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NR2C2 and FKBP5
Number of citations of the paper that reports this interaction (PMID
14743216
)
197
Data Source:
HPRD
(in vitro)
NR2C2
FKBP5
Gene Name
nuclear receptor subfamily 2, group C, member 2
FK506 binding protein 5
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Nucleoplasm
Endoplasmic Reticulum Membrane
Membrane
Extracellular Vesicular Exosome
Molecular Function
Sequence-specific DNA Binding Transcription Factor Activity
Steroid Hormone Receptor Activity
Transcription Coactivator Activity
Receptor Activity
Protein Binding
Zinc Ion Binding
Sequence-specific DNA Binding
Protein Heterodimerization Activity
Peptidyl-prolyl Cis-trans Isomerase Activity
Protein Binding
FK506 Binding
Heat Shock Protein Binding
Biological Process
Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Spermatogenesis
Nervous System Development
Gene Expression
Cerebellum Development
Cell Differentiation
Positive Regulation Of Embryonic Development
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Behavior
Meiotic Cell Cycle
Protein Peptidyl-prolyl Isomerization
Protein Folding
Chaperone-mediated Protein Folding
Pathways
Generic Transcription Pathway
Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS
Alcohol and nictotine co-dependence (
22488850
)
Protein-Protein Interactions
21 interactors:
AR
CD2AP
CDC37
CHUK
ESR1
FKBP5
HDAC4
HNF4A
HSP90AA1
HSP90AB1
IKBKB
ITSN2
JAZF1
KDM1A
NR2C1
NR2C2AP
PEBP1
RXRB
TAB1
TAB2
TRAF2
10 interactors:
APP
CHUK
ESR1
FES
HSF1
HSP90AA1
IKBKE
NR2C2
PGR
STIP1
Entrez ID
7182
2289
HPRD ID
03253
04019
Ensembl ID
ENSG00000096060
Uniprot IDs
F2YGU2
P49116
Q6PHZ7
Q13451
Q2TA84
PDB IDs
3P0U
1KT0
3O5D
3O5E
3O5F
3O5G
3O5I
3O5J
3O5K
3O5L
3O5M
3O5O
3O5P
3O5Q
3O5R
4DRH
4DRI
4DRK
4DRM
4DRN
4DRO
4DRP
4DRQ
4JFI
4JFJ
4JFK
4JFL
4JFM
Enriched GO Terms of Interacting Partners
?
Intracellular Receptor Signaling Pathway
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Innate Immune Response
I-kappaB Kinase/NF-kappaB Signaling
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Transcription Initiation From RNA Polymerase II Promoter
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
DNA-templated Transcription, Initiation
Toll-like Receptor Signaling Pathway
Regulation Of Signal Transduction
Positive Regulation Of Metabolic Process
Hormone-mediated Signaling Pathway
Immune Response-regulating Signaling Pathway
Fc Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Toll-like Receptor 5 Signaling Pathway
Activation Of Innate Immune Response
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Regulation Of Signaling
Toll-like Receptor 2 Signaling Pathway
Response To Organic Substance
Toll-like Receptor 9 Signaling Pathway
Positive Regulation Of Cellular Biosynthetic Process
Cellular Response To Steroid Hormone Stimulus
Regulation Of Immune Response
Regulation Of Metabolic Process
MyD88-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Innate Immune Response
Positive Regulation Of Immune System Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Immune System Process
Cellular Response To Organic Cyclic Compound
Positive Regulation Of Immune Response
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Organic Substance
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Innate Immune Response
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cellular Biosynthetic Process
Intracellular Receptor Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Mammary Gland Branching Involved In Pregnancy
Positive Regulation Of Transcription, DNA-templated
Defense Response
Steroid Hormone Mediated Signaling Pathway
Mammary Gland Epithelium Development
Innate Immune Response
Positive Regulation Of Macromolecule Biosynthetic Process
Response To Lipid
Positive Regulation Of Gene Expression
I-kappaB Phosphorylation
Positive Regulation Of Cellular Metabolic Process
Hormone-mediated Signaling Pathway
Response To Stimulus
System Development
Reproduction
Mammary Gland Epithelial Cell Proliferation
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Mammary Gland Development
Cellular Response To Steroid Hormone Stimulus
Regulation Of Cellular Response To Heat
Cellular Response To Stimulus
Multicellular Organismal Development
Immune Response
DNA-templated Transcription, Initiation
Anatomical Structure Development
Cell Differentiation
Positive Regulation Of Metabolic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Reproductive Process
Protein Phosphorylation
Response To Stress
Female Pregnancy
Regulation Of Nitric-oxide Synthase Activity
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Reactive Oxygen Species Biosynthetic Process
Mammary Gland Lobule Development
Mammary Gland Alveolus Development
Anatomical Structure Morphogenesis
Signal Transduction
Branching Involved In Mammary Gland Duct Morphogenesis
Response To Organic Substance
Sexual Reproduction
Developmental Process
Multicellular Organismal Reproductive Process
I-kappaB Kinase/NF-kappaB Signaling
Tagcloud
?
12q13
4x10
bd
bdi
bdnf
beck
bipolar
dbh
depression
depressive
dhh
etiology
gwas
gwass
gxe
interplay
inventory
marginally
mdd
pcorrected
personality
puncorrected
rs4523957
rs7296288
scz
slc6a4
sles
stressful
unsuccessful
Tagcloud (Difference)
?
12q13
4x10
bd
bdi
bdnf
beck
bipolar
dbh
depression
depressive
dhh
etiology
gwas
gwass
gxe
interplay
inventory
marginally
mdd
pcorrected
personality
puncorrected
rs4523957
rs7296288
scz
slc6a4
sles
stressful
unsuccessful
Tagcloud (Intersection)
?