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CDC23 and SMARCB1
Number of citations of the paper that reports this interaction (PubMedID
27229929
)
45
Data Source:
BioGRID
(two hybrid)
CDC23
SMARCB1
Description
cell division cycle 23
SWI/SNF related BAF chromatin remodeling complex subunit B1
Image
GO Annotations
Cellular Component
Nucleoplasm
Anaphase-promoting Complex
Cytosol
Nuclear Chromosome
Kinetochore
Chromatin
Fibrillar Center
XY Body
Nucleus
Nucleoplasm
Nucleolus
Nuclear Matrix
SWI/SNF Complex
RSC-type Complex
Protein-containing Complex
Brahma Complex
Germ Cell Nucleus
NpBAF Complex
NBAF Complex
BBAF Complex
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
RNA Polymerase I Core Promoter Sequence-specific DNA Binding
P53 Binding
DNA Binding
Transcription Coactivator Activity
Protein Binding
Tat Protein Binding
Nucleosomal DNA Binding
Identical Protein Binding
Biological Process
Mitotic Cell Cycle
Ubiquitin-dependent Protein Catabolic Process
Mitotic Metaphase Chromosome Alignment
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Regulation Of Exit From Mitosis
Regulation Of Mitotic Cell Cycle
Protein Ubiquitination
Regulation Of Mitotic Metaphase/anaphase Transition
Anaphase-promoting Complex-dependent Catabolic Process
Positive Regulation Of Mitotic Metaphase/anaphase Transition
Cell Division
Regulation Of Meiotic Cell Cycle
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein Branched Polyubiquitination
RNA Polymerase I Preinitiation Complex Assembly
Blastocyst Development
Blastocyst Hatching
Chromatin Organization
Nucleosome Disassembly
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Negative Regulation Of Cell Population Proliferation
DNA Integration
Regulation Of Mitotic Metaphase/anaphase Transition
Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Host-mediated Activation Of Viral Transcription
Positive Regulation Of T Cell Differentiation
Positive Regulation Of Cell Differentiation
Positive Regulation Of Myoblast Differentiation
Transcription Initiation-coupled Chromatin Remodeling
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of G0 To G1 Transition
Hepatocyte Differentiation
Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Positive Regulation Of Stem Cell Population Maintenance
Positive Regulation Of Glucose Mediated Signaling Pathway
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Double-strand Break Repair
Regulation Of Nucleotide-excision Repair
Pathways
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
Assembly of the pre-replicative complex
CDK-mediated phosphorylation and removal of Cdc6
Transcriptional Regulation by VENTX
Aberrant regulation of mitotic exit in cancer due to RB1 defects
Antigen processing: Ubiquitination & Proteasome degradation
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of MITF-M-dependent genes involved in pigmentation
Regulation of MITF-M-dependent genes involved in pigmentation
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Formation of the canonical BAF (cBAF) complex
Formation of the polybromo-BAF (pBAF) complex
Formation of the embryonic stem cell BAF (esBAF) complex
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Resting heart rate (
27798624
)
Dilated cardiomyopathy (
33677556
)
Dilated cardiomyopathy (MTAG) (
33495596
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Fractional shortening (
29403010
)
Hypertrophic cardiomyopathy (
33495596
)
Hypertrophic cardiomyopathy (MTAG) (
33495596
)
IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) (
28878392
)
IgG digalactosylation phenotypes (multivariate analysis) (
28878392
)
IgG disialylation phenotypes (multivariate analysis) (
28878392
)
IgG fucosylation phenotypes (multivariate analysis) (
