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CDC23 and RBP3
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
CDC23
RBP3
Description
cell division cycle 23
retinol binding protein 3
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Anaphase-promoting Complex
Cytosol
Extracellular Region
Extracellular Space
Interphotoreceptor Matrix
Cone Matrix Sheath
Extracellular Vesicle
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Retinoid Binding
Protein Binding
Serine-type Peptidase Activity
Retinal Binding
Retinol Binding
Biological Process
Mitotic Cell Cycle
Ubiquitin-dependent Protein Catabolic Process
Mitotic Metaphase Chromosome Alignment
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Regulation Of Exit From Mitosis
Regulation Of Mitotic Cell Cycle
Protein Ubiquitination
Regulation Of Mitotic Metaphase/anaphase Transition
Anaphase-promoting Complex-dependent Catabolic Process
Positive Regulation Of Mitotic Metaphase/anaphase Transition
Cell Division
Regulation Of Meiotic Cell Cycle
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein Branched Polyubiquitination
Retinoid Metabolic Process
Proteolysis
Lipid Metabolic Process
Visual Perception
Pathways
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
Assembly of the pre-replicative complex
CDK-mediated phosphorylation and removal of Cdc6
Transcriptional Regulation by VENTX
Aberrant regulation of mitotic exit in cancer due to RB1 defects
Antigen processing: Ubiquitination & Proteasome degradation
The retinoid cycle in cones (daylight vision)
The canonical retinoid cycle in rods (twilight vision)
Drugs
Lapachone
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Resting heart rate (
27798624
)
Corneal curvature (
24963161
)
Macular thickness (
30535121
)
Interacting Genes
78 interacting genes:
ANAPC10
ANKRD11
APOL1
ATRIP
BCAS3
BEGAIN
BYSL
C21orf91
CBY2
CCDC125
CCDC24
CCDC33
CDC16
CDT1
CEP44
CERCAM
COIL
CRACR2A
CRTC2
CTBP1
CYB5R2
DCLK1
DEPDC1B
DISC1
DLX6-AS1
EIF5A2
FAM9B
FOXN1
GORASP2
GPRASP3
GTPBP8
HEMK1
IHO1
INCA1
INO80E
INPP5J
KCTD6
KRT36
LHX3
LZTS1
LZTS2
MAGED1
MAPK3
NAB2
NRBF2
NUP54
OPTN
PFKFB4
PIH1D2
PNMA5
POU6F2
PROSER3
PRPF31
PRR22
RAC1
RAD54B
RBM15B
RBP3
RBPMS
RSL24D1
RUNX1T1
SIAH1
SLC52A2
SMARCB1
SMUG1
SORBS3
SOX5
SPAG8
SSX2IP
STX2
SUV39H1
TEPSIN
TNIP1
TRIM27
TSC22D4
UBE2S
USP54
ZMAT1
15 interacting genes:
CDC23
CREB5
CYSRT1
EFEMP2
HOXA1
HR
HSD3B7
KPRP
KRTAP10-5
MGAT5B
NID2
NOTCH1
PLSCR4
POU4F2
SPAG8
Entrez ID
8697
5949
HPRD ID
07221
01581
Ensembl ID
ENSG00000094880
ENSG00000265203
Uniprot IDs
Q9UJX2
P10745
PDB IDs
4UI9
5A31
5G04
5G05
5KHR
5KHU
5L9T
5L9U
5LCW
6Q6G
6Q6H
6TLJ
6TM5
6TNT
8PKP
8TAR
8TAU
9GAW
Enriched GO Terms of Interacting Partners
?
Artery Development
Semicircular Canal Formation
Artery Morphogenesis
Abducens Nerve Formation
Optokinetic Behavior
MAML1-RBP-Jkappa- ICN1 Complex
Apoptotic Process Involved In Embryonic Digit Morphogenesis
Vascular Associated Smooth Muscle Cell Development
Regulation Of Extracellular Matrix Organization
Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation
Vasculogenesis Involved In Coronary Vascular Morphogenesis
Venous Endothelial Cell Differentiation
Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation
Distal Tubule Development
Muscle Tissue Morphogenesis
Regulation Of Smooth Muscle Cell Differentiation
Epidermis Development
Auditory Receptor Cell Fate Commitment
Notch Signaling Involved In Heart Development
Positive Regulation Of Muscle Cell Differentiation
Regulation Of Aorta Morphogenesis
Growth Involved In Heart Morphogenesis
Negative Regulation Of Lymphoid Progenitor Cell Differentiation
Negative Regulation Of Inner Ear Receptor Cell Differentiation
Muscle Cell Development
Chromatin DNA Binding
Epidermal Cell Fate Specification
Endocardium Morphogenesis
Coronary Sinus Valve Morphogenesis
Retinal Cone Cell Differentiation
Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Negative Regulation Of Pro-B Cell Differentiation
Negative Regulation Of Neuron Differentiation
Calcium Ion Binding
Cardiac Right Ventricle Formation
Glomerular Mesangial Cell Development
Cell Migration Involved In Endocardial Cushion Formation
Chemical Synaptic Transmission, Postsynaptic
Foregut Morphogenesis
Compartment Pattern Specification
Mitral Valve Formation
Arterial Endothelial Cell Differentiation
Cellular Response To Tumor Cell
Regulation Of Cell Adhesion Involved In Heart Morphogenesis
Positive Regulation Of Smooth Muscle Cell Differentiation
Tissue Development
Cardiac Vascular Smooth Muscle Cell Development
Negative Regulation Of Extracellular Matrix Constituent Secretion
Epithelium Development
Positive Regulation Of Aorta Morphogenesis
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Tagcloud (Intersection)
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