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USHBP1 and KPNA2
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
USHBP1
KPNA2
Description
USH1 protein network component harmonin binding protein 1
karyopherin subunit alpha 2
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Membrane
Nuclear Membrane
NLS-dependent Protein Nuclear Import Complex
Host Cell
Molecular Function
Protein Binding
PDZ Domain Binding
RNA Binding
Protein Binding
Nuclear Localization Sequence Binding
Histone Deacetylase Binding
Nuclear Import Signal Receptor Activity
Biological Process
Regulation Of DNA Recombination
DNA Metabolic Process
Protein Import Into Nucleus
NLS-bearing Protein Import Into Nucleus
Protein Transport
Positive Regulation Of Type I Interferon Production
Non-canonical NF-kappaB Signal Transduction
Positive Regulation Of DNA-templated Transcription
Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin
Positive Regulation Of Viral Life Cycle
Pathways
CaMK IV-mediated phosphorylation of CREB
ISG15 antiviral mechanism
NS1 Mediated Effects on Host Pathways
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde
Sensing of DNA Double Strand Breaks
Estrogen-dependent gene expression
SARS-CoV-1 activates/modulates innate immune responses
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS
Mitochondrial DNA copy number (
30704525
)
Brain morphology (MOSTest) (
32665545
)
Feeling lonely (
29500382
)
General risk tolerance (MTAG) (
30643258
)
Loneliness (
29970889
)
Loneliness (MTAG) (
29970889
)
Refractive error (
32231278
)
Regular attendance at a religious group (
29970889
)
Interacting Genes
234 interacting genes:
ABHD11
ABI2
ABLIM1
ACMSD
AIRIM
AKAP9
ANKRD33
ANKRD36BP1
ARFIP2
ARMC5
ARNT2
ASB15
ATP5PO
BCAS2
BCL10
BCL2L11
BET1
BEX2
BEX3
BFSP1
BFSP2
BICRAL
BLOC1S1
BLZF1
BORCS6
BRAT1
BRPF1
C1orf216
C21orf58
CBY2
CCDC116
CCDC120
CCDC121
CCDC146
CCDC148
CCDC187
CCDC196
CCDC197
CCDC22
CCDC24
CCDC28A
CCDC33
CCDC42
CCDC87
CCHCR1
CCNK
CDC37
CDC5L
CDKN1A
CENPP
CEP63
CEP68
CFAP206
CHCHD3
CNNM3
COPS4
COPS6
COPS8
CTNNA3
CTNNBIP1
CTTNBP2NL
CYTH4
DCTN2
DCTN3
DEPP1
DEUP1
DNAAF19
DRC4
DTNB
DYDC1
EIF4E2
ENKD1
ERCC1
EXOC7
EXOC8
FAM107A
FAM110A
FAM124B
FAM161B
FANCG
FATE1
FBF1
FCHSD2
FCRL5
FTL
GATAD2B
GCC1
GEM
GFI1B
GIT2
GMCL2
GNG4
GOLGA6L9
GOLGA8EP
GOLGA8F
GPSM1
GPSM3
GTF2H1
HAUS1
HAUS8
HGS
HMG20A
HMG20B
HYI
IFT20
IL16
IMP3
ING3
INPP1
INTS4
ITGB3BP
KANK2
KANSL1
KIAA0753
KLC3
KLC4
KLHL38
KLHL42
KPNA2
KRT14
KRT15
KRT16
KRT19
KRT20
KRT26
KRT27
KRT28
KRT31
KRT37
KRT38
KRT40
KRT71
KRT75
KRT79
LENG1
LINC00526
MAGEB4
MCCD1
MCM7
MCRS1
MED11
MED28
MED4
MEI4
METTL15
MIIP
MKRN3
MNS1
MOS
MRPS23
MXI1
MYOG
MYOZ1
NCAPH2
NDC80
NDE1
NECAB2
NEFL
NOC4L
NUP62
ODAD3
OIP5
PARVG
PAX6
PBX4
PICK1
PKN1
PKNOX2
PMF1
POLM
POP5
PPP1R12C
PPP1R7
PPP2R5A
PPP2R5D
PRC1
PRKAA2
PRR5
QARS1
RASAL2
RCOR3
RECK
RIBC1
RIBC2
RINT1
RNF20
RTP5
SAPCD2
SAT1
SCNM1
SCT
SEC14L4
SEMA4C
SERTAD3
SH2D4A
SHC3
SMARCD1
SMARCE1
SOHLH1
SPG21
SRI
STX11
SYNJ2BP
TASOR2
TCEANC
TCHP
TEKT1
THADA
THOC1
TIMM13
TPRX1
TRIM54
TRIML2
TSG101
TTC23
TTC9C
TTLL10
TUBGCP4
TXLNA
TXLNB
UBE2W
UBXN11
USH1C
USP2
VPS28
ZBTB42
ZFHX3
ZFYVE26
ZNF417
ZNF483
ZNF655
ZNF688
ZNF765
ZNRF2P1
111 interacting genes:
ACTN1
ACTN4
ANKIB1
AP2B1
APOBEC1
APP
ARL4A
ARL5A
ATXN3
BAG6
BRCA1
BTBD2
CASP2
CCDC107
CDA
CDC42
CDK5RAP3
CHD3
CHEK2
CORO1B
CREB3L3
CREBBP
CSNK1A1
CUL4B
DCPS
DCTN2
DDIT3
EIF4ENIF1
EP300
EPB41
FEZ2
FN1
FTH1
GART
GMCL1
GRB2
GTF2IRD1
