FAM9B and POLL

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		FAM9B	POLL
Description		family with sequence similarity 9 member B	DNA polymerase lambda
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleus Nucleoplasm Chromosome Cytoplasm	Nucleus Nucleoplasm Chromosome Site Of Double-strand Break
	Molecular Function	Protein Binding	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Transferase Activity Nucleotidyltransferase Activity Lyase Activity DNA Polymerase Activity Metal Ion Binding 5'-deoxyribose-5-phosphate Lyase Activity
	Biological Process	Spermatid Development Meiotic Cell Cycle	Double-strand Break Repair Via Homologous Recombination DNA Replication DNA Repair Base-excision Repair, Gap-filling Nucleotide-excision Repair Double-strand Break Repair Via Nonhomologous End Joining DNA Damage Response Somatic Hypermutation Of Immunoglobulin Genes DNA Biosynthetic Process
Pathways			Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS		Age at voice drop ( 27182965) Androgen levels ( 22936694) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 28869591 30598549) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965 29146897) Metabolite levels ( 23823483)
Interacting Genes		140 interacting genes: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BAIAP2L2 BARD1 BCL2A1 BET1 BLOC1S2 BRME1 BYSL C8orf33 CADPS CCDC106 CCDC116 CCDC198 CCDC70 CDC23 CDC37 CDC42EP4 CDCA7L CDSN CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DGUOK DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G ELOA FAM161A FAM9A FASTKD3 FCHSD2 FERD3L FNDC11 GFOD1 GOPC GPX1 GRAMD4 GSTK1 HAPSTR1 HNRNPLL IBSP ISCU JAZF1 LBX1 LIN7A LINC02363 LMNA LNX1 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MRRF MYG1 MYO15B NDE1 NDUFB10 NEBL NOL4 NOTO PAGE1 PAGE3 PHYH PIN4 POLL PPARA PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RNF8 RPL9 RSL24D1 RUBCN RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMARCB1 SMN1 SMN2 SNAP29 SNAP47 SNX20 SRRM4 STK3 SUCLA2 SURF6 SYT17 TBC1D25 TBRG4 TCEA2 TCEANC TGFBI TOM1L2 TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 WT1 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614	42 interacting genes: APP ATM CCNDBP1 CDK1 CDK2 CMTM5 FAM9B FSD2 GOLGA6L9 HMBOX1 HUWE1 KRT16 KRT19 KRT27 KRT40 KRTAP10-3 KRTAP10-7 LCN2 LDOC1 MAGEA12 MAGEA2 MAGEA2B MAL2 MCC MDFI PCNA PICK1 PNMA1 PRKD3 REV1 RPA1 SSX2IP TFCP2 TFIP11 TNFRSF10D TRIM23 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H ZRANB1
Entrez ID		171483	27343
HPRD ID		15955	09394
Ensembl ID		ENSG00000177138	ENSG00000166169
Uniprot IDs		Q8IZU0	A8K860 B4DE17 Q5JQP8 Q9UGP5
PDB IDs			1NZP 1RZT 1XSL 1XSN 1XSP 2BCQ 2BCR 2BCS 2BCU 2BCV 2GWS 2JW5 2PFN 2PFO 2PFP 2PFQ 3C5F 3C5G 3HW8 3HWT 3HX0 3MDA 3MDC 3MGH 3MGI 3PML 3PMN 3PNC 3UPQ 3UQ0 3UQ2 4FO6 4K4G 4K4H 4K4I 4X5V 4XA5 4XQ8 4XRH 4XUS 5CA7 5CB1 5CHG 5CJ7 5CP2 5CR0 5CWR 5DDM 5DDY 5DKW 5III 5IIJ 5IIK 5IIL 5IIM 5IIN 5IIO 5W4G 7M07 7M08 7M09 7M0A 7M0B 7M0C 7M0D 7M0E 7M43 7M44 7M45 7M46 7M47 7M48 7M49 7M4A 7M4B 7M4C 7M4D 7M4E 7M4F 7M4G 7M4H 7M4I 7M4J 7M4K 7M4L 7UN7 8U0O
Enriched GO Terms of Interacting Partners?		Protein Binding Mitochondrial Matrix RNA Binding	Ubiquitin Conjugating Enzyme Activity Telomere Maintenance Chromosome, Telomeric Region Keratin Filament Protein K48-linked Ubiquitination Telomere Organization Ubiquitin-protein Transferase Activity DNA Biosynthetic Process Intermediate Filament Post-translational Protein Modification Protein Polyubiquitination Nucleus DNA Metabolic Process Protein Monoubiquitination Structural Constituent Of Skin Epidermis Cellular Senescence Cyclin-dependent Protein Kinase Activity Chromosome Organization DNA Repair DNA Replication Intermediate Filament Organization Protein Localization To Site Of Double-strand Break Negative Regulation Of Protein Acetylation Negative Regulation Of Transcription By RNA Polymerase II Protein Modification Process Histone Kinase Activity Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process DNA Damage Response Protein Ubiquitination Protection From Non-homologous End Joining At Telomere Cellular Response To Reactive Oxygen Species Positive Regulation Of DNA Replication Positive Regulation Of Protein Ubiquitination PML Body Cyclin-dependent Protein Kinase Holoenzyme Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Modification By Small Protein Conjugation Cellular Response To X-ray Negative Regulation Of Protein Sumoylation Male Germ Cell Nucleus Positive Regulation Of Post-translational Protein Modification Ubiquitin-dependent Protein Catabolic Process Nucleoplasm Epithelial Cell Differentiation Modification-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Protein Binding DNA Strand Resection Involved In Replication Fork Processing Telomere Maintenance In Response To DNA Damage
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