FAM9B and ECH1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		FAM9B	ECH1
Description		family with sequence similarity 9 member B	enoyl-CoA hydratase 1
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleus Nucleoplasm Chromosome Cytoplasm	Cytoplasm Mitochondrion Mitochondrial Matrix Peroxisome Peroxisomal Matrix Cytosol Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Catalytic Activity Protein Binding Isomerase Activity Delta(3,5)-delta(2,4)-dienoyl-CoA Isomerase Activity
	Biological Process	Spermatid Development Meiotic Cell Cycle	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation
Pathways			Peroxisomal protein import Peroxisomal protein import Mitochondrial protein degradation
Drugs
Diseases
GWAS		Age at voice drop ( 27182965) Androgen levels ( 22936694) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 28869591 30598549) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965 29146897) Metabolite levels ( 23823483)	Blood protein levels ( 30072576) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		140 interacting genes: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BAIAP2L2 BARD1 BCL2A1 BET1 BLOC1S2 BRME1 BYSL C8orf33 CADPS CCDC106 CCDC116 CCDC198 CCDC70 CDC23 CDC37 CDC42EP4 CDCA7L CDSN CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DGUOK DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G ELOA FAM161A FAM9A FASTKD3 FCHSD2 FERD3L FNDC11 GFOD1 GOPC GPX1 GRAMD4 GSTK1 HAPSTR1 HNRNPLL IBSP ISCU JAZF1 LBX1 LIN7A LINC02363 LMNA LNX1 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MRRF MYG1 MYO15B NDE1 NDUFB10 NEBL NOL4 NOTO PAGE1 PAGE3 PHYH PIN4 POLL PPARA PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RNF8 RPL9 RSL24D1 RUBCN RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMARCB1 SMN1 SMN2 SNAP29 SNAP47 SNX20 SRRM4 STK3 SUCLA2 SURF6 SYT17 TBC1D25 TBRG4 TCEA2 TCEANC TGFBI TOM1L2 TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 WT1 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614	13 interacting genes: APP CSTF2 EEF1D EEF1G FAM9B FXR1 FXR2 HTT PAFAH1B3 SERPINB9 STAT3 TIMP1 TLR10
Entrez ID		171483	1891
HPRD ID		15955	02825
Ensembl ID		ENSG00000177138	ENSG00000104823
Uniprot IDs		Q8IZU0	A0A384MR44 Q13011
PDB IDs			2VRE 8SK6
Enriched GO Terms of Interacting Partners?		Protein Binding Mitochondrial Matrix RNA Binding	Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Endopeptidase Activity Positive Regulation Of Catabolic Process Negative Regulation Of Long-term Synaptic Potentiation Peptidase Inhibitor Activity Translation Elongation Factor Activity Negative Regulation Of Peptidase Activity Regulation Of Endopeptidase Activity Positive Regulation Of MRNA Catabolic Process Translation Regulator Activity Protein Heterodimerization Activity Protein Homodimerization Activity Regulation Of Membrane Protein Ectodomain Proteolysis Positive Regulation Of MRNA Metabolic Process Regulation Of MiRNA-mediated Gene Silencing Dentate Gyrus Development Regulation Of Post-transcriptional Gene Silencing Regulation Of Defense Response Regulation Of Tumor Necrosis Factor Production Modulation Of Chemical Synaptic Transmission Positive Regulation Of ATP Metabolic Process Negative Regulation Of Hydrolase Activity Regulation Of MRNA Stability Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Synaptic Plasticity Regulation Of Long-term Synaptic Potentiation Cellular Response To Nerve Growth Factor Stimulus Regulation Of RNA Stability Response To Nerve Growth Factor Amyloid-beta Complex Presynapse Growth Cone Lamellipodium Postsynapse Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Calcium-mediated Signaling MRNA Binding Post-transcriptional Regulation Of Gene Expression Positive Regulation Of Interleukin-1 Beta Production Translational Elongation Regulation Of Carbohydrate Catabolic Process Platelet Alpha Granule Lumen Identical Protein Binding Heat Shock Protein Binding Regulation Of Multicellular Organism Growth
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