FAM9B and LIN7A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		FAM9B	LIN7A
Description		family with sequence similarity 9 member B	lin-7 cell polarity scaffold A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleus Nucleoplasm Chromosome Cytoplasm	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Membrane Basolateral Plasma Membrane Synapse Postsynaptic Membrane Extracellular Exosome Anchoring Junction MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane
	Molecular Function	Protein Binding	Protein Binding Protein-macromolecule Adaptor Activity L27 Domain Binding
	Biological Process	Spermatid Development Meiotic Cell Cycle	Exocytosis Neurotransmitter Secretion Regulation Of Synaptic Assembly At Neuromuscular Junction Protein Transport Synaptic Vesicle Transport Inner Ear Development Protein-containing Complex Assembly
Pathways			Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS		Age at voice drop ( 27182965) Androgen levels ( 22936694) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 28869591 30598549) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965 29146897) Metabolite levels ( 23823483)	Age-related cataracts (age at onset) ( 25352737) Dental caries ( 23259602)
Interacting Genes		140 interacting genes: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BAIAP2L2 BARD1 BCL2A1 BET1 BLOC1S2 BRME1 BYSL C8orf33 CADPS CCDC106 CCDC116 CCDC198 CCDC70 CDC23 CDC37 CDC42EP4 CDCA7L CDSN CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DGUOK DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G ELOA FAM161A FAM9A FASTKD3 FCHSD2 FERD3L FNDC11 GFOD1 GOPC GPX1 GRAMD4 GSTK1 HAPSTR1 HNRNPLL IBSP ISCU JAZF1 LBX1 LIN7A LINC02363 LMNA LNX1 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MRRF MYG1 MYO15B NDE1 NDUFB10 NEBL NOL4 NOTO PAGE1 PAGE3 PHYH PIN4 POLL PPARA PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RNF8 RPL9 RSL24D1 RUBCN RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMARCB1 SMN1 SMN2 SNAP29 SNAP47 SNX20 SRRM4 STK3 SUCLA2 SURF6 SYT17 TBC1D25 TBRG4 TCEA2 TCEANC TGFBI TOM1L2 TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 WT1 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614	25 interacting genes: ABCA1 ADGRB1 APP BAIAP2 CASK CHRD DLG2 DLG3 DLG4 DNAJC5 ECM1 FAM9B GOLGA2 GRIN2B KCNJ12 MDFI MPP2 MPP3 MPP7 NOTCH2NLA PALS1 PALS2 SLC6A12 VANGL2 ZYX
Entrez ID		171483	8825
HPRD ID		15955	04542
Ensembl ID		ENSG00000177138	ENSG00000111052
Uniprot IDs		Q8IZU0	O14910
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Mitochondrial Matrix RNA Binding	Cell-cell Junction Adherens Junction Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Cell Polarity Positive Regulation Of Excitatory Postsynaptic Potential Protein Localization To Cell Junction Plasma Membrane Regulation Of Synaptic Plasticity Postsynaptic Density Membrane Modulation Of Excitatory Postsynaptic Potential Basolateral Plasma Membrane Postsynaptic Density Protein Localization To Synapse Synaptic Membrane Dendritic Spine Modulation Of Chemical Synaptic Transmission Neuromuscular Junction PDZ Domain Binding Cellular Component Assembly Neuron Projection Protein Tetramerization Ionotropic Glutamate Receptor Signaling Pathway Ionotropic Glutamate Receptor Binding Presynapse Organelle Cell Adhesion Regulation Of Nervous System Process Dendritic Shaft Protein Complex Oligomerization Ligand-gated Ion Channel Signaling Pathway NMDA Selective Glutamate Receptor Signaling Pathway Cell Projection Receptor Localization To Synapse Receptor Clustering Glutamate Receptor Signaling Pathway Positive Regulation Of Synaptic Transmission Regulation Of Synapse Organization GMP Kinase Activity Regulation Of Cell Communication Regulation Of Signaling Regulation Of Neuronal Synaptic Plasticity Chemical Synaptic Transmission Intracellular Protein Localization Trans-synaptic Signaling GDP Metabolic Process Synaptic Signaling Juxtaparanode Region Of Axon Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Acetylcholine Receptor Binding
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