FAM9B and YARS2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		FAM9B	YARS2
Description		family with sequence similarity 9 member B	tyrosyl-tRNA synthetase 2
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleus Nucleoplasm Chromosome Cytoplasm	Mitochondrion Mitochondrial Matrix Cytosol Nuclear Body
	Molecular Function	Protein Binding	TRNA Binding Nucleotide Binding RNA Binding Aminoacyl-tRNA Ligase Activity Tyrosine-tRNA Ligase Activity Protein Binding ATP Binding Ligase Activity Protein Homodimerization Activity L-tyrosine Binding
	Biological Process	Spermatid Development Meiotic Cell Cycle	Translation TRNA Aminoacylation For Protein Translation Tyrosyl-tRNA Aminoacylation TRNA Aminoacylation Mitochondrial Tyrosyl-tRNA Aminoacylation
Pathways			Mitochondrial tRNA aminoacylation
Drugs			Tyrosine
Diseases			Myopathy with lactic acidosis and sideroblastic anaemia (MLASA); Mitochondrial myopathy and sideroblastic anemia
GWAS		Age at voice drop ( 27182965) Androgen levels ( 22936694) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 28869591 30598549) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965 29146897) Metabolite levels ( 23823483)	Diverticular disease ( 30177863) Metabolite levels ( 23823483)
Interacting Genes		140 interacting genes: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BAIAP2L2 BARD1 BCL2A1 BET1 BLOC1S2 BRME1 BYSL C8orf33 CADPS CCDC106 CCDC116 CCDC198 CCDC70 CDC23 CDC37 CDC42EP4 CDCA7L CDSN CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DGUOK DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G ELOA FAM161A FAM9A FASTKD3 FCHSD2 FERD3L FNDC11 GFOD1 GOPC GPX1 GRAMD4 GSTK1 HAPSTR1 HNRNPLL IBSP ISCU JAZF1 LBX1 LIN7A LINC02363 LMNA LNX1 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MRRF MYG1 MYO15B NDE1 NDUFB10 NEBL NOL4 NOTO PAGE1 PAGE3 PHYH PIN4 POLL PPARA PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RNF8 RPL9 RSL24D1 RUBCN RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMARCB1 SMN1 SMN2 SNAP29 SNAP47 SNX20 SRRM4 STK3 SUCLA2 SURF6 SYT17 TBC1D25 TBRG4 TCEA2 TCEANC TGFBI TOM1L2 TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 WT1 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614	3 interacting genes: AGTRAP FAM9B UBC
Entrez ID		171483	51067
HPRD ID		15955	13025
Ensembl ID		ENSG00000177138	ENSG00000139131
Uniprot IDs		Q8IZU0	Q9Y2Z4
PDB IDs			2PID 3ZXI
Enriched GO Terms of Interacting Partners?		Protein Binding Mitochondrial Matrix RNA Binding
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