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CDC23 and FAM9B
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CDC23
FAM9B
Gene Name
cell division cycle 23
family with sequence similarity 9, member B
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Nucleoplasm
Anaphase-promoting Complex
Cytosol
Nucleoplasm
Molecular Function
Ubiquitin-protein Transferase Activity
Biological Process
Mitotic Cell Cycle
Ubiquitin-dependent Protein Catabolic Process
Mitotic Nuclear Division
Mitotic Metaphase Plate Congression
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Mitotic Spindle Assembly Checkpoint
Regulation Of Exit From Mitosis
Regulation Of Mitotic Metaphase/anaphase Transition
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cell Division
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Protein K11-linked Ubiquitination
Pathways
Phosphorylation of the APC/C
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Antigen processing: Ubiquitination & Proteasome degradation
Separation of Sister Chromatids
Inactivation of APC/C via direct inhibition of the APC/C complex
Cellular Senescence
Mitotic Anaphase
APC/C:Cdc20 mediated degradation of Securin
M Phase
Inactivation of APC/C via direct inhibition of the APC/C complex
Autodegradation of Cdh1 by Cdh1:APC/C
Mitotic Spindle Checkpoint
Class I MHC mediated antigen processing & presentation
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Senescence-Associated Secretory Phenotype (SASP)
Regulation of APC/C activators between G1/S and early anaphase
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Cell Cycle, Mitotic
APC/C-mediated degradation of cell cycle proteins
APC/C:Cdc20 mediated degradation of Cyclin B
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Regulation of mitotic cell cycle
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
Cell Cycle Checkpoints
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
Mitotic Metaphase and Anaphase
Adaptive Immune System
Drugs
Diseases
GWAS
Androgen levels (
22936694
)
Protein-Protein Interactions
44 interactors:
ANAPC10
ANAPC13
APOL1
ATRIP
BCAS3
BYSL
CCDC24
CCDC36
CDC16
CDH1
CDT1
CEP44
COIL
CRACR2A
CTBP1
CYB5R2
DLX6-AS1
EIF5A2
FAM9B
FBXO5
GORASP2
HEMK1
INCA1
INPP5J
KCTD6
KDM1A
LZTS2
MAPK3
OPTN
PNMA5
RAC1
RAD54B
RBM15B
RBPMS
RSL24D1
SIAH1
SLC52A2
SOX5
SPERT
SSX2IP
SUV39H1
TRIM27
TSC22D4
UBE2S
118 interactors:
ABT1
ACP6
ANKRD36B
AP1M1
ASB6
ATF7
AURKAIP1
BAG6
BARD1
BCL2A1
BET1
BLOC1S2
BYSL
C12orf10
C14orf105
C16orf72
C19orf57
C20orf195
C8orf33
CADPS
CCDC106
CCDC116
CCDC70
CDC23
CDC42EP4
CDCA7L
CENPL
CEP57L1
CEP95
CHRAC1
CLCN1
CMTM6
COL20A1
CSDE1
CWF19L2
DAPK2
DAXX
DENND2D
DNAJC15
DNAJC4
EBNA1BP2
ECH1
EIF3G
FAM161A
FASTKD3
FCHSD2
FERD3L
GFOD1
GOPC
GPX1
GSTK1
ISCU
LIN7A
LNX1
LOC728175
LYRM2
MAB21L3
MFAP1
MOB1A
MORF4L1
MORF4L2
MRPL10
MRPL28
MRPL9
MYO15B
NDE1
NDUFB10
NEBL
NOL4
PAGE1
PAGE3
PHYH
PIN4
POLL
PPP1R18
PRPF3
PSMD14
PTRH1
RAB17
RAD51B
RBM17
RBM23
RMND1
RPL9
RSL24D1
RUSC1
SDCBP
SDCBP2
SERPINE2
SFN
SLC16A3
SLPI
SMN2
SNAP29
SNAP47
SNX20
STK3
SUCLA2
SYT17
TBRG4
TCEA2
TCEANC
TCEB3
TGFBI
TRMT61B
TSG101
TUFM
TXN2
UBE2E2
URB1-AS1
XRCC4
YARS2
ZCCHC10
ZGPAT
ZNF41
ZNF410
ZNF567
ZNF614
Entrez ID
8697
171483
HPRD ID
07221
15955
Ensembl ID
ENSG00000094880
ENSG00000177138
Uniprot IDs
Q9UJX2
Q8IZU0
Q8N7Z8
PDB IDs
Enriched GO Terms of Interacting Partners
?
Protein K11-linked Ubiquitination
Cell Cycle
Regulation Of Organelle Organization
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Mitotic Cell Cycle
Protein Polyubiquitination
Regulation Of Ubiquitin-protein Transferase Activity
Cell Cycle Process
Mitotic Nuclear Division
Regulation Of Cellular Protein Metabolic Process
Mitotic Cell Cycle Process
Regulation Of Chromosome Organization
Organelle Organization
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Cell Division
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Transferase Activity
Positive Regulation Of Protein Modification Process
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Chromosome Organization
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Ubiquitination
Regulation Of Cellular Component Organization
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Transferase Activity
Protein Ubiquitination
Cell Cycle Checkpoint
Protein Modification By Small Protein Conjugation
Activation Of Anaphase-promoting Complex Activity
Regulation Of Mitotic Sister Chromatid Separation
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Regulation Of Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Mitochondrial Translation
Organelle Organization
Translational Elongation
Vesicle Organization
Gene Expression
Mitochondrion Organization
Synaptic Vesicle Priming
Mitochondrial Translational Elongation
Translation
Establishment Of Vesicle Localization
Vesicle Localization
Ribonucleoprotein Complex Biogenesis
Establishment Of Organelle Localization
Cellular Component Assembly
Cellular Metabolic Process
Synaptic Vesicle Transport
Mitochondrial Translational Initiation
Mitochondrial Translational Termination
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Extracellular Vesicular Exosome Assembly
Cellular Macromolecular Complex Assembly
Organelle Localization
Translational Termination
RNA Metabolic Process
Translational Initiation
Cellular Response To Stress
Apoptotic Signaling Pathway
Cellular Response To DNA Damage Stimulus
Membrane Organization
Protein Polyubiquitination
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Exosomal Secretion
Regulation Of Exosomal Secretion
Synaptic Vesicle Fusion To Presynaptic Membrane
Cellular Process
Cellular Protein Complex Disassembly
Intrinsic Apoptotic Signaling Pathway
Ribosome Biogenesis
Neurotransmitter Secretion
Macromolecule Biosynthetic Process
Vesicle Fusion
Pigmentation
Protein Complex Disassembly
Synaptic Vesicle Exocytosis
Viral Process
Cellular Pigmentation
Tagcloud
?
34c
annexin
arrest
atlas
basal
breast
ccnd1
cdk4
cdk6
downregulated
ectopic
g2
incorporation
inducing
influenced
mediator
microrna
mimicked
mir
mirna
mirnas
mitotic
prkca
qpcr
sirnas
suppressed
suppressor
tcga
thymidine
Tagcloud (Difference)
?
34c
annexin
arrest
atlas
basal
breast
ccnd1
cdk4
cdk6
downregulated
ectopic
g2
incorporation
inducing
influenced
mediator
microrna
mimicked
mir
mirna
mirnas
mitotic
prkca
qpcr
sirnas
suppressed
suppressor
tcga
thymidine
Tagcloud (Intersection)
?