FAM9B and SMN2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FAM9B	SMN2
Gene Name		family with sequence similarity 9, member B	survival of motor neuron 2, centromeric
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Cajal Body Z Disc SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function		RNA Binding Protein Binding Identical Protein Binding
	Biological Process		Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly Nervous System Development Gene Expression NcRNA Metabolic Process
Pathways			snRNP Assembly Metabolism of non-coding RNA
Drugs
Diseases
GWAS		Androgen levels ( 22936694)
Protein-Protein Interactions		118 interactors: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BARD1 BCL2A1 BET1 BLOC1S2 BYSL C12orf10 C14orf105 C16orf72 C19orf57 C20orf195 C8orf33 CADPS CCDC106 CCDC116 CCDC70 CDC23 CDC42EP4 CDCA7L CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G FAM161A FASTKD3 FCHSD2 FERD3L GFOD1 GOPC GPX1 GSTK1 ISCU LIN7A LNX1 LOC728175 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MYO15B NDE1 NDUFB10 NEBL NOL4 PAGE1 PAGE3 PHYH PIN4 POLL PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RPL9 RSL24D1 RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMN2 SNAP29 SNAP47 SNX20 STK3 SUCLA2 SYT17 TBRG4 TCEA2 TCEANC TCEB3 TGFBI TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 XRCC4 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614	24 interactors: BLOC1S6 BYSL CHTOP DDX20 DHX9 FAM9B FBL GAR1 GEMIN2 HNRNPUL1 POLR1C POLR2A PPIG SMN1 SNRPB SNRPB2 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG TIAL1 VPS28
Entrez ID		171483	6607
HPRD ID		15955	09036
Ensembl ID		ENSG00000177138	ENSG00000205571
Uniprot IDs		Q8IZU0 Q8N7Z8	B4DP61 Q16637
PDB IDs			1G5V 1MHN 2LEH 3S6N 4A4E 4A4G 4GLI
Enriched GO Terms of Interacting Partners?		Mitochondrial Translation Organelle Organization Translational Elongation Vesicle Organization Gene Expression Mitochondrion Organization Synaptic Vesicle Priming Mitochondrial Translational Elongation Translation Establishment Of Vesicle Localization Vesicle Localization Ribonucleoprotein Complex Biogenesis Establishment Of Organelle Localization Cellular Component Assembly Cellular Metabolic Process Synaptic Vesicle Transport Mitochondrial Translational Initiation Mitochondrial Translational Termination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Extracellular Vesicular Exosome Assembly Cellular Macromolecular Complex Assembly Organelle Localization Translational Termination RNA Metabolic Process Translational Initiation Cellular Response To Stress Apoptotic Signaling Pathway Cellular Response To DNA Damage Stimulus Membrane Organization Protein Polyubiquitination Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Cellular Process Cellular Protein Complex Disassembly Intrinsic Apoptotic Signaling Pathway Ribosome Biogenesis Neurotransmitter Secretion Macromolecule Biosynthetic Process Vesicle Fusion Pigmentation Protein Complex Disassembly Synaptic Vesicle Exocytosis Viral Process Cellular Pigmentation	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly RNA Splicing RNA Processing MRNA Processing Ribonucleoprotein Complex Biogenesis NcRNA Metabolic Process MRNA Metabolic Process Ribonucleoprotein Complex Assembly RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Histone MRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Spliceosomal Complex Assembly Cellular Nitrogen Compound Metabolic Process DNA-templated Transcription, Termination Cellular Macromolecular Complex Assembly Nitrogen Compound Metabolic Process Termination Of RNA Polymerase II Transcription MRNA 3'-end Processing RNA 3'-end Processing Cellular Metabolic Process Cellular Component Assembly Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process RRNA Processing RRNA Metabolic Process Metabolic Process Ribosome Biogenesis Histone Glutamine Methylation Cellular Process Transcription, RNA-templated Peptidyl-glutamine Methylation Positive Regulation Of Type I Interferon Production Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway DNA-templated Transcription, Elongation SnoRNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process CRD-mediated MRNA Stabilization Regulation Of Type I Interferon Production Endosome Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Helicase Activity Secretion Of Lysosomal Enzymes Late Endosome To Vacuole Transport Osteoblast Differentiation
Tagcloud ?			atrophy centromeric compensate copies copy degeneration deletions detectable display donor easily exon fails fatal harbor hindering homozygous infant intragenic italian modifier muscular null predictable sma smn1 splice unusually weakness
Tagcloud (Difference) ?			atrophy centromeric compensate copies copy degeneration deletions detectable display donor easily exon fails fatal harbor hindering homozygous infant intragenic italian modifier muscular null predictable sma smn1 splice unusually weakness
Tagcloud (Intersection) ?