUV39H1 TADA2A TEKT1 TFAP4 TOX2 TRIB3 TRIP6 TSPAN4 UBASH3A USP2 VGLL1 ZFP90 ZIM2 ZMYND12 ZNF20 ZNF417 ZNF426 ZNF474 ZNF552 ZNF581 ZNF655 ZNF688	3 interacting genes: NEK6 PTPN2 TEKT4
Entrez ID		150483	84792
HPRD ID		14518	14427
Ensembl ID		ENSG00000163060	ENSG00000178397
Uniprot IDs		A0A384MEB7 Q8WW24	Q7Z4H9
PDB IDs		7UNG
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Keratin Filament Nucleus Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Axonemal A Tubule Inner Sheath Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Intermediate Filament Organization Zinc Ion Binding Regulation Of RNA Metabolic Process DNA Binding DNA-binding Transcription Factor Activity Chromatin DNA Binding Structural Molecule Activity Histone Deacetylase Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Structural Constituent Of Skin Epidermis Regulation Of Nucleobase-containing Compound Metabolic Process Flagellated Sperm Motility Sperm Motility DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cilium-dependent Cell Motility Sperm Flagellum Regulation Of Primary Metabolic Process Cilium Movement Involved In Cell Motility Nucleoplasm Sequence-specific Double-stranded DNA Binding Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Sequence-specific DNA Binding Cilium Movement Negative Regulation Of RNA Metabolic Process Keratinization Erythrocyte Development	Negative Regulation Of Interleukin-4-mediated Signaling Pathway Positive Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Positive Thymic T Cell Selection Negative Regulation Of Positive Thymic T Cell Selection Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Interleukin-2-mediated Signaling Pathway Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Negative Regulation Of Macrophage Colony-stimulating Factor Signaling Pathway Insulin Receptor Recycling Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Type II Interferon-mediated Signaling Pathway Negative Regulation Of Macrophage Differentiation Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Non-membrane Spanning Protein Tyrosine Phosphatase Activity Negative Regulation Of T Cell Differentiation In Thymus Protein Kinase Binding Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Type II Interferon-mediated Signaling Pathway Regulation Of Response To Type II Interferon STAT Family Protein Binding Mitotic Nuclear Membrane Disassembly Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Nuclear Membrane Disassembly Regulation Of PERK-mediated Unfolded Protein Response Membrane Disassembly Negative Regulation Of Peptidyl-tyrosine Phosphorylation Endosome Lumen Negative Regulation Of Lipid Storage Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of T Cell Differentiation In Thymus Regulation Of Macrophage Differentiation Positive Regulation Of Gluconeogenesis Axonemal A Tubule Inner Sheath Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Receptor Recycling Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Receptor Signaling Pathway Via STAT Organelle Assembly Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Axonemal Microtubule Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Unfolded Protein Response Microtubule-based Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?