FAM9B and DGUOK

Number of citations of the paper that reports this interaction (PubMedID 26871637)
43

Data Source:
BioGRID (two hybrid)

		FAM9B	DGUOK
Description		family with sequence similarity 9 member B	deoxyguanosine kinase
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleus Nucleoplasm Chromosome Cytoplasm	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Protein Binding	Nucleotide Binding Deoxyadenosine Kinase Activity Deoxyguanosine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Deoxynucleoside Kinase Activity
	Biological Process	Spermatid Development Meiotic Cell Cycle	Nucleobase-containing Compound Metabolic Process Guanosine Metabolic Process Negative Regulation Of Neuron Projection Development Mitochondrial ATP Synthesis Coupled Electron Transport DGTP Metabolic Process Purine Deoxyribonucleoside Metabolic Process DAMP Salvage Carbohydrate Derivative Metabolic Process
Pathways			Purine salvage
Drugs
Diseases			Mitochondrial DNA depletion syndrome (MDS)
GWAS		Age at voice drop ( 27182965) Androgen levels ( 22936694) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 28869591 30598549) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965 29146897) Metabolite levels ( 23823483)	Dialysis-related mortality ( 21546767) Systemic lupus erythematosus ( 23273568)
Interacting Genes		140 interacting genes: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BAIAP2L2 BARD1 BCL2A1 BET1 BLOC1S2 BRME1 BYSL C8orf33 CADPS CCDC106 CCDC116 CCDC198 CCDC70 CDC23 CDC37 CDC42EP4 CDCA7L CDSN CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DGUOK DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G ELOA FAM161A FAM9A FASTKD3 FCHSD2 FERD3L FNDC11 GFOD1 GOPC GPX1 GRAMD4 GSTK1 HAPSTR1 HNRNPLL IBSP ISCU JAZF1 LBX1 LIN7A LINC02363 LMNA LNX1 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MRRF MYG1 MYO15B NDE1 NDUFB10 NEBL NOL4 NOTO PAGE1 PAGE3 PHYH PIN4 POLL PPARA PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RNF8 RPL9 RSL24D1 RUBCN RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMARCB1 SMN1 SMN2 SNAP29 SNAP47 SNX20 SRRM4 STK3 SUCLA2 SURF6 SYT17 TBC1D25 TBRG4 TCEA2 TCEANC TGFBI TOM1L2 TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 WT1 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614	4 interacting genes: APP FAM9B LIG4 PXN
Entrez ID		171483	1716
HPRD ID		15955	03273
Ensembl ID		ENSG00000177138	ENSG00000114956
Uniprot IDs		Q8IZU0	E5KSL5 Q16854
PDB IDs			2OCP
Enriched GO Terms of Interacting Partners?		Protein Binding Mitochondrial Matrix RNA Binding	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Central Nervous System Development Regulation Of Response To Calcium Ion Cell Activation Involved In Immune Response Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cellular Response To Metal Ion Low-density Lipoprotein Particle Mediated Signaling Establishment Of Integrated Proviral Latency DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency DNA Ligase Activity DN2 Thymocyte Differentiation Positive Regulation Of Cellular Component Organization Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission Regulation Of Neuron Apoptotic Process NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Nucleotide-excision Repair, DNA Gap Filling Axon Choice Point Recognition DNA-dependent Protein Kinase-DNA Ligase 4 Complex Heparan Sulfate Binding Signaling Receptor Activator Activity
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