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USHBP1 and GTF2H1
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
USHBP1
GTF2H1
Gene Name
Usher syndrome 1C binding protein 1
general transcription factor IIH, polypeptide 1, 62kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Core TFIIH Complex
Nucleoplasm
Holo TFIIH Complex
Molecular Function
Protein Binding
PDZ Domain Binding
Protein Kinase Activity
Protein Binding
DNA-dependent ATPase Activity
RNA Polymerase II Carboxy-terminal Domain Kinase Activity
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Nucleotide-excision Repair, DNA Damage Removal
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Protein Phosphorylation
Gene Expression
Viral Process
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Viral Transcription
Pathways
RNA Polymerase II Promoter Escape
Formation of HIV-1 elongation complex containing HIV-1 Tat
Nucleotide Excision Repair
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Clearance
HIV Infection
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Formation of transcription-coupled NER (TC-NER) repair complex
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
Dual incision reaction in TC-NER
NoRC negatively regulates rRNA expression
HIV Transcription Initiation
HIV Life Cycle
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
Dual incision reaction in GG-NER
mRNA Capping
RNA Polymerase I Transcription
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
Global Genomic NER (GG-NER)
RNA Polymerase II Transcription Initiation And Promoter Clearance
Transcription-coupled NER (TC-NER)
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
Formation of incision complex in GG-NER
RNA Polymerase II Transcription Initiation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Amyloid A Levels (
21124955
)
Pancreatic cancer (
23180869
)
Protein-Protein Interactions
124 interactors:
ABLIM1
AKAP9
ANKRD36BP1
ARFIP2
ARNT2
ATP5O
BCL10
BET1
C10orf10
C1orf109
C1orf216
C6orf165
CCDC116
CCDC120
CCDC121
CCDC146
CCDC148
CCDC22
CCDC24
CCDC33
CCDC87
CCHCR1
CCNK
CENPP
CEP63
CEP68
CHCHD3
CNNM3
COPS4
COPS8
CTNNBIP1
CTTNBP2NL
DTNB
DYDC1
EIF4E2
ERCC1
EXOC7
EXOC8
FAM107A
FAM110A
FAM124B
FANCG
FATE1
FBF1
FTL
GATAD2B
GCC1
GFI1B
GIT2
GMCL1P1
GNG4
GOLGA8EP
GOLGA8F
GPSM1
GPSM3
GTF2H1
HAUS1
HGS
IFT20
IL16
IMP3
ING3
INPP1
INTS4
KANSL1
KIAA0753
KLC3
KLC4
KLHL38
KLHL42
KPNA2
KRT15
KRT19
KRT20
KRT31
KRT38
KRT40
KRT79
LENG1
LINC00526
MAGEB4
MCM7
MCRS1
MED28
MED4
MOS
MRPS23
NCAPH2
NDC80
NDE1
NGFRAP1
NOC4L
PARVG
PMF1
PPP1R7
PPP2R5D
PRC1
PRKAA2
RASAL2
RECK
RIBC2
RNF20
SEC14L4
SERTAD3
SH2D4A
SMARCD1
SMARCE1
STX11
SYNJ2BP
THADA
THOC1
TRIM54
TSG101
TUBGCP4
TXLNA
TXLNB
UBE2W
UBXN11
USH1C
VPS28
ZFYVE26
ZNF483
ZNF765
ZNRF2P1
42 interactors:
ACTN1
AR
ATF7IP
BRPF1
CCNH
CCSER2
CDK7
CTD
E2F1
ERCC2
ERCC3
ERCC4
ERCC5
ESR1
FUBP1
GTF2E1
GTF2E2
GTF2H2
GTF2H3
HNF4A
HNRNPU
HOXC11
JDP2
KIF13A
KPNA3
MCM2
MMS19
PIK3R1
PLCG1
POU2AF1
PSMC2
RAD23A
REEP5
RXRB
TNIP1
TP53
TRIOBP
TXNRD2
USHBP1
XPA
XPC
ZSCAN1
Entrez ID
83878
2965
HPRD ID
18276
01807
Ensembl ID
ENSG00000130307
ENSG00000110768
Uniprot IDs
G8JLM4
Q8N6Y0
P32780
PDB IDs
1PFJ
2DII
2RNR
Enriched GO Terms of Interacting Partners
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Organelle Organization
Cell Cycle Process
Cell Cycle
Cell Division
Mitotic Cell Cycle
Chromosome Organization
Mitotic Cell Cycle Process
Establishment Of Localization In Cell
Cytoskeleton Organization
Cellular Localization
Microtubule-based Process
Microtubule Cytoskeleton Organization
Chromatin Organization
Chromatin Modification
G2/M Transition Of Mitotic Cell Cycle
Spindle Organization
Regulation Of Metabolic Process
Intracellular Transport Of Virus
Intracellular Transport
Mitotic Nuclear Division
Centrosome Organization
Cellular Process
Cullin Deneddylation
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Establishment Of Spindle Orientation
Microtubule Organizing Center Organization
Positive Regulation Of Exosomal Secretion
Regulation Of Exosomal Secretion
Protein Deneddylation
Viral Protein Processing
Establishment Of Cell Polarity
Histone H4 Acetylation
Spindle Localization
Cellular Response To DNA Damage Stimulus
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Membrane Organization
Histone H4-K16 Acetylation
Nucleosome Disassembly
ATP-dependent Chromatin Remodeling
Nucleotide-excision Repair, DNA Damage Removal
Microtubule Nucleation
Organelle Fusion
Protein Targeting To Vacuole
Virion Assembly
Nucleotide-excision Repair, DNA Damage Removal
Nucleotide-excision Repair
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Transcription-coupled Nucleotide-excision Repair
Viral Process
Cellular Response To DNA Damage Stimulus
Transcription From RNA Polymerase II Promoter
DNA Catabolic Process
Transcription Elongation From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription, DNA-templated
Positive Regulation Of Gene Expression
Response To UV
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
DNA-templated Transcription, Elongation
Positive Regulation Of Cellular Biosynthetic Process
RNA Biosynthetic Process
Termination Of RNA Polymerase I Transcription
Gene Expression
Transcription Elongation From RNA Polymerase I Promoter
Nitrogen Compound Metabolic Process
DNA Repair
Transcription Initiation From RNA Polymerase I Promoter
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription, DNA-templated
7-methylguanosine MRNA Capping
Transcription From RNA Polymerase I Promoter
7-methylguanosine RNA Capping
Positive Regulation Of Viral Process
DNA Metabolic Process
RNA Metabolic Process
Cellular Response To Stress
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Viral Transcription
Regulation Of Viral Process
Nucleotide-excision Repair, DNA Incision
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Metabolic Process
Regulation Of Viral Transcription
Response To Stress
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