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NR2C2 and ITSN2
Number of citations of the paper that reports this interaction (PMID
22558309
)
5
Data Source:
BioGRID
(two hybrid)
NR2C2
ITSN2
Gene Name
nuclear receptor subfamily 2, group C, member 2
intersectin 2
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
Sequence-specific DNA Binding Transcription Factor Activity
Steroid Hormone Receptor Activity
Transcription Coactivator Activity
Receptor Activity
Protein Binding
Zinc Ion Binding
Sequence-specific DNA Binding
Protein Heterodimerization Activity
SH3/SH2 Adaptor Activity
Rho Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Protein Binding
Biological Process
Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Spermatogenesis
Nervous System Development
Gene Expression
Cerebellum Development
Cell Differentiation
Positive Regulation Of Embryonic Development
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Behavior
Meiotic Cell Cycle
Endocytosis
Positive Regulation Of Signal Transduction
Positive Regulation Of Rho GTPase Activity
Pathways
Generic Transcription Pathway
Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS
Alcohol and nictotine co-dependence (
22488850
)
Working memory (
21107309
)
Protein-Protein Interactions
21 interactors:
AR
CD2AP
CDC37
CHUK
ESR1
FKBP5
HDAC4
HNF4A
HSP90AA1
HSP90AB1
IKBKB
ITSN2
JAZF1
KDM1A
NR2C1
NR2C2AP
PEBP1
RXRB
TAB1
TAB2
TRAF2
75 interactors:
AGT
AHDC1
AMPH
ANKRD17
BCCIP
CBL
CCDC88C
CHIC2
CPSF6
DLGAP1
DNM2
DST
EPS15
EPS15L1
ERC1
FASLG
FCHSD1
FCHSD2
FNBP4
GAREML
GOLGA2
GOLGA8A
GOLGB1
GPNMB
HNRNPK
HOOK2
ITPKA
ITSN1
KCTD10
KDM1A
KHDRBS1
KIAA1549
KXD1
LARP6
LSM8
LTBP4
LUC7L3
MAP4K3
MBNL1
MEGF10
NBR1
NR2C2
PDCD6IP
PDE4DIP
PIK3AP1
PIK3C2B
PSEN1
PTN
RABEP1
RAD9A
RBMX
REPS1
RNF20
ROCK1
RUFY1
SEMA6A
SH3GL1
SH3KBP1
SNAP29
SOS1
SOS2
STX4
SYN1
SYNJ2
TACC1
TBL3
TMF1
TRIO
WAS
WASF2
WASL
WIPF1
WIPF2
YLPM1
YTHDF1
Entrez ID
7182
50618
HPRD ID
03253
09193
Ensembl ID
ENSG00000198399
Uniprot IDs
F2YGU2
P49116
Q6PHZ7
A6H8W8
Q9NZM3
PDB IDs
3P0U
1J3T
1UDL
1UE9
1UFF
1UHF
3GF9
3JZY
Enriched GO Terms of Interacting Partners
?
Intracellular Receptor Signaling Pathway
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Innate Immune Response
I-kappaB Kinase/NF-kappaB Signaling
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Transcription Initiation From RNA Polymerase II Promoter
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
DNA-templated Transcription, Initiation
Toll-like Receptor Signaling Pathway
Regulation Of Signal Transduction
Positive Regulation Of Metabolic Process
Hormone-mediated Signaling Pathway
Immune Response-regulating Signaling Pathway
Fc Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Toll-like Receptor 5 Signaling Pathway
Activation Of Innate Immune Response
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Regulation Of Signaling
Toll-like Receptor 2 Signaling Pathway
Response To Organic Substance
Toll-like Receptor 9 Signaling Pathway
Positive Regulation Of Cellular Biosynthetic Process
Cellular Response To Steroid Hormone Stimulus
Regulation Of Immune Response
Regulation Of Metabolic Process
MyD88-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Innate Immune Response
Positive Regulation Of Immune System Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Immune System Process
Cellular Response To Organic Cyclic Compound
Positive Regulation Of Immune Response
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Organic Substance
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Innate Immune Response
Immune Response-activating Cell Surface Receptor Signaling Pathway
Vesicle-mediated Transport
Endocytosis
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Cell Communication
Signaling
Cellular Response To Stimulus
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Cellular Component Assembly
Signal Transduction
Synaptic Vesicle Transport
Enzyme Linked Receptor Protein Signaling Pathway
Actin Filament-based Movement
Cell-cell Signaling
Response To Stimulus
Establishment Of Vesicle Localization
Cell Surface Receptor Signaling Pathway
Vesicle Localization
Organelle Localization
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Cellular Component Organization
Regulation Of Cellular Process
Negative Regulation Of Membrane Tubulation
Regulation Of Signaling
Protein Complex Assembly
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger
Vesicle Organization
Establishment Of Organelle Localization
Positive Regulation Of Apoptotic Process
Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Immune Response-regulating Signaling Pathway
Positive Regulation Of ERBB Signaling Pathway
Movement Of Cell Or Subcellular Component
Positive Regulation Of Cell Death
Transport
Apoptotic Process
Cellular Localization
Regulation Of Cell Death
Positive Regulation Of Intracellular Signal Transduction
Organelle Organization
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Differentiation
Regulation Of Vesicle-mediated Transport
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Establishment Of Localization In Cell
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Tagcloud
?
abl1
adaptor
clathrin
colocalize
crk
domains
enabled
endocytosis
fgr
fyn
hela
interactors
interface
intersectin
isoform
isoforms
itsn1
itsns
mentioned
paralogous
pathologies
phospholipase
scaffolding
sh2
sh3
tyrosines
unable
vertebrates
Tagcloud (Difference)
?
abl1
adaptor
clathrin
colocalize
crk
domains
enabled
endocytosis
fgr
fyn
hela
interactors
interface
intersectin
isoform
isoforms
itsn1
itsns
mentioned
paralogous
pathologies
phospholipase
scaffolding
sh2
sh3
tyrosines
unable
vertebrates
Tagcloud (Intersection)
?