H1-0
HAP1
HMG20A
HNRNPC
HOMER2
HOMEZ
HSPA4
IFT20
IMMT
INO80E
ITK
JUN
KLC4
KPNB1
KRT18
KRT40
KRT8
LAMB2
LEF1
LZTS2
MAGED1
MAGEH1
MDFI
MLH1
MORC3
MORF4L1
MVP
NECAB2
NFE2L2
NFKBIB
NMNAT1
NR3C1
NUP153
NUP50
NUP62
NUTM1
OGT
PAX5
PLAG1
PNMA5
PRKD3
PTMA
RAG1
RANBP2
RBM48
RBPMS
RECQL
RELA
RELB
RGL2
RILP
RNMT
SERTAD3
SGK1
SLC2A2
SPRY1
SRPK1
STUB1
SUMO2
TADA2A
TAF3
TAF8
TANK
TBPL2
TP53
TRAF1
TRIM54
TSC22D4
TXNIP
UBR5
USHBP1
ZBTB7B
ZC3H12A
ZNF131
Entrez ID
83878
3838
HPRD ID
18276
02818
Ensembl ID
ENSG00000130307
ENSG00000182481
Uniprot IDs
B4DUE8
G8JLM4
Q8N6Y0
Q8N8Y1
P52292
PDB IDs
1EFX
1QGK
1QGR
3FEX
3FEY
3WPT
4E4V
4WV6
5H43
7CRU
7N8J
7N9H
8FZK
8GCN
Enriched GO Terms of Interacting Partners
?
Cytoskeleton
Intermediate Filament Organization
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Structural Constituent Of Skin Epidermis
Keratin Filament
Protein Binding
Cytoskeleton Organization
Intermediate Filament
Microtubule-based Process
Organelle Organization
Structural Molecule Activity
Microtubule Cytoskeleton Organization
Centrosome
Supramolecular Fiber Organization
Cytoplasm
Structural Constituent Of Cytoskeleton
Spindle Pole
Establishment Of Spindle Orientation
Microtubule Organizing Center Organization
Establishment Of Mitotic Spindle Orientation
Epithelial Cell Differentiation
Establishment Of Spindle Localization
Establishment Of Mitotic Spindle Localization
Spindle Localization
Motile Cilium
Organelle Localization
Chromosome, Centromeric Region
Centriole
Kinetochore
Microtubule-based Movement
Positive Regulation Of Ubiquitin-dependent Endocytosis
Morphogenesis Of An Epithelium
Microtubule
Axonemal A Tubule Inner Sheath
Negative Regulation Of Cell Cycle Phase Transition
Establishment Of Organelle Localization
Membrane Fission
Protein Deneddylation
CENP-A Containing Chromatin Assembly
Ciliary Basal Body
Microtubule Cytoskeleton Organization Involved In Mitosis
Spindle Organization
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Cis-Golgi Network
Centrosome Cycle
Regulation Of Post-translational Protein Modification
Cilium Movement
Centriole Assembly
Cilium
Nucleus
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Metabolic Process
Regulation Of Primary Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Metabolic Process
Identical Protein Binding
Regulation Of RNA Metabolic Process
Nucleoplasm
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of RNA Metabolic Process
Chromatin Organization
Regulation Of Programmed Cell Death
Negative Regulation Of Transcription By RNA Polymerase II
Ubiquitin Protein Ligase Binding
Intracellular Signal Transduction
DNA Damage Response
Cytoplasm
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Apoptotic Process
Regulation Of Signal Transduction
Negative Regulation Of Biosynthetic Process
Cytosol
Positive Regulation Of Response To Endoplasmic Reticulum Stress
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Transcription By RNA Polymerase II
Protein-containing Complex
Protein Binding
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Nuclear Inclusion Body
Positive Regulation Of Proteolysis
Regulation Of Protein Catabolic Process
Negative Regulation Of Catabolic Process
Regulation Of Transcription By RNA Polymerase II
Protein Import Into Nucleus
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Tagcloud (Intersection)
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