Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
CDC23 and GORASP2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CDC23
GORASP2
Gene Name
cell division cycle 23
golgi reassembly stacking protein 2, 55kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Nucleoplasm
Anaphase-promoting Complex
Cytosol
Golgi Membrane
Golgi Apparatus
Membrane
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Biological Process
Mitotic Cell Cycle
Ubiquitin-dependent Protein Catabolic Process
Mitotic Nuclear Division
Mitotic Metaphase Plate Congression
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Mitotic Spindle Assembly Checkpoint
Regulation Of Exit From Mitosis
Regulation Of Mitotic Metaphase/anaphase Transition
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cell Division
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Protein K11-linked Ubiquitination
Mitotic Cell Cycle
Organelle Organization
Pathways
Phosphorylation of the APC/C
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Antigen processing: Ubiquitination & Proteasome degradation
Separation of Sister Chromatids
Inactivation of APC/C via direct inhibition of the APC/C complex
Cellular Senescence
Mitotic Anaphase
APC/C:Cdc20 mediated degradation of Securin
M Phase
Inactivation of APC/C via direct inhibition of the APC/C complex
Autodegradation of Cdh1 by Cdh1:APC/C
Mitotic Spindle Checkpoint
Class I MHC mediated antigen processing & presentation
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Senescence-Associated Secretory Phenotype (SASP)
Regulation of APC/C activators between G1/S and early anaphase
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Cell Cycle, Mitotic
APC/C-mediated degradation of cell cycle proteins
APC/C:Cdc20 mediated degradation of Cyclin B
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Regulation of mitotic cell cycle
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
Cell Cycle Checkpoints
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
Mitotic Metaphase and Anaphase
Adaptive Immune System
Mitotic Prophase
Golgi Cisternae Pericentriolar Stack Reorganization
Cell Cycle, Mitotic
M Phase
Drugs
Diseases
GWAS
Cognitive performance (
19734545
)
Protein-Protein Interactions
44 interactors:
ANAPC10
ANAPC13
APOL1
ATRIP
BCAS3
BYSL
CCDC24
CCDC36
CDC16
CDH1
CDT1
CEP44
COIL
CRACR2A
CTBP1
CYB5R2
DLX6-AS1
EIF5A2
FAM9B
FBXO5
GORASP2
HEMK1
INCA1
INPP5J
KCTD6
KDM1A
LZTS2
MAPK3
OPTN
PNMA5
RAC1
RAD54B
RBM15B
RBPMS
RSL24D1
SIAH1
SLC52A2
SOX5
SPERT
SSX2IP
SUV39H1
TRIM27
TSC22D4
UBE2S
69 interactors:
AAMDC
ACY3
AES
APP
ARL6IP1
ATXN1L
BEND5
BLZF1
C1orf94
CBLB
CCDC153
CDC23
CRYAA
DCTD
DMC1
DPYSL2
DUSP21
EIF2B1
ENOX1
GABPB2
GOLGA2
JADE2
KCTD5
KCTD9
KIFC3
LONRF1
LTBP3
MAP1LC3B
MAPK1
MAPK14
MAPK8
MID2
MIF
MORN2
NME1
NQO2
NUP62
ODC1
PCBD1
PDE9A
PNMA5
PRDX3
PRPS1
PRRC2A
PSMA3
RAB1A
RAB2A
RAD54B
RGS3
RPIA
SCAND1
SELENBP1
STOX1
TCF4
TEKT3
TGFA
TMED10
TMED2
TMED3
TRAF1
TRAF2
TRAF4
TRAF5
TRIM38
TSC22D4
TXLNA
ZBTB14
ZMAT1
ZNF148
Entrez ID
8697
26003
HPRD ID
07221
08303
Ensembl ID
ENSG00000094880
ENSG00000115806
Uniprot IDs
Q9UJX2
B4DKT0
B4DNR1
Q9H8Y8
PDB IDs
3RLE
4EDJ
Enriched GO Terms of Interacting Partners
?
Protein K11-linked Ubiquitination
Cell Cycle
Regulation Of Organelle Organization
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Mitotic Cell Cycle
Protein Polyubiquitination
Regulation Of Ubiquitin-protein Transferase Activity
Cell Cycle Process
Mitotic Nuclear Division
Regulation Of Cellular Protein Metabolic Process
Mitotic Cell Cycle Process
Regulation Of Chromosome Organization
Organelle Organization
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Cell Division
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Transferase Activity
Positive Regulation Of Protein Modification Process
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Chromosome Organization
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Ubiquitination
Regulation Of Cellular Component Organization
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Transferase Activity
Protein Ubiquitination
Cell Cycle Checkpoint
Protein Modification By Small Protein Conjugation
Activation Of Anaphase-promoting Complex Activity
Regulation Of Mitotic Sister Chromatid Separation
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Regulation Of Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Protein Binding
Regulation Of Binding
Positive Regulation Of NF-kappaB Transcription Factor Activity
Golgi Organization
Regulation Of Protein Metabolic Process
Regulation Of Apoptotic Process
Regulation Of MAP Kinase Activity
Regulation Of Cell Death
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cargo Loading Into Vesicle
Regulation Of Kinase Activity
Positive Regulation Of Intracellular Signal Transduction
Protein Transport
Positive Regulation Of Signal Transduction
Regulation Of Protein Kinase Activity
Establishment Of Protein Localization
Intracellular Protein Transport
Regulation Of Protein Homodimerization Activity
Regulation Of MAPK Cascade
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of Metabolic Process
MyD88-independent Toll-like Receptor Signaling Pathway
COPII-coated Vesicle Budding
Regulation Of Nitrogen Compound Metabolic Process
Toll-like Receptor 3 Signaling Pathway
Establishment Of Localization In Cell
Regulation Of Signal Transduction
Positive Regulation Of Cell Proliferation
Negative Regulation Of Cellular Metabolic Process
Protein Complex Assembly
Positive Regulation Of Protein Metabolic Process
Protein Homooligomerization
Toll-like Receptor 4 Signaling Pathway
Cell Death
Death
Positive Regulation Of Protein Serine/threonine Kinase Activity
Protein Localization
Positive Regulation Of Transferase Activity
Cellular Localization
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Apoptotic Process
Protein Ubiquitination
Intracellular Transport
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Transferase Activity
Protein Oligomerization
Endomembrane System Organization
Cell Cycle
Cellular Protein Localization
Tagcloud
?
34c
annexin
arrest
atlas
basal
breast
ccnd1
cdk4
cdk6
downregulated
ectopic
g2
incorporation
inducing
influenced
mediator
microrna
mimicked
mir
mirna
mirnas
mitotic
prkca
qpcr
sirnas
suppressed
suppressor
tcga
thymidine
Tagcloud (Difference)
?
34c
annexin
arrest
atlas
basal
breast
ccnd1
cdk4
cdk6
downregulated
ectopic
g2
incorporation
inducing
influenced
mediator
microrna
mimicked
mir
mirna
mirnas
mitotic
prkca
qpcr
sirnas
suppressed
suppressor
tcga
thymidine
Tagcloud (Intersection)
?