28878392
)
IgG galactosylation phenotypes (multivariate analysis) (
28878392
)
IgG glycosylation (
23382691
)
IgG monogalactosylation phenotypes (multivariate analysis) (
28878392
)
IgG N-glycosylation phenotypes (multivariate analysis) (
28878392
32128391
)
IgG sialylation phenotypes (multivariate analysis) (
28878392
)
Left ventricle wall thickness (
33495596
)
Left ventricular end-systolic volume (
33495596
)
Left ventricular global circumferential strain (
33495596
)
Left ventricular global radial strain (
33495596
)
Left ventricular mass to end-diastolic volume ratio (
33495596
)
N-glycan levels (
31163085
)
Interacting Genes
78 interacting genes:
ANAPC10
ANKRD11
APOL1
ATRIP
BCAS3
BEGAIN
BYSL
C21orf91
CBY2
CCDC125
CCDC24
CCDC33
CDC16
CDT1
CEP44
CERCAM
COIL
CRACR2A
CRTC2
CTBP1
CYB5R2
DCLK1
DEPDC1B
DISC1
DLX6-AS1
EIF5A2
FAM9B
FOXN1
GORASP2
GPRASP3
GTPBP8
HEMK1
IHO1
INCA1
INO80E
INPP5J
KCTD6
KRT36
LHX3
LZTS1
LZTS2
MAGED1
MAPK3
NAB2
NRBF2
NUP54
OPTN
PFKFB4
PIH1D2
PNMA5
POU6F2
PROSER3
PRPF31
PRR22
RAC1
RAD54B
RBM15B
RBP3
RBPMS
RSL24D1
RUNX1T1
SIAH1
SLC52A2
SMARCB1
SMUG1
SORBS3
SOX5
SPAG8
SSX2IP
STX2
SUV39H1
TEPSIN
TNIP1
TRIM27
TSC22D4
UBE2S
USP54
ZMAT1
111 interacting genes:
ABI2
AKT1
APP
ARL11
ATP5F1A
BCL2L11
BHLHE40
BLZF1
CALR
CAMK2D
CCDC120
CCDC33
CD69
CDC23
CDX2
CEBPB
CHFR
CXCL11
CYB5D2
DNAJA3
DPH6
EZH2
FAM90A1
FAM9B
FUS
GADD45G
GATA1
GFAP
GOLGA2
HGS
HNRNPM
HOMEZ
HOOK2
HSF2BP
HSFY1
IHO1
IKZF3
IL16
KCTD9
KLC3
KLF1
KMT2B
KMT2C
KPNA6
KRT15
KRT19
KRT6A
KRT6B
KRT6C
LDOC1
LENG8
LNX2
LY96
LZTS2
MAP1LC3B
MAP3K20
MAPK8IP2
MBIP
MCPH1
MECP2
MESD
MIF4GD
MRPL53
MXI1
MYC
NCK2
NONO
NR0B2
NR3C1
OSGIN1
OTX2
PDPK1
PICK1
PPP1CC
PPP1R15A
PRKAB2
PSMB1
RAN
RB1
RELB
RINT1
RPN1
RPS6KA5
RUSC1
RXRA
SAXO1
SIN3B
SMARCA4
SRC
TACC2
TAF1D
TASOR2
TEKT5
TFIP11
TLE5
TNFAIP1
TNRC6A
TP53
TRIM14
TRIM27
TRIM35
TSC22D4
UBQLN4
UBR5
VIM
XPO1
YEATS4
ZC3H11A
ZDHHC17
ZNF398
ZNF688
Entrez ID
8697
6598
HPRD ID
07221
03364
Ensembl ID
ENSG00000094880
ENSG00000099956
Uniprot IDs
Q9UJX2
G5E975
Q12824
Q9H836
PDB IDs
4UI9
5A31
5G04
5G05
5KHR
5KHU
5L9T
5L9U
5LCW
6Q6G
6Q6H
6TLJ
6TM5
6TNT
8PKP
8TAR
8TAU
9GAW
5AJ1
5GJK
5L7A
5L7B
6AX5
6KAG
6KZ7
6LTH
6LTJ
6LZP
6UCH
7VDV
7Y8R
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Nucleus
Identical Protein Binding
Regulation Of Transcription By RNA Polymerase II
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Protein Binding
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Gene Expression
Nucleoplasm
Organelle Organization
Protein-containing Complex
Positive Regulation Of Macromolecule Biosynthetic Process
Cytoskeleton Organization
Intermediate Filament Organization
Positive Regulation Of Macromolecule Metabolic Process
Supramolecular Fiber Organization
Regulation Of Primary Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Biosynthetic Process
Chromatin
Regulation Of Metabolic Process
Intermediate Filament Cytoskeleton Organization
Protein Domain Specific Binding
Intermediate Filament-based Process
Developmental Process
Negative Regulation Of Macromolecule Biosynthetic Process
Lymphocyte Apoptotic Process
Structural Constituent Of Cytoskeleton
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Cell Cycle
Negative Regulation Of Biosynthetic Process
Regulation Of Glial Cell Proliferation
Regulation Of Programmed Cell Death
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Cytosol
Negative Regulation Of Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Cellular Response To Stress
Cellular Developmental Process
Positive Regulation Of RNA Metabolic Process
Signal Complex Assembly
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Tagcloud (Intersection)
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