FAM9B and TOM1L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM9B	TOM1L2
Description		family with sequence similarity 9 member B	target of myb1 like 2 membrane trafficking protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleus Nucleoplasm Chromosome Cytoplasm	Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding Clathrin Binding Phosphatidylinositol Binding Ubiquitin Binding
	Biological Process	Spermatid Development Meiotic Cell Cycle	Signal Transduction Protein Transport Negative Regulation Of Mitotic Nuclear Division
Pathways
Drugs
Diseases
GWAS		Age at voice drop ( 27182965) Androgen levels ( 22936694) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 28869591 30598549) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965 29146897) Metabolite levels ( 23823483)	Hip index ( 34021172) Schizophrenia ( 25056061 28991256 29483656) TB-LM or TBLH-BMD (pleiotropy) ( 28743860) Total body bone mineral density ( 29304378) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		140 interacting genes: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BAIAP2L2 BARD1 BCL2A1 BET1 BLOC1S2 BRME1 BYSL C8orf33 CADPS CCDC106 CCDC116 CCDC198 CCDC70 CDC23 CDC37 CDC42EP4 CDCA7L CDSN CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DGUOK DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G ELOA FAM161A FAM9A FASTKD3 FCHSD2 FERD3L FNDC11 GFOD1 GOPC GPX1 GRAMD4 GSTK1 HAPSTR1 HNRNPLL IBSP ISCU JAZF1 LBX1 LIN7A LINC02363 LMNA LNX1 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MRRF MYG1 MYO15B NDE1 NDUFB10 NEBL NOL4 NOTO PAGE1 PAGE3 PHYH PIN4 POLL PPARA PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RNF8 RPL9 RSL24D1 RUBCN RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMARCB1 SMN1 SMN2 SNAP29 SNAP47 SNX20 SRRM4 STK3 SUCLA2 SURF6 SYT17 TBC1D25 TBRG4 TCEA2 TCEANC TGFBI TOM1L2 TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 WT1 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614	15 interacting genes: APP BBS4 BBS5 BBS9 FAM9B LAPTM5 MAP3K1 MYO6 NEDD4 RNF11 RNF26 SMURF1 UBC WBP2 WWP2
Entrez ID		171483	146691
HPRD ID		15955	18213
Ensembl ID		ENSG00000177138	ENSG00000175662
Uniprot IDs		Q8IZU0	B7Z2U2 B7Z671 F5H3S6 Q6ZVM7
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Mitochondrial Matrix RNA Binding	BBSome Establishment Of Protein Localization Ciliary Membrane Modification-dependent Protein Catabolic Process Establishment Of Protein Localization To Vacuole Ubiquitin Protein Ligase Activity Potassium Channel Inhibitor Activity Protein Targeting To Vacuole Protein Ubiquitination Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Potassium Ion Export Across Plasma Membrane Progesterone Receptor Signaling Pathway Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Transport Protein Localization To Vacuole Receptor Catabolic Process Establishment Of Melanosome Localization Pericentriolar Material Melanosome Transport Pigment Granule Transport Ubiquitin Ligase Complex Post-translational Protein Modification Protein Polyubiquitination Negative Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Catabolic Process Pigment Granule Localization Melanosome Localization Ubiquitin-dependent Protein Catabolic Process Centriolar Satellite Intracellular Protein Localization Protein Targeting To Lysosome Negative Regulation Of Potassium Ion Transport Establishment Of Protein Localization To Organelle Ciliary Transition Zone Protein Localization To Organelle Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Minus-end Directed Microfilament Motor Activity Macromolecule Catabolic Process Vacuolar Transport Formation Of Structure Involved In A Symbiotic Process Induction Of Programmed Cell Death Negative Regulation Of Pre-B Cell Receptor Expression Positive Regulation Of Lysosomal Membrane Permeability Engulfment Of Target By Autophagosome Fructose:sodium Symporter Activity
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