EFNB1 and ANKRD46

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EFNB1	ANKRD46
Description		ephrin B1	ankyrin repeat domain 46
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Cell Surface Membrane Presynaptic Membrane Membrane Raft Synapse Extracellular Exosome Glutamatergic Synapse	Membrane
	Molecular Function	Protein Binding Ephrin Receptor Binding	Protein Binding
	Biological Process	Neural Crest Cell Migration Cell Adhesion Cell-cell Signaling Nervous System Development Axon Guidance Embryonic Pattern Specification Cell Differentiation T Cell Costimulation T Cell Proliferation Positive Regulation Of T Cell Proliferation Ephrin Receptor Signaling Pathway Regulation Of Autophagosome Assembly
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs
Diseases		Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome
GWAS			Atrioventricular conduction ( 21041692) Body mass index ( 26426971) Percentage gas trapping ( 26030696)
Interacting Genes		17 interacting genes: ANKRD46 CAPN10 CUL3 EPHA3 EPHB1 EPHB2 GRIP1 MYC NCK2 PICK1 PTPN13 RGS3 SDCBP SORBS1 SRC TIAM1 YWHAQ	63 interacting genes: AMIGO1 APH1A AQP6 ARL13B BIK BSCL2 C16orf54 CD22 CD46 CLDN20 CLDN7 CLEC4D CRB3 CREB3L1 CXADR CYB561 EBP EFNB1 EFNB2 ELOVL4 FAM174A FAM209A FFAR2 GOLM1 GPR152 GPR42 GPX8 HSD17B11 HSD17B13 IFNLR1 KASH5 KIR2DL3 LAMTOR5 LDLRAD1 LRRC25 MFF MMGT1 MUC1 NCAPH2 NSG2 PLPP4 PVR RELL2 RETREG3 SCN3B SECTM1 SHISA3 SLC10A6 SLC16A2 SLC18A1 SLC39A9 ST6GALNAC6 STX1A STX2 STX4 SUSD3 THAP4 TIMMDC1 TMEM248 TMEM31 TMEM45B TMEM79 TMPRSS2
Entrez ID		1947	157567
HPRD ID		02072	14103
Ensembl ID		ENSG00000090776	ENSG00000186106
Uniprot IDs		P98172	B3KT99 Q86W74
PDB IDs		6THG
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Positive Regulation Of Cellular Component Organization Regulation Of Cellular Component Organization Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Transmembrane-ephrin Receptor Activity Ephrin Receptor Activity Dendritic Spine Development Regulation Of Organelle Organization Regulation Of Cell Communication Regulation Of Signaling Enzyme-linked Receptor Protein Signaling Pathway Contractile Actin Filament Bundle Assembly Stress Fiber Assembly Regulation Of Cell Junction Assembly Dendritic Spine Organization Signaling Receptor Complex Adaptor Activity Cell Recognition Protein Tyrosine Kinase Activity Optic Nerve Morphogenesis Hindbrain Tangential Cell Migration Neuron Projection Organization Postsynapse Organization Signal Transduction Cell Migration Cell-substrate Adhesion Protein Phosphorylation Peptidyl-tyrosine Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Activity Positive Regulation Of Cell Projection Organization Plasma Membrane Cytosol Regulation Of Signal Transduction Cellular Response To Peptide Hormone Stimulus Signal Complex Assembly Phosphorylation Actin Filament Bundle Assembly Cell Surface Receptor Signaling Pathway Cell Motility Positive Regulation Of Protein Localization To Plasma Membrane Actin Filament Bundle Organization Regulation Of Intracellular Signal Transduction Negative Regulation Of Cellular Component Organization Cell Projection Organization Membrane Raft Axon Guidance Receptor Activity Fibroblast Apoptotic Process Positive Regulation Of Protein Localization Positive Regulation Of Protein Localization To Cell Periphery Cell Migration In Hindbrain Positive Regulation Of Protein Localization To Membrane	Membrane Protein Binding Plasma Membrane Steroid Dehydrogenase Activity
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