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CDC23 and ANAPC10
Number of citations of the paper that reports this interaction (PubMedID
10318877
)
0
Data Source:
HPRD
(in vivo)
CDC23
ANAPC10
Description
cell division cycle 23
anaphase promoting complex subunit 10
Image
GO Annotations
Cellular Component
Nucleoplasm
Anaphase-promoting Complex
Cytosol
Nucleoplasm
Anaphase-promoting Complex
Cytoplasm
Cytosol
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Protein Binding
Biological Process
Mitotic Cell Cycle
Ubiquitin-dependent Protein Catabolic Process
Mitotic Metaphase Chromosome Alignment
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Regulation Of Exit From Mitosis
Regulation Of Mitotic Cell Cycle
Protein Ubiquitination
Regulation Of Mitotic Metaphase/anaphase Transition
Anaphase-promoting Complex-dependent Catabolic Process
Positive Regulation Of Mitotic Metaphase/anaphase Transition
Cell Division
Regulation Of Meiotic Cell Cycle
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein Branched Polyubiquitination
Regulation Of Mitotic Cell Cycle
Protein Ubiquitination
Anaphase-promoting Complex-dependent Catabolic Process
Cell Division
Regulation Of Meiotic Cell Cycle
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein Branched Polyubiquitination
Pathways
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
Assembly of the pre-replicative complex
CDK-mediated phosphorylation and removal of Cdc6
Transcriptional Regulation by VENTX
Aberrant regulation of mitotic exit in cancer due to RB1 defects
Antigen processing: Ubiquitination & Proteasome degradation
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
Assembly of the pre-replicative complex
CDK-mediated phosphorylation and removal of Cdc6
Transcriptional Regulation by VENTX
Aberrant regulation of mitotic exit in cancer due to RB1 defects
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Resting heart rate (
27798624
)
A body shape index (
34021172
)
Adult body size (
32376654
)
Angiotensin-converting enzyme inhibitor intolerance (
28030426
)
Appendicular lean mass (
33097823
)
Brain morphology (MOSTest) (
32665545
)
Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) (
30940143
)
Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) (
30940143
)
Cortical surface area (MOSTest) (
32665545
)
Height (
25429064
31562340
25282103
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Hip circumference (
25673412
)
Hip circumference adjusted for BMI (
34021172
)
Malaria (
31844061
)
Mean corpuscular hemoglobin concentration (
27863252
)
Mean corpuscular volume (
27863252
)
Mean reticulocyte volume (
32888494
)
Monocyte count (
27863252
32888494
)
Monocyte percentage of white cells (
32888494
27863252
)
Reticulocyte fraction of red cells (
32888494
)
Subcortical volume (MOSTest) (
32665545
)
Waist circumference adjusted for body mass index (
34021172
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
26426971
34021172
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
78 interacting genes:
ANAPC10
ANKRD11
APOL1
ATRIP
BCAS3
BEGAIN
BYSL
C21orf91
CBY2
CCDC125
CCDC24
CCDC33
CDC16
CDT1
CEP44
CERCAM
COIL
CRACR2A
CRTC2
CTBP1
CYB5R2
DCLK1
DEPDC1B
DISC1
DLX6-AS1
EIF5A2
FAM9B
FOXN1
GORASP2
GPRASP3
GTPBP8
HEMK1
IHO1
INCA1
INO80E
INPP5J
KCTD6
KRT36
LHX3
LZTS1
LZTS2
MAGED1
MAPK3
NAB2
NRBF2
NUP54
OPTN
PFKFB4
PIH1D2
PNMA5
POU6F2
PROSER3
PRPF31
PRR22
RAC1
RAD54B
RBM15B
RBP3
RBPMS
RSL24D1
RUNX1T1
SIAH1
SLC52A2
SMARCB1
SMUG1
SORBS3
SOX5
SPAG8
SSX2IP
STX2
SUV39H1
TEPSIN
TNIP1
TRIM27
TSC22D4
UBE2S
USP54
ZMAT1
16 interacting genes:
ANAPC11
ANAPC7
CDC16
CDC20
CDC23
CDC27
LIG4
LRP1
LRP2
LRP8
MAPK8IP2
NLRP3
PTEN
SMAD2
SMAD3
TSC22D2
Entrez ID
8697
10393
HPRD ID
07221
16488
Ensembl ID
ENSG00000094880
ENSG00000164162
Uniprot IDs
Q9UJX2
D6RD74
Q9UM13
PDB IDs
4UI9
5A31
5G04
5G05
5KHR
5KHU
5L9T
5L9U
5LCW
6Q6G
6Q6H
6TLJ
6TM5
6TNT
8PKP
8TAR
8TAU
9GAW
1JHJ
4UI9
5A31
5G04
5G05
5KHR
5KHU
5L9T
5L9U
5LCW
6Q6G
6Q6H
6TLJ
6TM5
6TNT
8PKP
8TAR
8TAU
9GAW
Enriched GO Terms of Interacting Partners
?
Anaphase-promoting Complex-dependent Catabolic Process
Anaphase-promoting Complex
Positive Regulation Of Mitotic Metaphase/anaphase Transition
Protein Branched Polyubiquitination
Positive Regulation Of Mitotic Sister Chromatid Separation
Regulation Of Meiotic Cell Cycle
Positive Regulation Of Chromosome Separation
Protein K11-linked Ubiquitination
Regulation Of Sister Chromatid Segregation
Positive Regulation Of Mitotic Nuclear Division
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Regulation Of Chromosome Organization
Regulation Of Chromosome Segregation
Regulation Of Mitotic Sister Chromatid Separation
Proteasomal Protein Catabolic Process
Regulation Of Chromosome Separation
Positive Regulation Of Cellular Component Organization
Regulation Of Reproductive Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Regulation Of Mitotic Metaphase/anaphase Transition
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Protein Catabolic Process
Protein K48-linked Ubiquitination
Metaphase/anaphase Transition Of Cell Cycle
Positive Regulation Of Cell Cycle Phase Transition
Proteolysis Involved In Protein Catabolic Process
Regulation Of Mitotic Nuclear Division
Cell Division
Regulation Of Cellular Component Organization
Positive Regulation Of Mitotic Cell Cycle
Regulation Of Nuclear Division
Regulation Of Mitotic Cell Cycle
Positive Regulation Of Organelle Organization
Regulation Of Organelle Organization
Low-density Lipoprotein Particle Receptor Activity
Regulation Of Mitotic Cell Cycle Phase Transition
Macromolecule Catabolic Process
Cargo Receptor Activity
Regulation Of Cell Cycle
Regulation Of Cell Cycle Phase Transition
Regulation Of Cell Cycle Process
Paraxial Mesoderm Morphogenesis
Positive Regulation Of Cell Cycle Process
Proteolysis
Protein Polyubiquitination
Positive Regulation Of Lysosomal Protein Catabolic Process
Mesoderm Morphogenesis
Positive Regulation Of Cell Cycle
Protein Ubiquitination
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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