USHBP1 and CEP63

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		USHBP1	CEP63
Gene Name		Usher syndrome 1C binding protein 1	centrosomal protein 63kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Spindle Pole Centrosome Centriole Cytosol
	Molecular Function	Protein Binding PDZ Domain Binding	Protein Binding
	Biological Process		DNA Damage Checkpoint G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Centriole Replication Signal Transduction In Response To DNA Damage Spindle Assembly Cell Division
Pathways			Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Height ( 18391952)
Protein-Protein Interactions		124 interactors: ABLIM1 AKAP9 ANKRD36BP1 ARFIP2 ARNT2 ATP5O BCL10 BET1 C10orf10 C1orf109 C1orf216 C6orf165 CCDC116 CCDC120 CCDC121 CCDC146 CCDC148 CCDC22 CCDC24 CCDC33 CCDC87 CCHCR1 CCNK CENPP CEP63 CEP68 CHCHD3 CNNM3 COPS4 COPS8 CTNNBIP1 CTTNBP2NL DTNB DYDC1 EIF4E2 ERCC1 EXOC7 EXOC8 FAM107A FAM110A FAM124B FANCG FATE1 FBF1 FTL GATAD2B GCC1 GFI1B GIT2 GMCL1P1 GNG4 GOLGA8EP GOLGA8F GPSM1 GPSM3 GTF2H1 HAUS1 HGS IFT20 IL16 IMP3 ING3 INPP1 INTS4 KANSL1 KIAA0753 KLC3 KLC4 KLHL38 KLHL42 KPNA2 KRT15 KRT19 KRT20 KRT31 KRT38 KRT40 KRT79 LENG1 LINC00526 MAGEB4 MCM7 MCRS1 MED28 MED4 MOS MRPS23 NCAPH2 NDC80 NDE1 NGFRAP1 NOC4L PARVG PMF1 PPP1R7 PPP2R5D PRC1 PRKAA2 RASAL2 RECK RIBC2 RNF20 SEC14L4 SERTAD3 SH2D4A SMARCD1 SMARCE1 STX11 SYNJ2BP THADA THOC1 TRIM54 TSG101 TUBGCP4 TXLNA TXLNB UBE2W UBXN11 USH1C VPS28 ZFYVE26 ZNF483 ZNF765 ZNRF2P1	44 interactors: ALOX5 ARFIP2 ARNT2 CAMKK2 CCDC14 CCNI CEP57 CEP57L1 DDX26B DISC1 DST DTNB DZIP3 EXOC4 EZH2 FAM161A FBF1 GSE1 HAUS1 KXD1 MACF1 MBIP NCOR2 NDEL1 NXT2 PCNXL4 POLR3C PPP1R13B PPP4R1 SMARCE1 SMC3 SNRNP70 SPTAN1 SPTBN1 SSX3 SYNE1 SYT17 TANK TBC1D15 TSHZ3 TXLNA TXLNB USHBP1 ZCCHC10
Entrez ID		83878	80254
HPRD ID		18276	07826
Ensembl ID		ENSG00000130307	ENSG00000182923
Uniprot IDs		G8JLM4 Q8N6Y0	Q96MT8
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Process Cell Cycle Cell Division Mitotic Cell Cycle Chromosome Organization Mitotic Cell Cycle Process Establishment Of Localization In Cell Cytoskeleton Organization Cellular Localization Microtubule-based Process Microtubule Cytoskeleton Organization Chromatin Organization Chromatin Modification G2/M Transition Of Mitotic Cell Cycle Spindle Organization Regulation Of Metabolic Process Intracellular Transport Of Virus Intracellular Transport Mitotic Nuclear Division Centrosome Organization Cellular Process Cullin Deneddylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Establishment Of Spindle Orientation Microtubule Organizing Center Organization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Deneddylation Viral Protein Processing Establishment Of Cell Polarity Histone H4 Acetylation Spindle Localization Cellular Response To DNA Damage Stimulus Histone H4-K5 Acetylation Histone H4-K8 Acetylation Membrane Organization Histone H4-K16 Acetylation Nucleosome Disassembly ATP-dependent Chromatin Remodeling Nucleotide-excision Repair, DNA Damage Removal Microtubule Nucleation Organelle Fusion Protein Targeting To Vacuole Virion Assembly	Microtubule Cytoskeleton Organization Organelle Organization Cytoskeleton Organization Microtubule-based Process Cell Cycle Process Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Cell Cycle Cellular Localization Golgi To Plasma Membrane Protein Transport Cell Cycle Maintenance Of Protein Location In Cell Maintenance Of Protein Location Brain Development Maintenance Of Location In Cell Protein Localization To Organelle Head Development Anatomical Structure Development Golgi To Plasma Membrane Transport Regulation Of Cellular Component Size Positive Regulation Of Axon Extension Intermediate Filament Cytoskeleton Organization Microtubule Anchoring Protein Localization Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Leukotriene Production Involved In Inflammatory Response Kidney Smooth Muscle Cell Differentiation Ureteric Peristalsis Nervous System Development Intermediate Filament-based Process Positive Regulation Of Cell Morphogenesis Involved In Differentiation Protein Localization To Nucleus Regulation Of Cell Cycle Cell Proliferation In Forebrain Actin Filament Capping Central Nervous System Development Mitotic Cell Cycle Process Cellular Protein Localization Cerebral Cortex Radially Oriented Cell Migration Endomembrane System Organization Negative Regulation Of Actin Filament Depolymerization Developmental Process
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