USHBP1 and NGFRAP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		USHBP1	NGFRAP1
Gene Name		Usher syndrome 1C binding protein 1	nerve growth factor receptor (TNFRSF16) associated protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding PDZ Domain Binding	Death Receptor Binding Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Metal Ion Binding
	Biological Process		Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Multicellular Organismal Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Apoptotic Signaling Pathway
Pathways			Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE p75 NTR receptor-mediated signalling NADE modulates death signalling
Drugs
Diseases
GWAS
Protein-Protein Interactions		124 interactors: ABLIM1 AKAP9 ANKRD36BP1 ARFIP2 ARNT2 ATP5O BCL10 BET1 C10orf10 C1orf109 C1orf216 C6orf165 CCDC116 CCDC120 CCDC121 CCDC146 CCDC148 CCDC22 CCDC24 CCDC33 CCDC87 CCHCR1 CCNK CENPP CEP63 CEP68 CHCHD3 CNNM3 COPS4 COPS8 CTNNBIP1 CTTNBP2NL DTNB DYDC1 EIF4E2 ERCC1 EXOC7 EXOC8 FAM107A FAM110A FAM124B FANCG FATE1 FBF1 FTL GATAD2B GCC1 GFI1B GIT2 GMCL1P1 GNG4 GOLGA8EP GOLGA8F GPSM1 GPSM3 GTF2H1 HAUS1 HGS IFT20 IL16 IMP3 ING3 INPP1 INTS4 KANSL1 KIAA0753 KLC3 KLC4 KLHL38 KLHL42 KPNA2 KRT15 KRT19 KRT20 KRT31 KRT38 KRT40 KRT79 LENG1 LINC00526 MAGEB4 MCM7 MCRS1 MED28 MED4 MOS MRPS23 NCAPH2 NDC80 NDE1 NGFRAP1 NOC4L PARVG PMF1 PPP1R7 PPP2R5D PRC1 PRKAA2 RASAL2 RECK RIBC2 RNF20 SEC14L4 SERTAD3 SH2D4A SMARCD1 SMARCE1 STX11 SYNJ2BP THADA THOC1 TRIM54 TSG101 TUBGCP4 TXLNA TXLNB UBE2W UBXN11 USH1C VPS28 ZFYVE26 ZNF483 ZNF765 ZNRF2P1	28 interactors: AIMP2 CACYBP CCDC116 CCDC85B CTNNBL1 DIABLO EMILIN1 FSD2 GOLGA8EP GOLGA8F MIF MNAT1 NECAB2 NGFR NTRK3 PTPN13 SIVA1 SMPD1 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 TSC1 USHBP1 VTA1 YWHAE
Entrez ID		83878	27018
HPRD ID		18276	02291
Ensembl ID		ENSG00000130307	ENSG00000166681
Uniprot IDs		G8JLM4 Q8N6Y0	Q00994
PDB IDs			1SA6
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Process Cell Cycle Cell Division Mitotic Cell Cycle Chromosome Organization Mitotic Cell Cycle Process Establishment Of Localization In Cell Cytoskeleton Organization Cellular Localization Microtubule-based Process Microtubule Cytoskeleton Organization Chromatin Organization Chromatin Modification G2/M Transition Of Mitotic Cell Cycle Spindle Organization Regulation Of Metabolic Process Intracellular Transport Of Virus Intracellular Transport Mitotic Nuclear Division Centrosome Organization Cellular Process Cullin Deneddylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Establishment Of Spindle Orientation Microtubule Organizing Center Organization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Deneddylation Viral Protein Processing Establishment Of Cell Polarity Histone H4 Acetylation Spindle Localization Cellular Response To DNA Damage Stimulus Histone H4-K5 Acetylation Histone H4-K8 Acetylation Membrane Organization Histone H4-K16 Acetylation Nucleosome Disassembly ATP-dependent Chromatin Remodeling Nucleotide-excision Repair, DNA Damage Removal Microtubule Nucleation Organelle Fusion Protein Targeting To Vacuole Virion Assembly	Regulation Of Cell Death Regulation Of Apoptotic Process Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Protein Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Signal Transduction Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling Positive Regulation Of Signal Transduction Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Metabolic Process Positive Regulation Of NIK/NF-kappaB Signaling Regulation Of Catalytic Activity Regulation Of Protein Phosphorylation Regulation Of Phosphorus Metabolic Process NIK/NF-kappaB Signaling Positive Regulation Of Cellular Protein Metabolic Process Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Regulation Of Cellular Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Intracellular Signal Transduction Regulation Of Phosphorylation Apoptotic Signaling Pathway Positive Regulation Of Cytokine Production Involved In Immune Response Cellular Response To Stimulus Regulation Of MAPK Cascade Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Cell Death TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Signal Transduction Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Signaling Pathway Response To Organic Substance MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity
Tagcloud ?			abcf2 adprtl1 amy2b arhgap4 atp6ap1 axin1 casp4 cox1 cox7b ctsl etv4 lgals3bp mgc35136 mgc5528 mt2a mt3 p53scv ppia prdx2 psap scgb2a2 smoc2 sptan1 sra1 tax1bp1 tpd52l1 tra1 trf4 tuba4
Tagcloud (Difference) ?			abcf2 adprtl1 amy2b arhgap4 atp6ap1 axin1 casp4 cox1 cox7b ctsl etv4 lgals3bp mgc35136 mgc5528 mt2a mt3 p53scv ppia prdx2 psap scgb2a2 smoc2 sptan1 sra1 tax1bp1 tpd52l1 tra1 trf4 tuba4
Tagcloud (Intersection) ?