ITGB4 and CLCA2

Number of citations of the paper that reports this interaction (PMID 12110680)
21

Data Source:
HPRD (in vitro, in vivo)

		ITGB4	CLCA2
Gene Name		integrin, beta 4	chloride channel accessory 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Basement Membrane Plasma Membrane Integrin Complex Basal Plasma Membrane Cell Surface Hemidesmosome Cell Leading Edge Receptor Complex Extracellular Vesicular Exosome	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Cell Junction
	Molecular Function	G-protein Coupled Receptor Binding Receptor Activity Protein Binding	Chloride Channel Activity Metallopeptidase Activity Ligand-gated Ion Channel Activity Metal Ion Binding
	Biological Process	Autophagy Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Response To Wounding Extracellular Matrix Organization Hemidesmosome Assembly Cell Junction Assembly Nail Development Skin Development Filopodium Assembly Mesodermal Cell Differentiation Digestive Tract Development Cell Motility Renal System Development Amelogenesis	Proteolysis Transport Cell Adhesion Ion Transmembrane Transport Transmembrane Transport Chloride Transmembrane Transport
Pathways		Cell junction organization Syndecan interactions Type I hemidesmosome assembly Collagen formation Laminin interactions Non-integrin membrane-ECM interactions Assembly of collagen fibrils and other multimeric structures	Ion channel transport Stimuli-sensing channels Orphan transporters
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: ALOX12 ATXN1 CLCA1 CLCA2 COL17A1 DST EIF6 ERBB2 ERBB2IP FYN GRB2 ITGA6 MET PLEC PRKCA PRKCD PTK2 SHC1 SREBF2 VIM YES1 YWHAB YWHAQ	1 interactors: ITGB4
Entrez ID		3691	9635
HPRD ID		00946	04923
Ensembl ID		ENSG00000132470	ENSG00000137975
Uniprot IDs		P16144	Q9UQC9
PDB IDs		1QG3 2YRZ 3F7P 3F7Q 3F7R 3FQ4 3FSO 3H6A
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell-cell Adhesion Fc Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Fibroblast Growth Factor Receptor Signaling Pathway Response To Wounding Cellular Response To Fibroblast Growth Factor Stimulus Hemidesmosome Assembly Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Regulation Of Body Fluid Levels Response To Growth Factor Wound Healing Regulation Of Cell Adhesion Peptidyl-tyrosine Phosphorylation Blood Coagulation Hemostasis Locomotion Immune Response-regulating Signaling Pathway Platelet Activation Protein Autophosphorylation Innate Immune Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Chemotaxis Axon Guidance Leukocyte Migration Cell Motility Positive Regulation Of Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Phosphorylation Apoptotic Process Cell-substrate Junction Assembly Regulation Of Cell Activation Programmed Cell Death Cell Death Death Cellular Response To Peptide Hormone Stimulus Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cellular Response To Organic Substance Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Platelet Aggregation Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway	Nail Development Hemidesmosome Assembly Amelogenesis Filopodium Assembly Mesodermal Cell Differentiation Cell-substrate Junction Assembly Mesoderm Formation Mesoderm Morphogenesis Odontogenesis Of Dentin-containing Tooth Integrin-mediated Signaling Pathway Formation Of Primary Germ Layer Odontogenesis Digestive Tract Development Mesoderm Development Digestive System Development Autophagy Cell-matrix Adhesion Gastrulation Cell Junction Assembly Limb Development Cell-substrate Adhesion Skin Development Cell Projection Assembly Renal System Development Extracellular Matrix Organization Extracellular Structure Organization Urogenital System Development
Tagcloud ?		bag1 bcl2l2 bctis ccna2 comprehend ctsb deregulations fgf1 fosl1 gabrp gsn hnepi id2 il6r klf5 klk5 map2k7 microdissected ngfb ngfr ontological pappa plau scgb1d2 scgb2a1 serpinb5 serpine1 thbs1 thbs2	01x10 27x10 2q24 2x10 3x10 94x10 ancestry bowel complicated comprising course crohn erythema european extra genotyped gwas gwass location loci ly75 magi1 manifestations nodosum pcombined phenotypes replicated structuring variants
Tagcloud (Difference) ?		bag1 bcl2l2 bctis ccna2 comprehend ctsb deregulations fgf1 fosl1 gabrp gsn hnepi id2 il6r klf5 klk5 map2k7 microdissected ngfb ngfr ontological pappa plau scgb1d2 scgb2a1 serpinb5 serpine1 thbs1 thbs2	01x10 27x10 2q24 2x10 3x10 94x10 ancestry bowel complicated comprising course crohn erythema european extra genotyped gwas gwass location loci ly75 magi1 manifestations nodosum pcombined phenotypes replicated structuring variants
Tagcloud (Intersection) ?